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Inter-alpha Globulin Inhibitor H2 Polypeptide Proteins (ITIH2)

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. Additionally we are shipping ITIH2 Antibodies (25) and ITIH2 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITIH2 16425 Q61703
ITIH2 3698 P19823
ITIH2 512164  
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Top ITIH2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,020.33
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ITIH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Cow (Bovine)

More Proteins for Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2) Interaction Partners

Human Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2) interaction partners

  1. Data suggest that Mg2 (show MUC7 Proteins)+ or Mn2+ (but not Ca2 (show CA2 Proteins)+) induce a conformational change in inter-alpha-inhibitor (ITIH1 (show ITIH1 Proteins) and ITIH2) and a bikunin (show AMBP Proteins)/chondroitin sulfate-dependent increase in thermodynamic stability; bikunin (show AMBP Proteins) binds adjacent to the two heavy chains.

  2. Human inter-alpha-inhibitor is a substrate for factor XIIIa (show F13A1 Proteins) and tissue transglutaminase (show TGM2 Proteins).

  3. TSG-6 (show TNFAIP6 Proteins) acts as cofactor and catalyst in the production of IalphaI heavy chain x hyaluronan complexes

  4. Leukocytes infiltrated to the synovium were strongly positive for hyaluronic acid, SHAP, and CD44 on their surfaces, suggesting a role for the adhesion-enhancing effect of SHAP in inflammation.

  5. Increased levels of SHAP-HA complex in sera are possible predictive markers for cervical ripening in premature labor.

  6. serum-derived hyaluronan-associated protein (show ITIH1 Proteins)-hyaluronan complex has a role in progression of ovarian cancer

ITIH2 Protein Profile

Protein Summary

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987

Gene names and symbols associated with ITIH2

  • inter-alpha trypsin inhibitor, heavy chain 2 (Itih2)
  • inter-alpha-trypsin inhibitor heavy chain 2 (ITIH2)
  • inter-alpha-trypsin inhibitor heavy chain 2 (Itih2)
  • AI747202 protein
  • H2P protein
  • Intin2 protein
  • ITI-HC2 protein
  • Itih-2 protein
  • SHAP protein

Protein level used designations for ITIH2

ITI heavy chain H2 , ITI-HC2 , inter-alpha-inhibitor heavy chain 2 , inter-alpha-trypsin inhibitor heavy chain H2 , inter-alpha (globulin) inhibitor H2 , inter-alpha (globulin) inhibitor, H2 polypeptide , inter-alpha-trypsin inhibitor complex component II , serum-derived hyaluronan-associated protein , inter-alpha globulin inhibitor H2 polypeptide , inter-alpha-inhibitor heavy-chain H2 , Inter-alpha-inhibitor heavy chain 2

GENE ID SPECIES
16425 Mus musculus
3698 Homo sapiens
512164 Bos taurus
396937 Sus scrofa
101837243 Mesocricetus auratus
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