Interferon, alpha-Inducible Protein 6 Proteins (IFI6)

IFI6 was first identified as one of the many genes induced by interferon. Additionally we are shipping IFI6 Antibodies (47) and IFI6 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IFI6 2537 P09912
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Top IFI6 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
Yeast Human His tag   50 μg Log in to see 8 to 11 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

IFI6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Interferon, alpha-Inducible Protein 6 (IFI6) Interaction Partners

Human Interferon, alpha-Inducible Protein 6 (IFI6) interaction partners

  1. In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (show GBP1 Proteins), TLR3 (show TLR3 Proteins), OAS1 (show OAS1 Proteins), EIF2AK2 (show EIF2AK2 Proteins), HLA-E (show HLAE Proteins), IFI6, and STAT1 (show STAT1 Proteins), showed higher expression in the islet core compared with the peri (show PLIN1 Proteins)-islet area containing the surrounding immune cells

  2. In conclusion, over-expression of IFI6 promotes hepatitis C virus RNA replication and rescues the interferon alpha (show IFNA Proteins)-mediated anti-hepatitis C virus activity.

  3. IFI6 inhibits HCV entry by impairing EGFR (show EGFR Proteins) mediated CD81 (show CD81 Proteins)/CLDN1 (show CLDN1 Proteins) interactions. This may be relevant to other virus entry processes employing EGFR (show EGFR Proteins).

  4. Here we elucidate G1P3, a survival protein induced by interferons (IFNs), as a target of estrogen signaling and a contributor to poor outcomes in estrogen receptor (show ESR1 Proteins)-positive (ER(+)) breast cancer.

  5. PRINS regulates G1P3, a gene with anti-apoptotic effects in keratinocytes. siRNA-mediated inhibition of PRINS gene resulted in altered cell morphology and gene expression alterations.

  6. G1P3 protein may have function as a cell survival protein by inhibiting mitochondrial-mediated apoptosis

  7. Respiratory syncytial virus upregulated the mRNA expression of chemokines CC and CXC and interfered with type alpha/beta interferon (show IFNA Proteins)-inducible gene expression by upregulation of MG11 (show SAMHD1 Proteins) and downregulation of G1P3.

  8. IFN-alpha2b (show ADRA2B Proteins) induced the expression of G1P3 and antagonized the TRAIL induced apoptosis in myeloma suggesting that either the deregulated or the induced expression of G1P3 could lead to apoptosis resistance in tumor cells.

IFI6 Protein Profile

Protein Summary

This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.

Gene names and symbols associated with IFI6

  • interferon, alpha-inducible protein 6 (IFI6)
  • interferon alpha inducible protein 6 (IFI6)
  • 6-16 protein
  • FAM14C protein
  • G1P3 protein
  • Ifi-6-16 protein
  • IFI616 protein

Protein level used designations for IFI6

interferon alpha-inducible protein 6 , interferon, alpha-inducible protein clone IFI-6-16 , interferon-induced protein 6-16 , ifi-6-16

100190421 Taeniopygia guttata
2537 Homo sapiens
512913 Bos taurus
450178 Pan troglodytes
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