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IFI6 was first identified as one of the many genes induced by interferon. Additionally we are shipping IFI6 Antibodies (47) and IFI6 Proteins (3) and many more products for this protein.
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In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (show GBP1 ELISA Kits), TLR3 (show TLR3 ELISA Kits), OAS1 (show OAS1 ELISA Kits), EIF2AK2 (show EIF2AK2 ELISA Kits), HLA-E (show HLAE ELISA Kits), IFI6, and STAT1 (show STAT1 ELISA Kits), showed higher expression in the islet core compared with the peri (show PLIN1 ELISA Kits)-islet area containing the surrounding immune cells
In conclusion, over-expression of IFI6 promotes hepatitis C virus RNA replication and rescues the interferon alpha (show IFNA ELISA Kits)-mediated anti-hepatitis C virus activity.
IFI6 inhibits HCV entry by impairing EGFR (show EGFR ELISA Kits) mediated CD81 (show CD81 ELISA Kits)/CLDN1 (show CLDN1 ELISA Kits) interactions. This may be relevant to other virus entry processes employing EGFR (show EGFR ELISA Kits).
Here we elucidate G1P3, a survival protein induced by interferons (IFNs), as a target of estrogen signaling and a contributor to poor outcomes in estrogen receptor (show ESR1 ELISA Kits)-positive (ER(+)) breast cancer.
PRINS regulates G1P3, a gene with anti-apoptotic effects in keratinocytes. siRNA-mediated inhibition of PRINS gene resulted in altered cell morphology and gene expression alterations.
G1P3 protein may have function as a cell survival protein by inhibiting mitochondrial-mediated apoptosis
Respiratory syncytial virus upregulated the mRNA expression of chemokines CC and CXC and interfered with type alpha/beta interferon (show IFNA ELISA Kits)-inducible gene expression by upregulation of MG11 (show SAMHD1 ELISA Kits) and downregulation of G1P3.
IFN-alpha2b (show ADRA2B ELISA Kits) induced the expression of G1P3 and antagonized the TRAIL induced apoptosis in myeloma suggesting that either the deregulated or the induced expression of G1P3 could lead to apoptosis resistance in tumor cells.
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.
interferon alpha-inducible protein 6
, interferon, alpha-inducible protein clone IFI-6-16
, interferon-induced protein 6-16