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Interferon Induced Transmembrane Protein 2 Proteins (IFITM2)

IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Additionally we are shipping IFITM2 Antibodies (34) and IFITM2 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IFITM2 10581 Q01629
IFITM2 80876 Q99J93
Rat IFITM2 IFITM2 114709  
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Top IFITM2 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His-GST 10% SDS-PAGE stained with Coomassie Blue (CB) and peptide fingerprinting by MALDI-TOF mass spectrometry 50 μg Log in to see 5 to 7 Days
$317.63
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

IFITM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Interferon Induced Transmembrane Protein 2 (IFITM2) Interaction Partners

Human Interferon Induced Transmembrane Protein 2 (IFITM2) interaction partners

  1. IFITM2 and IFITM3 (show IFITM3 Proteins) specifically antagonize the HIV-1 envelope glycoprotein (Env (show ERVW-1 Proteins)), thereby inhibiting viral infection.

  2. G3BP1 (show G3BP1 Proteins), G3BP2 (show G3BP2 Proteins) and CAPRIN1 are required for translation of interferon (show IFNA Proteins) stimulated mRNAs and are targeted by a dengue virus non-coding RNA.

  3. Incorporation of IFITM1 (show IFITM1 Proteins), IFITM2 and IFITM3 (show IFITM3 Proteins) into HIV-1 virions impair viral fusion and spread.

  4. Host IFITM3 (show IFITM3 Proteins),IFITM2 and IFITM1 (show IFITM1 Proteins) facilitate morphogenesis of the human cytomegalovirus assembly.

  5. Although their inhibitory activities were modest when compared to that of tetherin (show BST2 Proteins), IFITMs, but not tetherin (show BST2 Proteins), directly reduced the expression of HIV-1 proteins including Gag, Vif (show BTG1 Proteins) and Nef.

  6. Authors show that interferon-induced transmembrane protein 1 (IFITM-1 (show IFITM1 Proteins)), IFITM-2, and IFITM-3 (show IFITM3 Proteins) exhibit a broad spectrum of antiviral activity against several members of the Bunyaviridae family.

  7. IFITM1 (show IFITM1 Proteins), IFITM2, and IFITM3 (show IFITM3 Proteins) inhibit HIV-1 replication through interfering with virus entry.

  8. IFITM2 and IFITM3 (show IFITM3 Proteins), disrupted early steps (entry and/or uncoating) of the viral infection, viperin, ISG20 (show ISG20 Proteins), and double-stranded-RNA-activated protein kinase (show EIF2AK2 Proteins), inhibited steps in west nile virus and dengue virus viral proteins and/or RNA biosynthesis.

  9. Single Nucleotide Polymorphisms in 1-8D is associated with neoplasms.

IFITM2 Protein Profile

Protein Summary

IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Gene names and symbols associated with IFITM2

  • interferon induced transmembrane protein 2 (IFITM2)
  • interferon induced transmembrane protein 2 (Ifitm2)
  • 1-8D protein
  • DSPA2c protein
  • fragilis3 protein
  • Ifitm3l protein
  • Ifitml protein
  • mil-3 protein

Protein level used designations for IFITM2

dispanin subfamily A member 2c , interferon-induced transmembrane protein 2 , interferon-inducible protein 1-8D , fragilis R , fragilis protein 3 , interferon induced transmembrane protein, like , interferon induced transmembrane protein 2 (1-8D) , interferon-inducible protein 16

GENE ID SPECIES
10581 Homo sapiens
80876 Mus musculus
114709 Rattus norvegicus
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