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IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. Additionally we are shipping Interferon Regulatory Factor 2 Proteins (18) and Interferon Regulatory Factor 2 Kits (2) and many more products for this protein.
Showing 10 out of 128 products:
Human Polyclonal IRF2 Primary Antibody for EIA, WB - ABIN952947
Lace, Anson, Haugen, Turek: Interferon regulatory factor (IRF)-2 activates the HPV-16 E6-E7 promoter in keratinocytes. in Virology 2010
Show all 3 references for ABIN952947
Human Polyclonal IRF2 Primary Antibody for ELISA, WB - ABIN184810
Harada, Kitagawa, Tanaka, Yamamoto, Harada, Ishihara, Taniguchi: Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2. in Science (New York, N.Y.) 1993
Show all 2 references for ABIN184810
Human Polyclonal IRF2 Primary Antibody for WB - ABIN655172
Daley, Lemire, Akhabir, Chan-Yeung, He, McDonald, Sandford, Stefanowicz, Tripp, Zamar, Bosse, Ferretti, Montpetit, Tessier, Becker, Kozyrskyj, Beilby, McCaskie, Musk, Warrington, James, Laprise, Palmer, Paré, Hudson: Analyses of associations with asthma in four asthma population samples from Canada and Australia. in Human genetics 2009
Show all 2 references for ABIN655172
Chicken Polyclonal IRF2 Primary Antibody for WB - ABIN2792666
Oshima, Nakamura, Namiki, Okada, Tsuchiya, Okamoto, Yamazaki, Yokota, Aida, Yamaguchi, Kanai, Handa, Watanabe: Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells. in Molecular and cellular biology 2004
Cow (Bovine) Polyclonal IRF2 Primary Antibody for WB - ABIN374254
Liljeroos, Vuolteenaho, Rounioja, Henriques-Normark, Hallman, Ojaniemi: Bacterial ligand of TLR2 signals Stat activation via induction of IRF1/2 and interferon-alpha production. in Cellular signalling 2008
It might play as a tumor suppressor by regulating P53 (show TP53 Antibodies) signaling in gastric cancer.
the association of IRF2 with susceptibility to systemic lupus erythematosus
Data suggest that interferon (show IFNA Antibodies) regulatory factors 1 and 2 (IRF1 (show IRF1 Antibodies) and IRF2) may serve as potential targets of therapy.
miR (show MLXIP Antibodies)-221 directly inhibits the expression of SOCS3 (show SOCS3 Antibodies) and IRF2.
KGF (show FGF7 Antibodies) could up-regulate IL-7 (show IL7 Antibodies) expression through the STAT1 (show STAT1 Antibodies)/IRF-1 (show IRF1 Antibodies), IRF-2 signaling pathway, which is a new insight in potential effects of KGF (show FGF7 Antibodies) on the intestinal mucosal immune system.
IFN regulatory factor 2 (Irf2) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3 (show SPINK1 Antibodies)
IRF2 overexpression protects against I/R injury by decreasing IRF1 (show IRF1 Antibodies)-dependent injury and may represent a novel therapeutic strategy.
The results suggested that distinct markers in IRF2 may be associated with atopic dermatitis and eczema herpeticum (which may depend upon ethnic ancestry) and genetic variants in IRF2 may contribute to an abnormal immune response to herpes simplex virus.
these results suggest that IRF-2 plays an important role in the tumorigenesis of pancreatic cancer and down-regulation of IRF-2 would be a new treatment target for pancreatic cancer.
IRF-2 activates the HPV-16 P97 (show EIF4G2 Antibodies) promoter in vivo.
Chimeric IRF-2 binds with IRF (show TRIM63 Antibodies)-E motif and VREbeta but not with VREalpha1.
IFN regulatory factor 2 (Irf2) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3
These results revealed a multi-faceted role of IRF-2 in the function of B cells, particularly B2 cells, through regulating proliferation in an IFNAR (show IFNAR1 Antibodies)-dependent manner and antibody production via up-regulation of Blimp-1 (show PRDM1 Antibodies).
In mice doubly deficient forIRF-2 and CD1d (show CD1D Antibodies), the overall memory phenotype T cell population is contrastingly enlarged.
IRF2 regulates exocytosis in pancreatic acinar cells; defects in this process might be involved in the early phases of acute pancreatitis.
Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells.
Irf2 has an important role in vitro in the regulation of COX-2 (show COX2 Antibodies) expression by LPS (show TLR4 Antibodies).
IRF-2 is acetylated in a cell growth-dependent manner, which enables it to contribute to transcription of cell growth-regulated promoters
IRF-2 is a critical transacting factor that regulates in vivo responses to lipopolysaccharide, with a novel anti-apoptotic role.
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
regulatory factor 2
, interferon responsive factor 2
, interferon regulatory factor 2b