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Interferon Related Developmental Regulator 1 Proteins (IFRD1)

IFRD1 is an immediate early gene that encodes a protein related to interferon-gamma. Additionally we are shipping Interferon Related Developmental Regulator 1 Antibodies (28) and Interferon Related Developmental Regulator 1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IFRD1 3475 O00458
IFRD1 15982 P19182
IFRD1 29596 P20695
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Top Interferon Related Developmental Regulator 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,259.67
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,263.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

IFRD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Interferon Related Developmental Regulator 1 (IFRD1) Interaction Partners

Human Interferon Related Developmental Regulator 1 (IFRD1) interaction partners

  1. rs7817 polymorphism associated with nasal polyposis in cystic fibrosis (show S100A8 Proteins) patients

  2. study reveals an EGFR (show EGFR Proteins)-IFRD1-mediated viral immune evasion mechanism, which can also be exploited by cancer cells

  3. PC4 plays essential roles in the transition step from transcription initiation to elongation by binding to melted DNA in collaboration with TFIIEbeta.

  4. Studied the association between IFRD1 polymorphisms and gastric cancer in a Chinese population.

  5. IFRD1 expression is systemically up-regulated in CF neutrophils, is linked to the production of ROS (show ROS1 Proteins), and is modulated by chemokines in CF airway fluids, depending on the IFRD1 genotype.

  6. This work provides evidence for the first time of reduced level of IFRD1 protein in murine and human F508del-CFTR (show CFTR Proteins) airway epithelial cell models.

  7. IFRD1 is a target gene of the BACH1 (show BACH1 Proteins) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 Proteins) 293 cells.

  8. This reference shows the cloning and the sequence of the original IFRD1 homolog isolated in rat as nerve growth factor-inducible immediate early (show JUN Proteins) gene (named PC4).

  9. IFRD1 is an inducer of skeletal muscle regeneration and of satelli (show MYOD1 Proteins)te cell amplification, by regulating MyoD and NF-kB.

  10. Identification of PC4/IFRD1 as a coactivator of MyoD (show MYOD1 Proteins), a key master gene of muscle development.

Mouse (Murine) Interferon Related Developmental Regulator 1 (IFRD1) interaction partners

  1. High-fat diet feeding in the setting of tis7 deletion resulted in postresection anastomotic inflammation and small bowel obstruction.

  2. TIS7 predominantly interacted with beta-catenin (show CTNNB1 Proteins) in the nucleus.

  3. This work provides evidence for the first time of reduced level of IFRD1 protein in murine and human F508del-CFTR (show CFTR Proteins) airway epithelial cell models.

  4. PC4 plays a role in muscle differentiation by controlling the MyoD (show MYOD1 Proteins) pathway through multiple mechanisms, and as such, it positively regulates regenerative myogenesis.

  5. altered postresection adaptive responses of Tis7 knockout mice in short bowel syndrome model; results suggest a novel physiologic function for Tis7 in gut (show GUSB Proteins) as global regulator of lipid absorption/metabolism and epithelial cell proliferation

  6. TIS7 protein interacts with several proteins of the SIN3 complex (mSin3B, HDAC1 (show HDAC1 Proteins), N-CoR (show NCOR1 Proteins) and SAP30 (show SAP30 Proteins). TIS7 is a transcriptional co-repressor affecting expression of specific genes in a HDAC (show HDAC3 Proteins)-activity-dependent manner during cell fate decisions.

  7. Results suggest that TIS7 is not essential for mouse development but plays a novel regulatory role during adult muscle regeneration.

  8. TIS7 is a unique mediator of nutrient absorptive and metabolic adaptation following gut (show GUSB Proteins) resection

  9. TIS7, a negative regulator of transcriptional activity, represses expression of OPN (show SPP1 Proteins) and beta-catenin (show CTNNB1 Proteins)/Tcf-4 (show TCF4 Proteins) target genes

  10. TIS7 inhibits CRABP II (show CRABP2 Proteins) expression during axonal regeneration, thereby modulating retinoic acid signalling. Hence, neurite initiation and branching are regulated by a negative feedback mechanism involving TIS7 and CRABP II (show CRABP2 Proteins).

Interferon Related Developmental Regulator 1 (IFRD1) Protein Profile

Protein Summary

This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with IFRD1

  • interferon-related developmental regulator 1 (ifrd1)
  • interferon-related developmental regulator 1 (IFRD1)
  • interferon-related developmental regulator 1 (Ifrd1)
  • Ifnl protein
  • IFR1 protein
  • im:7067566 protein
  • Pc4 protein
  • si:dkey-192l17.2 protein
  • Tis7 protein
  • wu:fi35f04 protein
  • wu:fj67a06 protein
  • zgc:154080 protein

Protein level used designations for IFRD1

12-O-tetradecanoylphorbol-13-acetate-induced sequence 7 , TPA induced sequence 7 , nerve growth factor-inducible protein PC4 , pheochromocytoma cell-4 , TPA-induced sequence 7 , IRPR

GENE ID SPECIES
555178 Danio rerio
494857 Xenopus laevis
395226 Gallus gallus
3475 Homo sapiens
482408 Canis lupus familiaris
493185 Sus scrofa
541283 Bos taurus
15982 Mus musculus
29596 Rattus norvegicus
702624 Macaca mulatta
463663 Pan troglodytes
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