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IFNGR2 (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Additionally we are shipping IFNGR2 Proteins (6) and and many more products for this protein.
Showing 10 out of 105 products:
Human Polyclonal IFNGR2 Primary Antibody for IF (p), IHC (p) - ABIN749483
Kunis, Baruch, Rosenzweig, Kertser, Miller, Berkutzki, Schwartz: IFN-?-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair. in Brain : a journal of neurology 2013
Show all 2 references for ABIN749483
Human Polyclonal IFNGR2 Primary Antibody for WB - ABIN2782679
Jin, Kim, Kim, Baek, Kang, Yeo, Lee: Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53. in Biochemical and biophysical research communications 2008
Human Polyclonal IFNGR2 Primary Antibody for FACS, IHC (p) - ABIN652277
Kotenko, Izotova, Pollack, Mariano, Donnelly, Muthukumaran, Cook, Garotta, Silvennoinen, Ihle: Interaction between the components of the interferon gamma receptor complex. in The Journal of biological chemistry 1995
Myeloid cell IFNGR2 deficiency does not affect atherosclerosis development in LDLR (show LDLR Antibodies) knockout mice.
IFN-gammaR2 T168N mutant diffusion is confined by distinct actin nanodomains where conformational changes required for JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) activation by IFN-gamma (show IFNG Antibodies) could not occur. Removing IFN-gammaR2 T168N-bound galectins restored lateral diffusion in lipid nanodomains and JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling in patient cells, whereas adding galectins impaired these processes in control cells.
Statistical analyses revealed that four genetic variants in IFNGR1 (show IFNGR1 Antibodies) were marginally associated with the risk of Tuberculosis (P = 0.02-0.04), while other single nucleotide polymorphisms in IFNGR1 (show IFNGR1 Antibodies) and IFNGR2 did not exhibit any associations
The variability of potentially important functional polymorphic variants of the IFNG (show IFNG Antibodies), IFNGR2 and NEIL2 (show NEIL2 Antibodies) genes was characterized in representatives of four ethnic groups living in the Siberian region.
Fatal hemophagocytic lymphohistiocytosis has been described in two unrelated pediatric patients with underlying IFNGR2 deficiency.
The expression of IFNGR2 was significantly higher in patients with RA compared with control subjects and was significantly higher in patients in whom radiographic damage was more severe.
We report a molecular study of the two known patients with autosomal recessive, partial interferon-gamma (show IFNG Antibodies) receptor (IFN-gammaR (show IFNGR1 Antibodies))2 deficiency
IFN-gammaR2-deficient monocytes induce a higher percentage of IL-17 (show IL17A Antibodies)(+) cells from both healthy and IFN-gammaR2-deficient CD4 (show CD4 Antibodies)(+) T cells.
IFNGR2 haploinsufficiency may underlie clinical tuberculosis in children living in areas of endemic disease.
JAK2 (show JAK2 Antibodies) is a critical factor that stabilizes IFN-gammaR2 surface expression in Th17 cells from AMS (show MAT1A Antibodies) patients, making them sensitive to IFN-gamma (show IFNG Antibodies).
We conclude that the polymorphisms of IFNGR2 may confer resistance to the TB development of newly infected individuals
Four SNPs in IFNGR2, IL12RB1 (show IL12RB1 Antibodies), IL12RB2 (show IL12RB2 Antibodies), and IL23R (show IL23R Antibodies) were found to be associated with the MAP infection status of the resource population.
SNPs in IFNG (show IFNG Antibodies), IFNGR1 (show IFNGR1 Antibodies) and R2, IL22 (show IL22 Antibodies), and IL22RA1 (show IL22RA1 Antibodies) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
IFN-gamma receptor 2
, interferon gamma receptor 2
, interferon gamma receptor accessory factor 1
, interferon gamma receptor accessory factor-1
, interferon gamma receptor beta chain
, interferon gamma transducer 1