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anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) Antibodies

IFIT1 encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. Additionally we are shipping IFIT1 Proteins (6) and IFIT1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IFIT1 294090  
IFIT1 3434 P09914
IFIT1 15957 Q64282
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Top anti-IFIT1 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-IFIT1 Antibody  Positive Control: Lane1:341 µg human Huh7, Lane2: 041 µg human Huh7+IFNB stimulated Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondry  Antibody Dilution: 1:0000Submitted by: Takeshi Saito, USC Keck School of Medicine WB Suggested Anti-IFIT1 AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Stomach 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from LOVO cells, using IFIT1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Western Blot analysis of IFIT1 expression in transfected 293T cell line by IFIT1 MaxPab polyclonal antibody.Lane 1: IFIT1 transfected lysate(55.40 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of IFIT1 expression in transfected 293T cell line by IFIT1 MaxPab polyclonal antibody.Lane 1: IFIT1 transfected lysate(52.58 KDa).Lane 2: Non-transfected lysate. IFIT1 MaxPab polyclonal antibody. Western Blot analysis of IFIT1 expression in Jurkat. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-IFIT1 mouse monoclonal antibody. (ABIN2453167, Dilution 1:50) Immunohistochemical staining of paraffin-embedded liver tissue using anti-IFIT1 mouse monoclonal antibody. (ABIN2453167, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Rabbit Un-conjugated WB WB Image Sample(30 μg of whole cell lysate) A:HeLa S3, 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

IFIT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)
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Human , , ,
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Mouse (Murine)
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Top referenced anti-IFIT1 Antibodies

  1. Human Polyclonal IFIT1 Primary Antibody for WB - ABIN516835 : Ikegame, Takeda, Ohno, Nakatsu, Nakanishi, Yanagi: Both RIG-I and MDA5 RNA helicases contribute to the induction of alpha/beta interferon in measles virus-infected human cells. in Journal of virology 2009 (PubMed)

  2. Human Polyclonal IFIT1 Primary Antibody for WB - ABIN516836 : Hsu, Lin, Sheu, Shieh, Chen, Lai, Tsai, Wan, Chen: A novel interaction between interferon-inducible protein p56 and ribosomal protein L15 in gastric cancer cells. in DNA and cell biology 2011 (PubMed)

More Antibodies against IFIT1 Interaction Partners

Human Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) interaction partners

  1. Data show that interferon (show IFNA Antibodies)-induced proteins with tetratricopeptide repeats 1 and 2 (IFIT1 and IFIT2 (show IFIT2 Antibodies)) contribute to the regulation of hepatitis B virus (HBV) replication, likely at both transcriptional and posttranscriptional steps.

  2. IFIT1 is not a dominant restriction factor against three different families of negative-sense RNA viruses.

  3. Reovirus T3D infection induced STAT-1, ISG-15, IFIT-1, Mx1, and IFIT-3 expression.

  4. The specificity of IFIT1 for 2'O-unmethylated RNA serves as potent antiviral mechanism against viruses lacking 2'O-methyltransferase activity and at the same time allows unperturbed progression of the antiviral program in infected cells.

  5. TLR4 (show TLR4 Antibodies) signaling, induced by LPS (show IRF6 Antibodies), increases the expression of melanoma differentiation-associated gene 5 (MDA5 (show IFIH1 Antibodies)) and interferon (show IFNA Antibodies)

  6. ISG56 may play a role in immune and inflammatory reactions induced by toll-like receptor 3 (show TLR3 Antibodies) signaling in human mesangial cells.

  7. Results indicate that miR (show MLXIP Antibodies)-203 is an interferon (show IFNA Antibodies)-inducible miRNA that can negatively regulate a number of cellular mRNAs, including an interferon (show IFNA Antibodies)-stimulated gene target, IFIT1/ISG56, by destabilizing its mRNA transcript.

  8. Data suggested that PIV5 mRNAs are methylated at the 2'-hydroxyl group and that ISG56/IFIT1 inhibits the translation of PIV5 mRNA by some unrecognized mechanism. Also ISG56/IFIT1 is primarily responsible for the IFN-induced inhibition of PIV5.

  9. crystal structures of human IFIT5, its complex with PPP-RNAs, and an amino-terminal fragment of IFIT1

  10. Hepatitis C virus infection suppresses the upregulation of a subset of effector molecules, including ISG56 and IFITM1 (show IFITM1 Antibodies).

Mouse (Murine) Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) interaction partners

  1. Data suggest that, with up-regulation of IFIT1, alphaviruses (Venezuelan equine encephalitis virus; Chikungunya virus) with wild-type 5' untranslated regions are inducers of type I IFN (interferon (show IFNA Antibodies)), suggesting a new mechanism of type I IFN induction.

  2. Targeted expression of Ifit1 in hepatocytes protects mice from lipopolysaccharide and D-galactosamine induced lethal hepatitis.

  3. IFIT1 is not a dominant restriction factor against three different families of negative-sense RNA viruses.

  4. The specificity of IFIT1 for 2'O-unmethylated RNA serves as potent antiviral mechanism against viruses lacking 2'O-methyltransferase activity and at the same time allows unperturbed progression of the antiviral program in infected cells.

  5. Thus, Ifit1 inhibits replication of MTase (show DNMT1 Antibodies)-defective Japanese encephalitis virus by inhibiting mRNA translation through direct binding to mRNA 5' structures.

  6. Study identified Ifit1 as an important innate immune bottleneck.

  7. results suggest that virulent strains of West Nile virus have largely evaded the antiviral effects of Ifit1, and viral mutants lacking 2'-O methylation are controlled in vivo by Ifit1-dependent and -independent mechanisms in different cell types

  8. IFIT1 bound PPP-RNA antagonizes viruses by sequestering specific viral nucleic acids.

  9. Under some stressful stimulations IFIT1 may participate in cell death pathways by interaction with eEF1A (show EEF1A2 Antibodies).

  10. block different functions of eIF3 (show EIF3A Antibodies) by binding to its different subunits.

IFIT1 Antigen Profile

Protein Summary

This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Gene names and symbols associated with IFIT1

  • interferon-induced protein with tetratricopeptide repeats 1-like B (Ifit1lb) antibody
  • interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) antibody
  • interferon-induced protein with tetratricopeptide repeats 1 (ifit1) antibody
  • interferon-induced protein with tetratricopeptide repeats 1 (Ifit1) antibody
  • C56 antibody
  • DKFZp469C2331 antibody
  • G10P1 antibody
  • Garg16 antibody
  • IFI-56 antibody
  • IFI-56K antibody
  • Ifi56 antibody
  • IFIT-1 antibody
  • Ifit1 antibody
  • IFNAI1 antibody
  • ISG56 antibody
  • P56 antibody
  • RNM561 antibody

Protein level used designations for IFIT1

interferon-induced protein with tetratricopeptide repeats 1 , interferon-induced protein with tetratricopeptide repeats 5-like , interferon-induced protein with tetratricopeptide repeats 1-like , interferon, alpha-inducible protein (MW 56kD) , interferon-induced 56 kDa protein , interferon-inducible mRNA 561 , GARG-16 , IFI-56K , IFIT-1 , glucocorticoid-attenuated response gene 16 protein , glucocorticoid-attenuated response gene 16 product , interferon-induced protein with tetratricopeptide repeats 1-like protein

GENE ID SPECIES
294090 Rattus norvegicus
450587 Pan troglodytes
488947 Canis lupus familiaris
495383 Xenopus laevis
695683 Macaca mulatta
100058990 Equus caballus
100139670 Bos taurus
100173806 Pongo abelii
100216071 Xenopus (Silurana) tropicalis
100406756 Callithrix jacchus
100475782 Ailuropoda melanoleuca
100585530 Nomascus leucogenys
3434 Homo sapiens
15957 Mus musculus
56824 Rattus norvegicus
Selected quality suppliers for anti-IFIT1 (IFIT1) Antibodies
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