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Interferon-Induced Protein with Tetratricopeptide Repeats 2 Proteins (IFIT2)

IFIT2 encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Additionally we are shipping Interferon-Induced Protein with Tetratricopeptide Repeats 2 Antibodies (56) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IFIT2 15958 Q64112
IFIT2 3433 P09913
Rat IFIT2 IFIT2 294091  
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Top Interferon-Induced Protein with Tetratricopeptide Repeats 2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
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HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Cricetulus griseus His tag   1 mg Log in to see 56 to 66 Days
$3,314.67
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HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
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IFIT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) Interaction Partners

Mouse (Murine) Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) interaction partners

  1. the mechanism for the observed differential induction of the mouse Ifit1 (show IFIT1 Proteins), Ifit2, and Ifit3 genes in B cells and demonstrated that the repressive effect of the transcription factor interferon regulatory factor 8 (IRF8 (show IRF8 Proteins)), which is highly expressed in B cells, played an essential role in this regulation.

  2. These results indicate that high Sendai virus replication in the lungs of infected Ifit2(-/-) mice cooperates with elevated IFN-beta (show IFNB1 Proteins) induction to cause disease.

  3. Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus.

  4. Ifit2 is a positive regulator of IFN-alpha (show IFNA Proteins)/beta expression during mouse hepatitis virus induced encephalitis.

  5. IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS (show TLR4 Proteins))-induced TNF-alpha (show TNF Proteins) secretion and LPS (show TLR4 Proteins)-induced endotoxin shock.

  6. These results suggest that Ifit2 restricts West Nile virus infection and pathogenesis in different tissues in a cell type-specific manner.

  7. results indicate that in the brain, but not in other organs, Ifit2 is a major mediator of IFN's protective effect against VSV

  8. Inhibitor of kappaB kinase epsilon (IKK(epsilon (show IKBKE Proteins))), STAT1 (show STAT1 Proteins), and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection.

  9. Our findings provide the first evidence of a differential pattern of expression of ISG54 and ISG56 (show IFIT1 Proteins) genes by IFN-alpha (show IFNA Proteins) and IFN-beta (show IFNB1 Proteins).

  10. IFIT-2 may affect selectively LPS (show TLR4 Proteins) induced protein expression probably by regulation at different posttranscriptional levels

Human Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) interaction partners

  1. there is a positive feedback loop between phosphorylated STAT1 and ISG56, ISG54 or ISG60.

  2. Data show that interferon (show IFNA Proteins)-induced proteins with tetratricopeptide repeats 1 and 2 (IFIT1 (show IFIT1 Proteins) and IFIT2) contribute to the regulation of hepatitis B virus (HBV) replication, likely at both transcriptional and posttranscriptional steps.

  3. Data shows that IFIT2 expression is downregulated in adenocarcinoma of gastric esophageal junction cells; its ectopic expression leads to cell apoptosis, suggesting its role as a tumor suppressor.

  4. 1p31 SFRS11 v

  5. IFIT2, a protein responsible for interferon (show IFNA Proteins) stimulation, may prevent oral squamous cell carcinoma (OSCC) metastasis and serve as a valuable prognostic marker.

  6. ISG54 binds specifically to some RNAs, such as adenylate uridylate (AU)-rich RNAs, with or without 5' triphosphorylation.

  7. Inhibitor of kappaB kinase epsilon (IKK(epsilon (show IKBKE Proteins))), STAT1 (show STAT1 Proteins), and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection.

  8. The expression of OASL (show OASL Proteins) and IFIT2 was significantly higher in SLE patients than in controls.

  9. role of ISG54 in the induction of apoptosis via a mitochondrial pathway shedding new light on the mechanism by which IFN elicits anti-viral and anti-cancer effects

  10. SRp54 (show SRP54 Proteins) interacts with a purine-rich element tau in exon 10 and antagonizes Tra2beta (show TRA2B Proteins), an SR-domain-containing protein that enhances exon 10 inclusion.

Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) Protein Profile

Protein Summary

This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.

Gene names and symbols associated with IFIT2

  • interferon-induced protein with tetratricopeptide repeats 2 (ifit2)
  • interferon-induced protein with tetratricopeptide repeats 2 (IFIT2)
  • interferon-induced protein with tetratricopeptide repeats 2 (LOC100341555)
  • interferon-induced protein with tetratricopeptide repeats 2 (Ifit2)
  • serine/arginine-rich splicing factor 11 (SRSF11)
  • AV302338 protein
  • cig42 protein
  • dJ677H15.2 protein
  • DKFZp468G198 protein
  • G10P2 protein
  • GARG-39 protein
  • IFI-54 protein
  • IFI-54K protein
  • IFI54 protein
  • IFIT-2 protein
  • ISG-54 K protein
  • ISG-54K protein
  • ISG54 protein
  • NET2 protein
  • p54 protein
  • SFRS11 protein
  • wu:fb58d07 protein

Protein level used designations for IFIT2

interferon-induced protein with tetratricopeptide repeats 2 , GARG-39 , IFI-54K , IFIT-2 , glucocorticoid-attenuated response gene 39 protein , interferon-induced 54 kDa protein , Interferon, alpha-inducible protein (MW 54kD) , interferon-induced protein 54 , SR splicing factor 11 , arginine-rich 54 kDa nuclear protein , splicing factor p54 , splicing factor, arginine/serine-rich 11

GENE ID SPECIES
322336 Danio rerio
450585 Pan troglodytes
479183 Canis lupus familiaris
527528 Bos taurus
695452 Macaca mulatta
100173024 Pongo abelii
100341555 Oryctolagus cuniculus
100584973 Nomascus leucogenys
15958 Mus musculus
3433 Homo sapiens
294091 Rattus norvegicus
9295 Homo sapiens
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