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IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Additionally we are shipping IFITM1 Proteins (8) and many more products for this protein.
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Human Polyclonal IFITM1 Primary Antibody for WB - ABIN1881445
Yang, Chen, Lin, Yu, Liu, Wang, Liu, Chen et al.: Nickel catalysts bearing bidentate alpha-aminoaldimines for ethylene polymerization--independent and cooperative structure/reactivity relationship resulting from unsymmetric square planar... in Dalton transactions (Cambridge, England : 2003) 2009
Show all 3 references for ABIN1881445
Human Polyclonal IFITM1 Primary Antibody for EIA, IF - ABIN783647
Deblandre, Marinx, Evans, Majjaj, Leo, Caput, Huez, Wathelet: Expression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growth. in The Journal of biological chemistry 1995
the importance of the C-terminal region of IFITM1 in modulating the antiviral function through controlling protein subcellular localization.
Suggest that IFITM1 promotes the aggressiveness of colorectal cancer cells via caveolin-1 (show CAV1 Antibodies) signaling.
Incorporation of IFITM1, IFITM2 (show IFITM2 Antibodies) and IFITM3 (show IFITM3 Antibodies) into HIV-1 virions impair viral fusion and spread.
Host IFITM3 (show IFITM3 Antibodies),IFITM2 (show IFITM2 Antibodies) and IFITM1 facilitate morphogenesis of the human cytomegalovirus assembly.
IFITM1 could be a novel metastasis-promoting gene that enhances the metastatic phenotype in ovarian cancer via epigenetic transcriptional regulation.
IFITM1 is a potential valuable addition to immunohistochemical panels used in the diagnosis of cellular mesenchymal uterine tumors.
Results suggest that the g.-1920G>A polymorphism in interferon (show IFNA Antibodies) inducible transmembrane protein 1 (show TMEM1 Antibodies) (IFITM1) may be associated with susceptibility to ulcerative colitis (UC).
IFITM1 is essential for the formation of functional blood vessels and stabilizes EC-EC (show QPCT Antibodies) interactions during endothelial lumen formation by regulating tight junction assembly.
Although their inhibitory activities were modest when compared to that of tetherin (show BST2 Antibodies), IFITMs, but not tetherin (show BST2 Antibodies), directly reduced the expression of HIV-1 proteins including Gag, Vif (show BTG1 Antibodies) and Nef.
Authors show that interferon-induced transmembrane protein 1 (IFITM-1), IFITM-2 (show IFITM2 Antibodies), and IFITM-3 (show IFITM3 Antibodies) exhibit a broad spectrum of antiviral activity against several members of the Bunyaviridae family.
Ifitm3 (show IFITM3 Antibodies) plays a role in mouse primordial germ cell homing and repulsion by enhancing the regionalization of PGCs.
Ifitm3 (show IFITM3 Antibodies) does not impact on the restriction or pathogenesis of bacterial (Salmonella typhimurium, Citrobacter rodentium, Mycobacterium tuberculosis) or protozoan (Plasmodium berghei) pathogens, despite in vitro evidence.
results suggest that modification of Tyr (show TYR Antibodies)(20) may serve in a cellular checkpoint controlling IFITM3 (show IFITM3 Antibodies) trafficking and degradation and demonstrate the complexity of posttranslational regulation of IFITM3 (show IFITM3 Antibodies)
Interferon-induced transmembrane protein 3 is a type II transmembrane protein.
results revealed diverse, yet consistent, profiles of IFITM3 (show IFITM3 Antibodies) localization throughout the gastrula
Induction of IFITM3 (show IFITM3 Antibodies) expression in astrocytes leads to brain dysfunction by impairing neurite development and other non-cell autonomous effects such as increasing mRNA levels of inflammatory cytokines.
Palmitoylation of IFITM1 regulates protein stability by preventing proteasomal degradation, and modification of the nonconserved cysteine at the IFITM1 C terminus supports an intramembrane topology with implications for anti-influenza A virus activity.
Jin Chai antiviral capsule exerts antiviral effects against influenza virus by raised expression of IFITM3 (show IFITM3 Antibodies).
the fact that IFITM1 can function as a negative regulator of cell proliferation, and because the gene maps to chromosome band 11p15.5, previously associated with NSCLC, it is likely that IFITM1 in man has a key role in tumor formation
IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53- dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.
interferon induced transmembrane protein 1 (9-27)
, interferon-induced transmembrane protein 1
, interferon induced transmembrane protein 1
, dispanin subfamily A member 2a
, interferon-induced protein 17
, interferon-inducible protein 9-27
, leu-13 antigen
, fragilis protein 2
, ifitm-like protein 2
, interferon induced transmembrane protein 2 like
, dispanin subfamily A member 2b
, fragilis protein
, ifitm-like protein 1
, interferon-induced transmembrane protein 3
, interferon-inducible protein 15