Interferon-Induced Transmembrane Protein 1 Proteins (IFITM1)

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Additionally we are shipping IFITM1 Antibodies (105) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IFITM1 8519 P13164
IFITM1 68713 Q9D103
Rat IFITM1 IFITM1 293618  
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Top IFITM1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human GST tag Interferon-Induced Transmembrane Protein 1 (IFITM1) (AA 1-36) protein (GST tag) 1 mg Log in to see 60 to 71 Days
$1,842.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
$641.43
Details

IFITM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Interferon-Induced Transmembrane Protein 1 (IFITM1) Interaction Partners

Human Interferon-Induced Transmembrane Protein 1 (IFITM1) interaction partners

  1. IFITM1 and IFITM3 (show IFITM3 Proteins) inhibit Zika virus infection early in the viral life cycle.

  2. IFITM1 suppression blocks proliferation and invasion of aromatase (show CYP19A1 Proteins) inhibitor-resistant breast cancer in vivo by JAK (show JAK3 Proteins)/STAT1 (show STAT1 Proteins)-mediated induction of p21 (show CDKN1A Proteins).

  3. Compared with CD10 (show MME Proteins), IFITM1 has superior performance distinguishing endometrial stroma of adenomyosis from mesenchyma surrounding invasive endometrial adenocarcinoma.

  4. Overexpression of IFITM1 is associated with Oral Squamous Cell Carcinomas.

  5. High expression of IFITM1 is associated with poor prognosis of colorectal cancer.

  6. These findings indicate that overexpression of IFITM1 enhances the aggressive phenotype of triple-negative SUM149 IBC cells and that this effect is dependent on STAT2 (show STAT2 Proteins)/BRG1 (show SMARCA4 Proteins) interaction.

  7. the importance of the C-terminal region of IFITM1 in modulating the antiviral function through controlling protein subcellular localization.

  8. Suggest that IFITM1 promotes the aggressiveness of colorectal cancer cells via caveolin-1 (show CAV1 Proteins) signaling.

  9. Incorporation of IFITM1, IFITM2 (show IFITM2 Proteins) and IFITM3 (show IFITM3 Proteins) into HIV-1 virions impair viral fusion and spread.

  10. Host IFITM3 (show IFITM3 Proteins),IFITM2 (show IFITM2 Proteins) and IFITM1 facilitate morphogenesis of the human cytomegalovirus assembly.

Mouse (Murine) Interferon-Induced Transmembrane Protein 1 (IFITM1) interaction partners

  1. IFITM1 and IFITM3 (show IFITM3 Proteins) inhibit Zika virus infection early in the viral life cycle.

  2. ZMPSTE24 (show Zmpste24 Proteins) is a downstream effector of IFITM3 (show IFITM3 Proteins) and is important for interferon (show IFNA Proteins)-induced transmembrane antiviral activity.

  3. IFITM3 (show IFITM3 Proteins) represents a checkpoint regulator of antiviral immunity that controls cytokine production to restrict viral pathogenesis.

  4. Collectively, the data define an antiviral role for Ifitm3 (show IFITM3 Proteins) in restricting infection of multiple alphaviruses.

  5. Ifitm3 (show IFITM3 Proteins) plays a role in mouse primordial germ cell homing and repulsion by enhancing the regionalization of PGCs.

  6. the importance of the C-terminal region of IFITM1 in modulating the antiviral function through controlling protein subcellular localization.

  7. Ifitm3 (show IFITM3 Proteins) does not impact on the restriction or pathogenesis of bacterial (Salmonella typhimurium, Citrobacter rodentium, Mycobacterium tuberculosis) or protozoan (Plasmodium berghei) pathogens, despite in vitro evidence.

  8. results suggest that modification of Tyr (show TYR Proteins)(20) may serve in a cellular checkpoint controlling IFITM3 (show IFITM3 Proteins) trafficking and degradation and demonstrate the complexity of posttranslational regulation of IFITM3 (show IFITM3 Proteins)

  9. Interferon-induced transmembrane protein 3 (show IFITM3 Proteins) is a type II transmembrane protein (show SLC3A2 Proteins).

  10. results revealed diverse, yet consistent, profiles of IFITM3 (show IFITM3 Proteins) localization throughout the gastrula

IFITM1 Protein Profile

Protein Summary

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53- dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Gene names and symbols associated with IFITM1

  • interferon induced transmembrane protein 1 (9-27) (IFITM1)
  • interferon induced transmembrane protein 1 (IFITM1)
  • interferon induced transmembrane protein 1 (Ifitm1)
  • interferon induced transmembrane protein 3 (Ifitm3)
  • 9-27 protein
  • 1110004C05Rik protein
  • 1110036C17Rik protein
  • Cd225 protein
  • Cdw217 protein
  • DSPA2a protein
  • DSPA2b protein
  • Fgls protein
  • IFI17 protein
  • IP15 protein
  • LEU13 protein
  • mil-1 protein
  • Mil-2 protein
  • Mil2 protein

Protein level used designations for IFITM1

interferon induced transmembrane protein 1 (9-27) , interferon-induced transmembrane protein 1 , interferon induced transmembrane protein 1 , dispanin subfamily A member 2a , interferon-induced protein 17 , interferon-inducible protein 9-27 , leu-13 antigen , fragilis protein 2 , fragilis2 , ifitm-like protein 2 , interferon induced transmembrane protein 2 like , dispanin subfamily A member 2b , fragilis protein , ifitm-like protein 1 , interferon-induced transmembrane protein 3 , interferon-inducible protein 15

GENE ID SPECIES
100455800 Pongo abelii
100526663 Pan troglodytes
8519 Homo sapiens
68713 Mus musculus
293618 Rattus norvegicus
66141 Mus musculus
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