anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) Antibodies

The protein encoded by IFITM3 is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Additionally we are shipping Interferon-Induced Transmembrane Protein 3 Kits (8) and Interferon-Induced Transmembrane Protein 3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IFITM3 66141 Q9CQW9
IFITM3 10410 Q01628
IFITM3 361673 P26376
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Top anti-Interferon-Induced Transmembrane Protein 3 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB   0.4 mL Log in to see 12 to 15 Days
$375.38
Details
Human Mouse Un-conjugated WB Western Blot analysis of IFITM3 expression in transfected 293T cell line by IFITM3 MaxPab polyclonal antibody.Lane 1: IFITM3 transfected lysate(14.63 KDa).Lane 2: Non-transfected lysate. IFITM3 MaxPab polyclonal antibody. Western Blot analysis of IFITM3 expression in human placenta. 50 μL Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, IF, WB Western Blot (WB) analysis of specific cells using IFITM3 Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HepG2/HeLa cells, using IFM3 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of MCF7 cells, using IFM3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB IFITM3 monoclonal antibody (M01), clone 4C8-1B10 Western Blot analysis of IFITM3 expression in Hela . Detection limit for recombinant GST tagged IFITM3 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of IFITM3 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of IFITM3 expression in HEK293T (A), HeLa (B), Raw264.7 (C), H9C2 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated SimWes, WB Simple Western: IFITM3/Fragilis Antibody [ABIN269697] - Simple Western lane view shows a specific band for Fragilis in 0.5 mg/ml of NIH-3T3 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Western Blot: IFITM3/Fragilis Antibody [ABIN269697] - Analysis of Fragilis in mouse ES lysate in the (1) absence and (2) presence of immunizing peptide and in mouse NIH3T3 lysate in the (3) absence and (4) presence of immunizing peptide using Fragilis antibody at 1 ug/ml. 0.1 mg Log in to see 7 to 9 Days
$317.63
Details
Human Rabbit Un-conjugated IP, WB IFITM3 MaxPab rabbit polyclonal antibody. Western Blot analysis of IFITM3 expression in human placenta. IFITM3 MaxPab rabbit polyclonal antibody. Western Blot analysis of IFITM3 expression in HepG2. 100 μL Log in to see 11 to 12 Days
$418.57
Details
Human Goat Un-conjugated ELISA, WB ABIN4902672 (1µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 16 Days
$353.68
Details

IFITM3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human
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Rat (Rattus)


Top referenced anti-Interferon-Induced Transmembrane Protein 3 Antibodies

  1. Human Monoclonal IFITM3 Primary Antibody for ELISA, WB - ABIN564524 : Fan, Peng, Zhou, Qiu, Tang, Sun, Wang, Li, Le, Xie et al.: Gene-expression profiling in Chinese patients with colon cancer by coupling experimental and bioinformatic genomewide gene-expression analyses: identification and validation of IFITM3 as a biomarker ... in Cancer 2008 (PubMed)
    Show all 3 references for 564524

  2. Human Polyclonal IFITM3 Primary Antibody for WB - ABIN523801 : Jia, Pan, Ding, Rong, Liu, Geng, Qiao, Liang: The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization. in Journal of virology 2012 (PubMed)
    Show all 2 references for 523801

  3. Human Polyclonal IFITM3 Primary Antibody for EIA, WB - ABIN356685 : Tanaka, Yamaguchi, Tsoi, Lickert, Tam: IFITM/Mil/fragilis family proteins IFITM1 and IFITM3 play distinct roles in mouse primordial germ cell homing and repulsion. in Developmental cell 2005 (PubMed)

More Antibodies against Interferon-Induced Transmembrane Protein 3 Interaction Partners

Mouse (Murine) Interferon-Induced Transmembrane Protein 3 (IFITM3) interaction partners

  1. IFITM3 represents a checkpoint regulator of antiviral immunity that controls cytokine production to restrict viral pathogenesis.

  2. Collectively, the data define an antiviral role for Ifitm3 in restricting infection of multiple alphaviruses.

  3. Ifitm3 plays a role in mouse primordial germ cell homing and repulsion by enhancing the regionalization of PGCs.

  4. Ifitm3 does not impact on the restriction or pathogenesis of bacterial (Salmonella typhimurium, Citrobacter rodentium, Mycobacterium tuberculosis) or protozoan (Plasmodium berghei) pathogens, despite in vitro evidence.

  5. results suggest that modification of Tyr (show TYR Antibodies)(20) may serve in a cellular checkpoint controlling IFITM3 trafficking and degradation and demonstrate the complexity of posttranslational regulation of IFITM3

  6. Interferon-induced transmembrane protein 3 is a type II transmembrane protein.

  7. results revealed diverse, yet consistent, profiles of IFITM3 localization throughout the gastrula

  8. Induction of IFITM3 expression in astrocytes leads to brain dysfunction by impairing neurite development and other non-cell autonomous effects such as increasing mRNA levels of inflammatory cytokines.

  9. Jin Chai antiviral capsule exerts antiviral effects against influenza virus by raised expression of IFITM3.

  10. lung TRM cells were programmed to retain IFITM3 expression, which facilitated their survival and protection from viral infection during subsequent exposures

Human Interferon-Induced Transmembrane Protein 3 (IFITM3) interaction partners

  1. We failed to confirm an association between the rs12252_C allele of IFITM3 and influenza susceptibility in 2 cohorts of children.

  2. homozygous IFITM3 CC and TLR3 (show TLR3 Antibodies) CC genotypes showed significant independent associations with higher death risks in H7N9/H1N1pdm09 influenza in a large Chinese cohort

  3. We found evidence of a new association of rs34481144 with severe influenza in three cohorts characterized by different levels of influenza illness severity. rs34481144 is an expression quantitative trait locus (eQTL (show EQTN Antibodies)) for IFITM3, with the risk allele associated with lower mRNA expression. The risk allele was found to have decreased IRF3 (show IRF3 Antibodies) binding and increased CTCF (show CTCF Antibodies) binding in promoter-binding assays.

  4. IFITM3 rs12252 variant was associated with respiratory infection hospitalization but not specifically in patients infected with Influenza A(H1N1)pdm09.

  5. findings show that the sensitivity of influenza A viruses to the IFN-induced antiviral state and IFITM2 (show IFITM2 Antibodies) and IFITM3 proteins depends on the pH value at which the viral HA undergoes a conformational transition and mediates membrane fusion

  6. cell-extrinsic and cell-intrinsic factors including IFITM3 have roles in regulating the efficiency and kinetics of virus entry and fusion with target cells

  7. Key features of the HIV-1 envelope protein that are associated with viral resistance to the IFITM3 protein.

  8. The study demonstrates that the human pulmonary endothelium possesses intrinsic immunity to human influenza viruses, in part due to the constitutive expression of IFITM3 proteins.

  9. The present study identified the transcripts, which were affected by the downregulation of endogenous IFITM3 and the pathways they were involved in. These findings may lead to an improved understanding of the biological functions of IFITM3.

  10. there is one transmembrane helix in the human IFITM3 with a possible role in virus entry

Interferon-Induced Transmembrane Protein 3 (IFITM3) Antigen Profile

Protein Summary

The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined.

Gene names and symbols associated with IFITM3

  • Interferon-induced transmembrane protein 3 (ifm3) antibody
  • interferon induced transmembrane protein 3 (Ifitm3) antibody
  • interferon induced transmembrane protein 3 (IFITM3) antibody
  • 1-8U antibody
  • 1110004C05Rik antibody
  • Cd225 antibody
  • Cdw217 antibody
  • DSPA2b antibody
  • Fgls antibody
  • IP15 antibody
  • mil-1 antibody
  • rat8 antibody

Protein level used designations for IFITM3

Interferon-induced transmembrane protein 3 , dispanin subfamily A member 2b , fragilis protein , ifitm-like protein 1 , interferon-induced transmembrane protein 3 , interferon-inducible protein 15 , interferon-inducible protein 1-8U , interferon-inducible protein variant 10

GENE ID SPECIES
100305344 Oncorhynchus mykiss
66141 Mus musculus
10410 Homo sapiens
361673 Rattus norvegicus
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