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Interleukin 1 Receptor Accessory Protein-Like 1 Proteins (IL1RAPL1)

The protein encoded by IL1RAPL1 is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. Additionally we are shipping IL1RAPL1 Antibodies (18) and IL1RAPL1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL1RAPL1 11141 Q9NZN1
IL1RAPL1 331461  
IL1RAPL1 317553 P59824
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Top IL1RAPL1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 10 μg Log in to see 16 Days
$206.80
Details
HOST_Human Cells Mouse Fc Tag 10 μg Log in to see 16 Days
$206.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,898.50
Details
Yeast Pongo pygmaeus His tag   1 mg Log in to see 56 to 66 Days
$2,918.67
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,918.67
Details

IL1RAPL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) , ,
, ,
Rat (Rattus)

Top referenced IL1RAPL1 Proteins

  1. Human IL1RAPL1 Protein expressed in Human Cells - ABIN2002254 : Yoshida, Mishina: Zebrafish orthologue of mental retardation protein IL1RAPL1 regulates presynaptic differentiation. in Molecular and cellular neurosciences 2008 (PubMed)
    Show all 4 references for ABIN2002254

  2. Mouse (Murine) IL1RAPL1 Protein expressed in Human Cells - ABIN2008390 : Gambino, Pavlowsky, Béglé, Dupont, Bahi, Courjaret, Gardette, Hadjkacem, Skala, Poulain, Chelly, Vitale, Humeau: IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 3 references for ABIN2008390

More Proteins for Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1) Interaction Partners

Human Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1) interaction partners

  1. It was indicated that a defect in IL1RAPL1 that controls excitatory synapsis formation results in the excitation-inhibition balance affecting various cerebral functions.

  2. Novel IL1RAPL1 mutations associated with intellectual disability impair synaptogenesis.

  3. The interaction of the IL1RAPL1 family of proteins with PTPdelta and RhoGAP2 reveals a pathophysiological mechanism of cognitive impairment associated with a novel type of trans-synaptic signaling.

  4. The IL1RAPL1 gene is of interest as a candidate gene for autism spectrum disorder as mutations or deletions in the gene have previously been reported in individuals from families with ASD (show ARSD Proteins).

  5. Nearly all patients with deletions involving DAX1 (show NR0B1 Proteins), but not DMD (show DMD Proteins), had mental retardation if IL1RAPL1 was deleted. If ILIRAPLI & DMD (show DMD Proteins) were intact, the patients with DAX1 (show NR0B1 Proteins) deletions only rarely had normal development.

  6. Report confirms the role of the IL1RAPL1 gene in causing nonspecific mental retardation in males.

  7. DMD (show DMD Proteins) gene and its immediately distal neighbor, the 1.8 Mb IL1RAPL1 gene are abundantly expressed in normal brain but were dramatically underexpressed in every brain tumor cell line and xenograft.

  8. Combined data suggested that IL1RAPL1 affected human cognitive ability to some extent, especially the memory and concentration capability.

  9. The function of truncated IL1RAPL1 protein in an autistic female with Asperger syndrome is severely altered in hippocampal neurons, demonstrated by its effect on neurite outgrowth activity.

  10. IL1RAPL1 plays an important role in the etiology of X-linked mental retardation.

Mouse (Murine) Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1) interaction partners

  1. These results thus reveal the decoding mechanism of splice-insert signaling codes for synaptic differentiation induced by trans-synaptic adhesion between PTPdelta and IL1RAPL1/IL-1RAcP (show IL1RAP Proteins).

  2. These results suggest that IL1RAPL1 ablation resulted in spine density decrease and affected not only learning but also behavioural flexibility, locomotor activity and anxiety.

  3. It was indicated that a defect in IL1RAPL1 that controls excitatory synapsis formation results in the excitation-inhibition balance affecting various cerebral functions.

  4. IL1RAPL1 associated with mental retardation and autism regulates the formation and stabilization of glutamatergic synapses of cortical neurons through RhoA (show RHOA Proteins) signaling pathway.

  5. the results of this study suggested that constitutive absence of Il1rapl1 disrupts this balance, possibly explaining the deficit in LTP (show SCP2 Proteins) induction in vivo and the behavioral deficits observed in KO mice.

  6. results suggest that IL1RAPL1 mediates synapse formation through trans-synaptic interaction with PTPdelta.

  7. Absence of IL1RAPL1 causes a transient disinhibition of deep cerebellar nuclei neurons between postnatal days 10 and 14.

IL1RAPL1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.

Gene names and symbols associated with IL1RAPL1

  • interleukin 1 receptor accessory protein-like 1 (IL1RAPL1)
  • interleukin 1 receptor accessory protein-like 1 (Il1rapl1)
  • 6330532G10Rik protein
  • C030039N24 protein
  • IL1R8 protein
  • Il1rapl protein
  • MRX10 protein
  • MRX21 protein
  • MRX34 protein
  • OPHN4 protein
  • TIGIRR-2 protein

Protein level used designations for IL1RAPL1

interleukin 1 receptor accessory protein-like 1 , IL-1-RAPL-1 , IL-1RAPL-1 , IL1RAPL-1 , X-linked interleukin-1 receptor accessory protein-like 1 , interleukin 1 receptor-8 , interleukin-1 receptor accessory protein-like 1 , mental retardation, X-linked 10 , oligophrenin-4 , three immunoglobulin domain-containing IL-1 receptor-related 2

GENE ID SPECIES
100546693 Meleagris gallopavo
11141 Homo sapiens
427993 Gallus gallus
491800 Canis lupus familiaris
100154894 Sus scrofa
541298 Bos taurus
331461 Mus musculus
317553 Rattus norvegicus
450116 Pan troglodytes
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