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anti-Interleukin 10 Receptor, alpha (IL10RA) Antibodies

The protein encoded by IL10RA is a receptor for interleukin 10. Additionally we are shipping IL10RA Kits (18) and IL10RA Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL10RA 3587 Q13651
IL10RA 16154 Q61727
IL10RA 117539  
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Top anti-IL10RA Antibodies at antibodies-online.com

Showing 10 out of 203 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-IL10RA Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of IL10RA Antibody (Center) in MCF-7 cell line lysates (35ug/lane). IL10RA (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc cells, using IL-10R alpha (Phospho-Tyr496) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HepG2 cells, treated with Na2VO3 0.3nM 40', using IL-10R alpha (Ab-496) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using IL-10R alpha (Ab-496) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IF, WB Western blot analysis of IL10RA Antibody (Center) (ABIN652714) in MCF-7 cell line lysates (35 µg/lane). IL10RA (arrow) was detected using the purified polyclonal antibody. IL10RA Antibody (Center) (ABIN652714) flow cytometry analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rat PE FACS   100 Tests Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated WB   0.1 mL Log in to see 6 to 8 Days
$357.50
Details
Human Rat Un-conjugated FACS   0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Mouse Rat Un-conjugated FACS   0.25 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rat PE FACS Staining of human peripheral blood lymphocytes with RAT ANTI HUMAN CD210:RPE 100 Tests Log in to see 6 to 8 Days
$434.50
Details

IL10RA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-IL10RA Antibodies

  1. Mouse (Murine) Monoclonal IL10RA Primary Antibody for FACS - ABIN119864 : Asseman, Mauze, Leach, Coffman, Powrie: An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. in The Journal of experimental medicine 1999 (PubMed)
    Show all 4 references for ABIN119864

  2. Mouse (Murine) Monoclonal IL10RA Primary Antibody for FACS - ABIN119865 : Sundstedt, ONeill, Nicolson, Wraith: Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 3 references for ABIN119865

  3. Human Polyclonal IL10RA Primary Antibody for WB - ABIN616045 : Okwor, Liu, Beverley, Uzonna: Inoculation of killed Leishmania major into immune mice rapidly disrupts immunity to a secondary challenge via IL-10-mediated process. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 3 references for ABIN616045

  4. Human Monoclonal IL10RA Primary Antibody for FACS - ABIN119837 : Liu, de Waal Malefyt, Briere, Parham, Bridon, Banchereau, Moore, Xu: The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
    Show all 2 references for ABIN119837

  5. Human Polyclonal IL10RA Primary Antibody for FACS, IF - ABIN652714 : Jones, Logsdon, Josephson, Cook, Barry, Walter: Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

  6. Human Polyclonal IL10RA Primary Antibody for WB - ABIN2782131 : Gasche, Grundtner, Zwirn, Reinisch, Shaw, Zdanov, Sarma, Williams, Foxwell, Gangl: Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)

  7. Human Polyclonal IL10RA Primary Antibody for ELISA, WB - ABIN1531662 : Josephson, Logsdon, Walter: Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site. in Immunity 2001 (PubMed)

More Antibodies against IL10RA Interaction Partners

Human Interleukin 10 Receptor, alpha (IL10RA) interaction partners

  1. genetic association study in cohort of infants/children: Data suggest perianal fistulas are exhibited in patients with very early-onset inflammatory bowel disease with IL10 (show IL10 Antibodies) receptor mutations (IL10RA/B); prognosis and response to treatment are poor.

  2. IL-10Ralpha expression is post-transcriptionally regulated by miR (show MLXIP Antibodies)-15a, miR (show MLXIP Antibodies)-185, and miR (show MLXIP Antibodies)-211 in melanoma

  3. We also observed that BM-MSCs upregulated IL-10 (show IL10 Antibodies) secretion as well as the expression of its receptor CD210 on T cells, thus creating a loop favoring the expansion of IL-10 (show IL10 Antibodies)-producing T cells

  4. SNP3 polymorphism is associated with myocardial infarction; may generate some conformational rearrangements of the IL-10R1 receptor domain which affects IL-10 (show IL10 Antibodies) complex binding and alters its downstream signal

  5. High IL10RA expression is associated with diffuse large B-cell lymphoma.

  6. Data suggest that, compared with monocytes and macrophages, myeloid dendritic cells partially escape from IL-10 (show IL10 Antibodies)'s inhibitory mechanisms by downregulating IL-10R1.

  7. Inflammatory bowel disease (IBD) in infancy is phenotypically and genetically different disease entity from adult-onset or older child-onset IBD. It has a strong association with IL-10 (show IL10 Antibodies) receptor gene.

  8. IL10R1 loss-of-function A536/S138G polymorphism may contribute to recurrent pregnancy loss pathogenesis

  9. Very early onset inflammatory bowel disease associated with aberrant trafficking of IL-10R1 and cure by T cell replete haploidentical bone marrow transplantation.

  10. No evidence for an involvement of autoantibodies against IL-10 (show IL10 Antibodies) or IL-10R in the pathogenesis of inflammatory bowel disease could be established.

Mouse (Murine) Interleukin 10 Receptor, alpha (IL10RA) interaction partners

  1. loss of IL-10R signaling impaired the generation and function of anti-inflammatory intestinal and bone-marrow-derived macrophages and their ability to secrete IL-10 (show IL10 Antibodies).

  2. loss of IL-10 (show IL10 Antibodies) receptor expression impaired the critical conditioning of monocyte-derived macrophages and resulted in spontaneous development of severe colitis.

  3. Recent findings review how IL10 (show IL10 Antibodies)- and IL10R-dependent signaling modulates innate and adaptive immune responses in the murine intestine.

  4. Treatment of mice with rIFN-gamma was sufficient to drive expression of IL-10R1 in the colonic epithelium. Intestinal epithelial-specific IL-10R1-null mice were more susceptible to DSS (show PMP22 Antibodies) colitis associated with increased intestinal permeability.

  5. Inhibition of IL-10R signaling during bacillus Calmette-Guerin (BCG (show SLC11A1 Antibodies)) vaccination increases and balances IFN-gamma (show IFNG Antibodies) and IL-17A (show IL17A Antibodies) responses in favor of the host.

  6. IL-10R subunit-alpha signaling plays a key role in the development as well as B-cell help function of T (follicular helper) cells in vitro and in vivo.

  7. showed here that IL-17A (show IL17A Antibodies)-producing CD4 (show CD4 Antibodies)+ T cells expressed interleukin-10 receptor alpha (IL-10Ralpha) in vivo

  8. Data show that, in an IL-10 (show IL10 Antibodies)-dependent LPS (show TLR4 Antibodies) model of endotoxemia, dampening of the immune response requires expression of IL-10R1 in monocytes/macrophages and/or neutrophils but not in T cells nor B cells.

  9. reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor (show IL10RB Antibodies) antibody

  10. Immunocytochemistry data shows that the region of the adrenal gland responsible for the vast majority of corticosterone synthesis, the zona fasciculata, predominantly expresses the IL-10 (show IL10 Antibodies) receptor 1.

IL10RA Antigen Profile

Protein Summary

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Gene names and symbols associated with IL10RA

  • interleukin 10 receptor, alpha (IL10RA) antibody
  • interleukin 10 receptor, alpha (Il10ra) antibody
  • AW553859 antibody
  • CD210 antibody
  • CD210a antibody
  • CDw210 antibody
  • CDw210a antibody
  • HIL-10R antibody
  • IL-10R1 antibody
  • Il10r antibody
  • IL10R1 antibody
  • IL10RA antibody
  • mIL-10R antibody

Protein level used designations for IL10RA

interleukin 10 receptor 1 , interleukin-10 receptor subunit alpha , interleukin 10 receptor, alpha , interleukin-10 receptor subunit alpha-like , IL-10 receptor subunit alpha , IL-10R subunit 1 , IL-10R subunit alpha , IL-10RA , interleukin-10 receptor alpha chain , interleukin-10 receptor subunit 1 , IL-10R1

GENE ID SPECIES
419771 Gallus gallus
451580 Pan troglodytes
610823 Canis lupus familiaris
704383 Macaca mulatta
100396693 Callithrix jacchus
100436549 Pongo abelii
100469546 Ailuropoda melanoleuca
3587 Homo sapiens
16154 Mus musculus
100525654 Sus scrofa
513478 Bos taurus
117539 Rattus norvegicus
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