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The protein encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. Additionally we are shipping IL16 Antibodies (179) and IL16 Kits (63) and many more products for this protein.
Showing 10 out of 70 products:
Human IL16 Protein expressed in Escherichia coli (E. coli) - ABIN2667464
Center, Cruikshank, Zhang: Nuclear pro-IL-16 regulation of T cell proliferation: p27(KIP1)-dependent G0/G1 arrest mediated by inhibition of Skp2 transcription. in Journal of immunology (Baltimore, Md. : 1950) 2004
Show all 6 references for ABIN2667464
Human IL16 Protein expressed in Escherichia coli (E. coli) - ABIN667060
Bernstein, Plasterer, Schiff, Kitchen, Kitchen, Zack: CD4 expression on activated NK cells: ligation of CD4 induces cytokine expression and cell migration. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 2 references for ABIN667060
Human IL16 Protein expressed in Escherichia coli (E. coli) - ABIN2003630
Tsai, Tsai, Ho, Ho, Wu, Hung: Interleukin-12 and interleukin-16 in periodontal disease. in Cytokine 2005
We found that the rs1131445 T/C and rs4072111 T/C variants of IL-16 were significantly associated with increased risk of gastric cancer in Iranian population.
Data indicate that high interleukin-16 (IL-6 (show IL6 Proteins)), interferon-gamma (IFN-gamma (show IFNG Proteins)) and low interleukin-15 (IL-15 (show IL15 Proteins)) levels suggest active tuberculosis.
the results of our study suggested an association between the IL-16 rs4778889 polymorphism and an elevated risk of renal cell carcinoma (show MOK Proteins)
We observed highly significant reductions in the concentration of circulating interleukin (IL)-16, IL-7 (show IL7 Proteins), and Vascular Endothelial Growth Factor A (VEGF-A (show VEGFA Proteins)) in encephalomyelitis/chronic fatigue syndrome patients.
IL-16 rs1131445 C/T polymorphism is related to the susceptibility to cancer in Asians (meta-analysis)
The IL16 rs4072111 polymorphism may be associated with susceptibility to AD and the T allele may have a protective role in the progression of AD in an Iranian population.
intrathyroidal production of IL-14 (show TXLNA Proteins) and IL-16 associated with the pathogenesis of autoimmune thyroid disease
the lack of a relationship between genotype and serum levels of IL-16 seems to suggest a more complex regulation of this cytokine at the post-translational level and/or the interplay with other cytokines.
The results suggested that the variants in IL-16 gene rs11556218 site were associated with a decreased knee osteoarthritis risk after adjusting for age, sex, BMI, and smoking and drinking status.
Data suggest that thymic stromal lymphopoietin (TSLP (show TSLP Proteins)) and interleukin-16 (IL-16), expressed at early stages of disease, function to recruit malignant T cells to the skin.
The production of IL-16 contributed to lung damage as neutralization of IL-16 enhanced S. aureus clearance and resulted in diminished lung pathology in S. aureus pneumonia.
Data indicate that knockdown of translocator protein TSPO (show TSPO Proteins) by siRNAhad showed no effect on the productions of TNF-alpha (show TNF Proteins), IL-1beta (show IL1B Proteins) and IL-6 (show IL6 Proteins) in lipopolysaccharide (LPS (show TLR4 Proteins))-stimulated BV-2 microglia cells.
Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.
Data show overexpression of pro-IL-16 impaired resting B cell proliferation mediated through regulating nuclear factor (NF)-kappaB activation, and siRNA knock-down of pro-IL-16 expression decreased the level of p27(kip) and increased the level of Skp2.
We determined that ovalbumin (show OVA Proteins) (OVA)-sensitized mice have an increase in systemic tumor necrosis factor-alpha (show TNF Proteins) levels, and that serum or BAL fluid stimulation of bronchial epithelial cells results in production of IL-16
IL-16 induces a greater migratory response in the Th1 (show HAND1 Proteins) cell subset than in the Th2 subset.
interleukin-16 and its precursor have roles in T lymphocyte activation and growth [review]
IL-16 precursor mRNA and protein expression are dynamically regulated during CD4 (show CD4 Proteins)+ T cell activation by a calcineurin (show PPP3CA Proteins)-dependent mechanism; pro-IL-16 may influence T cell cycle regulation, although not in a dominant manner.
Caspase-3 (show CASP3 Proteins) mediated production of IL-16 by infiltrating CD4 (show CD4 Proteins)+ T cells, contributes to ongoing neuroinflammation by chemoattraction of additional waves of CD4 (show CD4 Proteins)+ T cells.
After femoral artery ligation, CD8 (show CD8A Proteins)+ T cells infiltrate the site of collateral vessel growth and recruit CD4 (show CD4 Proteins)+ mononuclear cells through the expression of IL-16
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
, interleukin 16 (lymphocyte chemoattractant factor)
, lymphocyte chemoattractant factor
, neuronal interleukin 16
, prointerleukin 16