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The protein encoded by IL17C is a T cell-derived cytokine that shares the sequence similarity with IL17. Additionally we are shipping IL17C Antibodies (84) and IL17C Kits (23) and many more products for this protein.
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IL-17C is an essential epithelial cell-derived cytokine.
Our study provides evidence that Staphylococcus aureus activates NOD2 in keratinocytes, resulting in an increased expression of IL-17C, a mechanism that may be dysregulated in atopic dermatitis.
Interleukin-17C is present in the tissue around aseptic loosened implants.
IL-17C is involved in the innate immune response of respiratory epithelial cells and is suppressed by cigarette smoke.
Data suggest that activation of TLR5 (show TLR5 Proteins) upregulates IL17C expression in cells from intestinal mucosa and colonic adenocarcinoma; IL17C expression is upregulated in intestinal mucosa cells from patients with ulcerative colitis compared with normal cells.
Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation.
In our pilot study, we discovered significant changes in methylation patterns of genes IL-7 (show IL7 Proteins), IL-13 (show IL13 Proteins), IL-17C and TYK2 (show TYK2 Proteins) between henodialysis patients and healthy subjects
IL-17C is an essential autocrine cytokine that regulates innate epithelial immune responses.
activation of NF-kappaB (show NFKB1 Proteins) (p65 (show GORASP1 Proteins)/p50 (show CD40 Proteins)) is crucial for the TNFalpha (show TNF Proteins)-induced stimulation of IL-17C expression in human keratinocytes
IL-17C and IL-17RE (show IL17RE Proteins) are dispensable for immunity to candidiasis
IL-17C plays a critical role in maintaining mucosal barrier integrity; IL-17C deficiency renders mice more susceptible to mucosal barrier breakage and development of colitis.
IL-17C-interleukin-17 receptor E (show IL17RE Proteins) induced the expression of a nuclear IkappaB family member, IkappaBzeta (show NFKBIZ Proteins), in Th17 cells to potentiate the Th17 cell response
Intranasal administration of adenovirus expressing IL-17 (show IL17A Proteins) results in bronchoalveolar lavage neutrophilia and Th1 (show HAND1 Proteins)-type inflammatory gene expression in the lung.
IL-17B (show IL17B Proteins) and IL-17C play an important role in the pathogenesis of inflammatory arthritis.
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells.
, Interleukin 17-3
, cytokine CX2