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The protein encoded by IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. Additionally we are shipping IL18RAP Proteins (24) and IL18RAP Kits (7) and many more products for this protein.
Showing 10 out of 87 products:
Human Monoclonal IL18RAP Primary Antibody for FACS - ABIN4895459
Spallanzani, Torres, Avila, Ziblat, Iraolagoitia, Rossi, Domaica, Fuertes, Rabinovich, Zwirner: Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors. in Journal of immunology (Baltimore, Md. : 1950) 2015
Show all 3 references for ABIN4895459
Human Monoclonal IL18RAP Primary Antibody for ELISA, WB - ABIN522252
Koskinen, Einarsdottir, Dukes, Heap, Dubois, Korponay-Szabo, Kaukinen, Kurppa, Ziberna, Vatta, Not, Ventura, Sistonen, Adány, Pocsai, Széles, Mäki, Kere, Wijmenga, van Heel, Saavalainen: Association study of the IL18RAP locus in three European populations with coeliac disease. in Human molecular genetics 2009
Show all 2 references for ABIN522252
Human Polyclonal IL18RAP Primary Antibody for WB - ABIN2775270
Fukushima, Ikehara, Yamashita: Functional role played by the glycosylphosphatidylinositol anchor glycan of CD48 in interleukin-18-induced interferon-gamma production. in The Journal of biological chemistry 2005
Human Polyclonal IL18RAP Primary Antibody for IF (p), IHC (p) - ABIN748058
Valente, Yoshida, Izadpanah, Delafontaine, Siebenlist, Chandrasekar: Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin. in Cellular signalling 2013
Human Monoclonal IL18RAP Primary Antibody for FACS, WB - ABIN4899083
Takei, Hoshino, Matsunaga, Sakazaki, Sawada, Oda, Takenaka, Imaoka, Kinoshita, Honda, Ida, Fukuda, Aizawa: Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis. in Arthritis research & therapy 2011
Human Polyclonal IL18RAP Primary Antibody for EIA, WB - ABIN453701
Debets, Timans, Churakowa, Zurawski, de Waal Malefyt, Moore, Abrams, OGarra, Bazan, Kastelein: IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18. in Journal of immunology (Baltimore, Md. : 1950) 2000
These findings suggested that IL-18RAP rs917997, IL-32 (show IL32 Antibodies) rs2015620, IL-22 (show IL22 Antibodies) rs1179251, and interactions between these polymorphisms and H. pylori infection were associated with risks of gastric lesions
some SNPs of ST2-IL18R1-IL18RAP gene cluster might increase the risk of susceptibility of Graves' disease (GD) and Hashimoto's thyroiditis (HT) in Chinese Han population.
This meta-analysis provides robust estimates that IL18RAP rs917997 and chemokine (C-C motif) receptor 3 (show CCR3 Antibodies) rs6441961 are potential risk factors for celiac disease in European populations.
results demonstrate clear functional consequences of the rs917997 risk polymorphism; this polymorphism leads to a loss-of-function through decreased IL-18RAP, IL-18R1 (show IL18R1 Antibodies), and IL-1R1 protein expression, which impairs autocrine IL-18 (show IL18 Antibodies) and IL-1 (show IL1A Antibodies) signaling
The SNP modified IL18RAP surface protein expression by NK cells.
Data indicate that MyD88 (show MYD88 Antibodies) works together with the IL-1 (show IL1A Antibodies)/IL-18 (show IL18 Antibodies) receptors, can interact with two distinct sorting adaptors, TRAM (show TRAM1 Antibodies) and Mal (show MAL Antibodies), in a conserved manner.
Data suggest that IL-18RAP and IL-18R1 (show IL18R1 Antibodies) single-nucleotide polymorphisms identify African-American infants at risk for bronchopulmonary dysplasia.
IL-18 (show IL18 Antibodies), IL-18 receptor alpha (show IL18R1 Antibodies), and CD48 (show CD48 Antibodies) complex formation via glycosylphosphatidylinositol anchor glycan triggers binding to IL-18 receptor beta, and thereby induces intracellular signal transduction and IFN-gamma (show IFNG Antibodies) production.
Truncated forms of IL-18RAP may be involved in the complex mechanism of IL-18 (show IL18 Antibodies) activity regulation.
Variations in IL18RAP is associated with celiac disease
Our data highlight the considerable complexity of the IL-18 (show IL18 Antibodies) regulation activity in the mouse brain and further support an important central role for IL-18 (show IL18 Antibodies).
This study demonstrates that IL-18 (show IL18 Antibodies) signals are abolished in accessory protein-like (AcPL)-deficient mice and cells, and suggests that AcPL is a critical and specific cell surface receptor required for IL-18 (show IL18 Antibodies) signaling.
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
interleukin 18 receptor accessory protein
, IL-18 receptor beta
, interleukin-18 receptor accessory protein-like
, CD218 antigen-like family member B
, IL-18 receptor accessory protein
, interleukin-1 receptor 7
, interleukin-18 receptor accessory protein
, interleukin-18 receptor beta
, AcPL accessory protein-like)