Interleukin 22 Proteins (IL22)

The protein encoded by IL22 is a cytokine that shares the sequence similarity with IL17. Additionally we are shipping Interleukin 22 Antibodies (293) and Interleukin 22 Kits (76) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL22 53342 Q8TAD2
IL22 50929 Q9JJY9
Rat IL22 IL22 500836  
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Top Interleukin 22 Proteins at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 10 μg Log in to see 20 to 21 Days
$173.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$211.97
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$211.97
Details
HOST_HEK-293 Cells Human Un-conjugated 10 μg Log in to see 2 to 3 Days
$325.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$233.72
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$720.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 10 μg Log in to see 3 to 4 Days
$85.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   4 pack Log in to see 10 to 12 Days
$86.96
Details

IL22 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , , ,
Mouse (Murine) ,
, ,

Top referenced Interleukin 22 Proteins

  1. Human IL22 Protein expressed in Escherichia coli (E. coli) - ABIN2667507 : Chung, Yang, Chang, Ma, Tian, Dong: Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes. in Cell research 2006 (PubMed)
    Show all 9 references for 2667507

  2. Human IL22 Protein expressed in Escherichia coli (E. coli) - ABIN2667506 : Dumoutier, Louahed, Renauld: Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 7 references for 2667506

  3. Mouse (Murine) IL22 Protein expressed in Escherichia coli (E. coli) - ABIN2667509 : Kotenko, Izotova, Mirochnitchenko, Esterova, Dickensheets, Donnelly, Pestka: Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 4 references for 2667509

  4. Mouse (Murine) IL22 Protein expressed in Escherichia coli (E. coli) - ABIN2667512 : Xie, Aggarwal, Ho, Foster, Zhang, Stinson, Wood, Goddard, Gurney: Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. in The Journal of biological chemistry 2000 (PubMed)
    Show all 4 references for 2667512

  5. Human IL22 Protein expressed in Escherichia coli (E. coli) - ABIN2005393 : Pestka, Krause, Sarkar, Walter, Shi, Fisher: Interleukin-10 and related cytokines and receptors. in Annual review of immunology 2004 (PubMed)

More Proteins for Interleukin 22 (IL22) Interaction Partners

Zebrafish Interleukin 22 (IL22) interaction partners

  1. Expression analysis of IL-22, IL-26 (show IL26 Proteins) and two IFN-gamma (show IFNG Proteins) genes suggests an active role of these genes in immune responses in fish.

Human Interleukin 22 (IL22) interaction partners

  1. Study of the expression of IL-17 (show IL17A Proteins) provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor.

  2. IL-23 (show IL23A Proteins) released by keratinocytes in response to endogenous TLR4 (show TLR4 Proteins) ligands causes skin DCs, which selectively express IL-23R (show IL23R Proteins), to up-regulate their endogenous IL-23 (show IL23A Proteins) production and drive an IL-22 response in naive CD4 (show CD4 Proteins)(+) T cells that mediates epidermal thickening.

  3. patients with T2DM and CAD exhibit increased serum IL-22 levels. Elevated serum IL-22 is associated with the incidence of CAD and T2DM. However, further in vitro study established the protective role of IL-22 against endothelial dysfunction, an essential process involved in the early development of atherosclerosis and vascular complications in T2DM. IL-22 might exert different functions under different context.

  4. plasma levels highly elevated after major liver resection

  5. IL-22 and its receptor have a crucial role in the development and pathogenesis of uveitis by facilitating inflammatory cell infiltration.

  6. there was no association between IL-22 SNPs (rs2227485, rs2272478, rs2227491) and the development of ulcerative colitis in a Mexican population

  7. The mutual benefit gained from interactions between the host and commensal intestinal bacteria-derived factors is an expanding field of research beginning to affect clinical practice. Data presented herein propose a supportive and fine-tuning role for butyrate in IL-22 signaling that might be therapeutically exploited by local butyrate administration

  8. this paper shows that human gammadelta T cell-antigen-presenting cells stimulate CD4 (show CD4 Proteins)+ T cell responses distinct from those induced by myeloid antigen-presenting cells to promote local barrier defense via mucosal release of IL-22 and calprotectin (show S100A8 Proteins)

  9. There was a significant direct correlation between levels of IL-10 (show IL10 Proteins) and IL-22 in patients group (p=0.0005). The clinical severity of psoriasis was significantly correlated with high levels of IL-22 (p<0.0001).

  10. The levels of IL-22 mRNA in middle ear effusion of otitis media with effusion patients was higher in those with sinusitis than without. IL-22 expression was significantly higher in mucoid and purulent middle ear fluid samples than in serous fluid samples.

Mouse (Murine) Interleukin 22 (IL22) interaction partners

  1. our data suggest that IL-20 (show IL20 Proteins) subfamily cytokines, particularly IL-20 (show IL20 Proteins), IL-22, and IL-24 (show IL24 Proteins), might provide therapeutic benefit for patients with Diabetic foot ulcers (DFU) .

  2. IL-23 (show IL23A Proteins) released by keratinocytes in response to endogenous TLR4 (show TLR4 Proteins) ligands causes skin DCs, which selectively express IL-23R (show IL23R Proteins), to up-regulate their endogenous IL-23 (show IL23A Proteins) production and drive an IL-22 response in naive CD4 (show CD4 Proteins)(+) T cells that mediates epidermal thickening.

  3. innate immune cell-derived IL-22 is required for efficient liver regeneration and secretion of IL-22 in the regenerating liver is modulated by the ATP receptor (show P2RX4 Proteins), P2X1 (show P2RX1 Proteins)

  4. IL-22 and its receptor have a crucial role in the development and pathogenesis of uveitis by facilitating inflammatory cell infiltration.

  5. These results demonstrate a central role for the AIM2 (show AIM2 Proteins) inflammasome in preventing dysbiosis and intestinal inflammation through regulation of the IL-18 (show IL18 Proteins)/IL-22BP (show IL22RA2 Proteins)/IL-22 and STAT3 (show STAT3 Proteins) pathway

  6. We therefore postulate IL-22 as an important enhancer of the GC reaction, maintaining chemokine (show CCL1 Proteins) levels for the persistence of GC reactions, essential for the production of autoantibody-secreting plasma cells. Blocking IL-22 might therefore prevent immune-complex deposition and destruction of joints in RA patients.

  7. AhR (show AHR Proteins) has a direct role in IL-22 production by Th17 cells in the mouse ear skin, but not by gammadelta T cells, CD4 (show CD4 Proteins)(-) CD8 (show CD8A Proteins)(-) TCRbeta(+) T cells and ILCs.

  8. Taken together, our results demonstrate that Dok-1 (show DOK1 Proteins) and Dok-2 negatively regulate intestinal inflammation, apparently through the induction of IL-17A (show IL17A Proteins) and IL-22 expression.

  9. Upregulation of IL-22 in combination with a complete loss of its negative regulator IL-22BP (show IL22RA2 Proteins), and increased downstream STAT3 (show STAT3 Proteins)-signaling in K8(-/-) and K8(-/-)Apc (show APC Proteins)(Min/+) colonic epithelia confirmed that the IL-22 pathway, important in inflammation, proliferation and tissue regeneration

  10. this study shows that serum IL-22/IL-22BP (show IL22RA2 Proteins) protein ratio strongly correlates with psoriasis severity

Cow (Bovine) Interleukin 22 (IL22) interaction partners

  1. SNPs in IFNG (show IFNG Proteins), IFNGR1 (show IFNGR1 Proteins) and R2, IL22, and IL22RA1 (show IL22RA1 Proteins) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.

  2. Study concludes that bovine gamma/delta T cells are important sources of IL-22 and suggest a role for this cytokine in regulating immune responses at mucosal surfaces, including the gut (show GUSB Proteins).

Interleukin 22 (IL22) Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.

Gene names and symbols associated with Interleukin 22 Proteins (IL22)

  • interleukin 22 (il22)
  • interleukin 17D (IL17D)
  • interleukin 22 (IL22)
  • interleukin 22 (Il22)
  • interleukin 22 (LOC100348980)
  • interleukin 22 (IL-22)
  • IL-17D protein
  • IL-21 protein
  • IL-22 protein
  • IL-22a protein
  • IL-27 protein
  • IL-D110 protein
  • IL-TIF protein
  • IL27 protein
  • Iltif protein
  • ILTIFa protein
  • interleukin-22 protein
  • RGD1561292 protein
  • TIFa protein
  • TIFIL-23 protein
  • zcyto18 protein

Protein level used designations for Interleukin 22 Proteins (IL22)

IL-24 , Ifnphi6 , interleukin 27 , interleukin-17D , interleukin-27 , IL-10-related T-cell-derived inducible factor , IL-10-related T-cell-derived-inducible factor , cytokine Zcyto18 , interleukin-22 , IL-TIF alpha , ILTIF alpha , interleukin 10-related T cell-derived inducible factor , interleukin-22a

GENE ID SPECIES
553964 Danio rerio
53342 Homo sapiens
50616 Homo sapiens
50929 Mus musculus
481153 Canis lupus familiaris
507778 Bos taurus
500836 Rattus norvegicus
100348980 Oryctolagus cuniculus
595104 Sus scrofa
100860910 Capra hircus
417838 Gallus gallus
100885770 Ovis aries
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