Interleukin 27 Proteins (IL27)

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Antibodies (165) and IL27 Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL27 53342 Q8TAD2
IL27 246779 Q8K3I6
IL27 365368  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top IL27 Proteins at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_CHO Cells Human His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$784.00
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$800.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   1 mg Log in to see 2 to 3 Days
$5,200.00
Details
HOST_HEK293 Human Un-conjugated   10 μg Log in to see 2 to 3 Days
$583.21
Details
HOST_HEK-293 Cells Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$460.00
Details

IL27 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Mouse (Murine) , ,

Rat (Rattus)

Top referenced IL27 Proteins

  1. Human IL27 Protein expressed in Wheat germ - ABIN1307800 : Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Show all 2 Pubmed References

More Proteins for Interleukin 27 (IL27) Interaction Partners

Human Interleukin 27 (IL27) interaction partners

  1. HIV and Tat (show TAT Proteins) inhibit LPS (show IRF6 Proteins)-induced IL-27 production in human macrophages via distinct mechanisms: Tat (show TAT Proteins) through the inhibition of cIAP-1 (show BIRC2 Proteins)-TRAF-6 (show TRAF6 Proteins) and subsequent inhibition of PI3K (show PIK3CA Proteins) and p38 (show CRK Proteins) MAPKs, whereas HIV through the inhibition of p38 MAPK (show MAPK14 Proteins) activation.

  2. IL27 (show EBI3 Proteins) recapitulates IFN-gamma (show IFNG Proteins) responses in hepatocellular carcinoma cells, but is inhibited by IL6 (show IL6 Proteins)-type cytokines.

  3. These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (show IL1B Proteins) secretion levels triggered by dual LPS (show IRF6 Proteins)-ATP stimulation.

  4. IL-27 enhanced the cytotoxicity and suppressed the proliferation of ovarian cancer cells

  5. Study of the expression of IL-17 (show IL17A Proteins) provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor.

  6. the sIL (show PMEL Proteins)-6R/p28 (show PSMD10 Proteins) fusion protein (FP) upregulated IFN-lambda1 expression by increasing the binding abilities of c-Fos and activating transcription factor 1 (show AFT1 Proteins) to the IFN-lambda1 promoter via the p38 MAPK (show MAPK14 Proteins) signaling pathway; results demonstrate the important role of sIL (show PMEL Proteins)-6R/p28 (show PSMD10 Proteins) FP in mediating virus-induced type III IFN production.

  7. These results identify IL-27 and its specific receptor IL27RA (show IL27RA Proteins) as a critical immune axis for the antiviral immune response and as robust correlates of viral load and proviral reservoir size in mononuclear leukocytes in HIV infection.

  8. serum IL-27 levels were significantly higher in stage III EV71-infected hand, foot, and mouth disease patients with early cardiopulmonary failure and strong correlation with CRP (show CRP Proteins) levels; IL27p28 polymorphisms (rs153109, rs17855750, and rs181206) did not influence IL-27 production, and these three SNPs were not associated with EV71 infection risk and clinical stage

  9. these results suggest that IL-27 might predominantly play a protective role in the pathogenesis of psoriasis through abrogating Th17 differentiation.

  10. our data suggest a previously unrecognized role for IL-27 in regulating epithelial cell proliferation and antiviral host defense during the normal wound healing response.

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. results identified a novel mechanism of action of IL-27 on Tregs in the context of cancers.

  2. These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (show IL1B Proteins) secretion levels triggered by dual LPS (show TLR4 Proteins)-ATP stimulation.

  3. findings show that PGE2 inhibits IL-27 production in macrophages and in splenic conventional dendritic cells; and identify a novel pathway consisting of signaling through EP2/EP4-->induction of cAMP-->downregulation of IFN regulatory factor 1 expression and binding to the p28 IFN-stimulated response element site

  4. these data provide the first evidence that IL-27 signals directly to B (show TDO2 Proteins) cells promote GCs (show UGCG Proteins) and support the role of IL-27 in lupus.

  5. this study shows that IL-27 plays an important role in immune response and pathogen clearance during infection with Candida parapsilosis

  6. Inhibition of IL-27p28 also enhanced the suppressive capacity of adoptively transferred CD4 (show CD4 Proteins)(+) nTregs by increasing the stability of Foxp3 (show FOXP3 Proteins) expression.

  7. These data provide evidence of a central role of IL-27 for the control of Th2-mediated allergic diseases.

  8. These data indicate that endogenous IL-27 limits pathology during parainfluenza virus infection

  9. our data suggest a previously unrecognized role for IL-27 in regulating epithelial cell proliferation and antiviral host defense during the normal wound healing response.

  10. recombinant IL-30 showed its biological activity by inhibiting Th17 differentiating from naive CD4 (show CD4 Proteins)(+) T cells. Therefore, this method of express and purifying IL-30 provides novel procedures to facilitate structural and functions studies of IL-30.

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 Protein Profile

Protein Summary

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with Interleukin 27 Proteins (IL27)

  • interleukin 27 (IL27)
  • interleukin 17D (IL17D)
  • interleukin 27 (Il27)
  • interleukin 27-like (LOC100349321)
  • IL-17D protein
  • IL-22 protein
  • IL-27 protein
  • IL-27A protein
  • IL-27p28 protein
  • IL27 protein
  • IL27A protein
  • IL27p28 protein
  • Il30 protein
  • p28 protein
  • RGD1561420 protein

Protein level used designations for Interleukin 27 Proteins (IL27)

interleukin 27 , interleukin-17D , interleukin-27 , IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interleukin 27 p28 subunit , p28 , interluekin 27

GENE ID SPECIES
737725 Pan troglodytes
53342 Homo sapiens
246778 Homo sapiens
246779 Mus musculus
365368 Rattus norvegicus
100724612 Cavia porcellus
493187 Sus scrofa
607880 Canis lupus familiaris
614927 Bos taurus
101122495 Ovis aries
101093822 Felis catus
100349321 Oryctolagus cuniculus
Selected quality suppliers for IL27 Proteins (IL27)
Did you look for something else?