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Interleukin 27 Receptor, alpha (IL27RA) ELISA Kits

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Additionally we are shipping IL27 Receptor alpha Antibodies (89) and IL27 Receptor alpha Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
IL27RA 9466 Q6UWB1
IL27RA 50931 O70394
Anti-Rat IL27RA IL27RA 288905  
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Top IL27 Receptor alpha ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.039 ng/ml 0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 19.53 pg/ml 5000-78.13 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for IL27 Receptor alpha Interaction Partners

Human Interleukin 27 Receptor, alpha (IL27RA) interaction partners

  1. The significant expression of IL-27 (show IL27 ELISA Kits) in TB and the negative influence of IL-27R on T cell function demonstrate the pathway by which this cytokine/receptor (show EBI3 ELISA Kits) pair is detrimental in TB.

  2. natural sIL (show PMEL ELISA Kits)-27Ralpha binds rIL (show PDLIM4 ELISA Kits)-27, inhibits IL-27 (show IL27 ELISA Kits) binding to its cell surface receptor, and is a potent inhibitor of IL-27 (show IL27 ELISA Kits) signaling, as shown by its ability to specifically block IL-27 (show IL27 ELISA Kits)-mediated STAT (show STAT1 ELISA Kits) activation, at low molar excess over IL-27 (show IL27 ELISA Kits).

  3. Aberrant hypermethylation and reduced expression of IL27RA is associated with myelodysplastic syndromes.

  4. TCCR/WSX-1 is closely associated with angiogenesis and could serve as a novel therapeutic target in patients with age-related macular degeneration.

  5. Mutations in the transmembrane and juxtamembrane domains enhance IL27R transforming activity.

  6. WSX-1 is essential for transcriptional activation of STAT1 (show STAT1 ELISA Kits) and for augmenting the induction of T-bet expression during initiation of Th1 (show TH1L ELISA Kits) cell differentiation.

  7. WSX-1 together with the cytokine receptor (show EBI3 ELISA Kits) gp130 (show IL6ST ELISA Kits) constitutes a functional signal-transducing receptor for IL-27 (show IL27 ELISA Kits).

  8. IL-27R possesses hematopoietic cell-transforming properties

  9. These results indicate that humanin protects neurons by binding to a complex or complexes involving CNTFR (show CNTFR ELISA Kits)/WSX-1/gp130 (show IL6ST ELISA Kits).

  10. Results reveal an interleukin 27 (show IL27 ELISA Kits)-independent function of WSX1 sensitizing natural killer cell-mediated antitumor surveillance.

Mouse (Murine) Interleukin 27 Receptor, alpha (IL27RA) interaction partners

  1. The combination of mutant p53 (show TP53 ELISA Kits) & IL27RA(-/-) causes spontaneous liver inflammation, steatosis, and fibrosis, whereas either gene alone has no effects on the liver.

  2. IL-10 (show IL10 ELISA Kits) production by CD4 (show CD4 ELISA Kits)(+) YFP(+) T cells is controlled systemically during malaria infection through IL-27 (show IL27 ELISA Kits) receptor signaling that is supported after CD4 (show CD4 ELISA Kits)(+) T cell priming by ICOS (show ICOS ELISA Kits) signaling.

  3. The significant expression of IL-27 (show IL27 ELISA Kits) in TB and the negative influence of IL-27R on T cell function demonstrate the pathway by which this cytokine/receptor (show LEPR ELISA Kits) pair is detrimental in TB.

  4. IL-27R-mediated regulation of IL-17 (show IL17A ELISA Kits) controls the development of respiratory syncytial virus-associated pathogenesis.

  5. CCL4 (show CCL4 ELISA Kits) and CCL5 (show CCL5 ELISA Kits) expression was higher in livers of infected WSX-1(-/-) mice than infected WT mice, and hepatic CD4 (show CD4 ELISA Kits) T cells from WSX-1(-/-) mice expressed higher levels of CCR5 (show CCR5 ELISA Kits) than cells from WT mice

  6. The loss of IL-27R signaling across the whole mouse resulted in reduced viral control and a slight increase in the number of virus-specific CD4 (show CD4 ELISA Kits) T cells at early stages of viral infection.

  7. Diminution of the Th1 (show HAND1 ELISA Kits) response in infected Il27ra mice in vivo by neutralization of IL-12p40 attenuated CCR5 (show CCR5 ELISA Kits) expression.

  8. These findings establish a novel antiatherogenic role for IL-27 (show IL27 ELISA Kits) receptor signaling, which acts to suppress the production of proinflammatory cytokines and chemokines and to curb the recruitment of inflammatory myeloid cells into atherosclerotic aortas.

  9. In Th1 (show HAND1 ELISA Kits)-dependent autoinflammatory lesions, IL-27Ralpha has a biphasic role in vivo, initially pathogenic, but ultimately playing a protective role by regulating immune responses and attenuating disease.

  10. Data show that the deletion of Il27ra ameliorates pathology in the pristane-induced SLE model.

IL27 Receptor alpha (IL27RA) Antigen Profile

Antigen Summary

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.

Gene names and symbols associated with IL27RA

  • interleukin 27 receptor, alpha (IL27RA) antibody
  • interleukin 27 receptor, alpha (Il27ra) antibody
  • CRL1 antibody
  • IL-27R antibody
  • IL-27RA antibody
  • IL27R antibody
  • IL27RA antibody
  • Tccr antibody
  • WSX-1 antibody
  • Wsx1 antibody
  • zcytor1 antibody

Protein level used designations for IL27RA

interleukin 27 receptor, alpha , class I cytokine receptor , interleukin-27 receptor subunit alpha , type-I T cell cytokine receptor , IL-27 receptor subunit alpha , IL-27R subunit alpha , IL-27R-alpha , T-cell cytokine receptor type 1 , cytokine receptor WSX-1 , cytokine receptor-like 1 , type I T-cell cytokine receptor , IL-27RA , T cell cytokine receptor , T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1 , cytokine receptor family, class 1 (WSXWS), member 1

GENE ID SPECIES
456370 Pan troglodytes
484907 Canis lupus familiaris
514529 Bos taurus
717549 Macaca mulatta
9466 Homo sapiens
50931 Mus musculus
288905 Rattus norvegicus
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