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Interleukin 28A (Interferon, lambda 2) Proteins (IL28A)

Cytokine with immunomodulatory activity. Additionally we are shipping Interleukin 28A (Interferon, lambda 2) Antibodies (74) and Interleukin 28A (Interferon, lambda 2) Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL28A 330496 Q4VK74
IL28A 282616 Q8IZJ0
IL28A    
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Top Interleukin 28A (Interferon, lambda 2) Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$1,265.25
Details
HOST_Human Cells Mouse His tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 15 to 19 Days
$314.16
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   20 μg Log in to see 15 to 19 Days
$314.16
Details

IL28A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , ,
,
General

More Proteins for Interleukin 28A (Interferon, lambda 2) (IL28A) Interaction Partners

Mouse (Murine) Interleukin 28A (Interferon, lambda 2) (IL28A) interaction partners

  1. IL-28A is capable of exacerbating a T-cell-mediated autoimmune disease.

  2. Data indicate that rotavirus infection induces production of interferon (show IFNA Proteins)-lambda (IFN-lambda) and interleukin 22 (IL-22 (show IL22 Proteins)) by intestinal epithelial cells.

  3. IL-28A exerts its antiinflammatory effect by restricting recruitment of IL-1b (show IL1B Proteins)-expressing neutrophils

  4. The level of IFN-lambda2 was significantly increased in the infected cells treated with with shRNAs against influenza a virus M1.

  5. IFN-lambda2 limits VSV replication in the mouse lung.

  6. Data indicate that IPS-1 (show ISYNA1 Proteins)-dependent pathway plays a crucial role in type III IFN production by CD8 (show CD8A Proteins)(+) dendritic cells (DCs) and hepatocytes in response to hepatitis C virus (HCV), leading to cytoplasmic antiviral protein expressions.

Human Interleukin 28A (Interferon, lambda 2) (IL28A) interaction partners

  1. NS of severe fever with thrombocytopenia syndrome virus inhibited the activity of IFN-alpha1 (show IFNA1 Proteins), IFN-beta (show IFNB1 Proteins), IFN-lambda1 and IFN-lambda2 through inhibition of STAT1 (show STAT1 Proteins) phosphorylation.

  2. Studies indicate that the type III interferons (IFNs) or IFN-lambdas consists of four members: IFN-lambda1 (IL-29 (show IL29 Proteins)), IFN-lambda2 (IL28A), IFN-lambda3 (IL-28B (show IL28B Proteins)) and IFN-lambda4.

  3. Results showed no association between genotypes and alleles of IL28A, IL28B (show IL28B Proteins) or IL29 (show IL29 Proteins) polymorphisms and Hepatitis C virus infection.

  4. this study provides evidence for potential IL-28A participation in Behcet's diseaseand its value as a therapeutic agent.

  5. Interferon (show IFNA Proteins) regulatory factor (IRF)-3 (show IRF3 Proteins) and -7 are the key transcriptional factors for the induction of IL-28A and IL-28B (show IL28B Proteins) genes, whereas NF-kappaB (show NFKB1 Proteins) is an additional requirement for the induction of the IL-29 (show IL29 Proteins) gene.

  6. The results show that IL-28A/IL-28AR1 dyad-induced wound healing migration requires NF-kappaB (show NFKB1 Proteins)-mediated MMP-9 (show MMP9 Proteins) expression by MAPK (show MAPK1 Proteins) activation.

  7. IL-28 genotype was not associated with response to interferon (show IFNA Proteins) treatment (OR for GT/GG vs. TT, 0.881 (95%CI 0.388 - 2.002); P = 0.762; OR for CT/CC vs. TT, 0.902 (95%CI 0.458 - 1.778); P = 0.766).

  8. p38 MAPK (show MAPK14 Proteins) pathway mediates IL-28A-induced cell migration through MMP-9 (show MMP9 Proteins) expression by activating NF-kappaB (show NFKB1 Proteins) and AP-1 (show FOSB Proteins) binding motifs.

  9. Elevated expression of inflammatory cytokines (IL-5 (show IL5 Proteins), IL-20 (show IL20 Proteins), and IL-28A) is associated with bladder cancer development.

  10. Plasmacytoid dendritic cells are major producers of IFN-lambda2 (a type III interferon (show IFNA Proteins)) in response to viral stimulation.

Interleukin 28A (Interferon, lambda 2) (IL28A) Protein Profile

Protein Summary

Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Gene names and symbols associated with IL28A

  • interferon lambda 2 (Ifnl2)
  • interferon, lambda 2 (IFNL2)
  • EG330496 protein
  • IL-28A protein
  • IL28A protein

Protein level used designations for IL28A

IFN-lambda-2 , IFN-lambda2 , interferon lambda-2 , interferon-lambda2 , interleukin 28A , interleukin-28A , cytokine Zcyto20 , interferon lambda 2 , interferon-lambda 2 , interleukin 28A (interferon, lambda 2)

GENE ID SPECIES
330496 Mus musculus
282616 Homo sapiens
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