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IL28A encodes a cytokine distantly related to type I interferons and the IL-10 family. Additionally we are shipping Interleukin 28A (Interferon, lambda 2) Antibodies (81) and Interleukin 28A (Interferon, lambda 2) Proteins (22) and many more products for this protein.
Showing 4 out of 31 products:
Human IL28A ELISA Kit for Sandwich ELISA - ABIN365217
Shaker, Sadik: Polymorphisms in interleukin-10 and interleukin-28B genes in Egyptian patients with chronic hepatitis C virus genotype 4 and their effect on the response to pegylated interferon/ribavirin-therapy. in Journal of gastroenterology and hepatology 2012
Mouse (Murine) IL28A ELISA Kit for Sandwich ELISA - ABIN625145
Cui, Clark, Liu, Xu, Guo, Hu: Viral DNA-Dependent Induction of Innate Immune Response to Hepatitis B Virus in Immortalized Mouse Hepatocytes. in Journal of virology 2015
IL28 controls proliferation of IECs in mice with colitis and accelerates mucosal healing by activating STAT1 (show STAT1 ELISA Kits).
IL-28A is capable of exacerbating a T-cell-mediated autoimmune disease.
Data indicate that rotavirus infection induces production of interferon (show IFNA ELISA Kits)-lambda (IFN-lambda) and interleukin 22 (IL-22 (show IL22 ELISA Kits)) by intestinal epithelial cells.
IL-28A exerts its antiinflammatory effect by restricting recruitment of IL-1b (show IL1B ELISA Kits)-expressing neutrophils
The level of IFN-lambda2 was significantly increased in the infected cells treated with with shRNAs against influenza a virus M1.
IFN-lambda2 limits VSV replication in the mouse lung.
Data indicate that IPS-1 (show ISYNA1 ELISA Kits)-dependent pathway plays a crucial role in type III IFN production by CD8 (show CD8A ELISA Kits)(+) dendritic cells (DCs) and hepatocytes in response to hepatitis C virus (HCV), leading to cytoplasmic antiviral protein expressions.
NS of severe fever with thrombocytopenia syndrome virus inhibited the activity of IFN-alpha1 (show IFNA1 ELISA Kits), IFN-beta (show IFNB1 ELISA Kits), IFN-lambda1 and IFN-lambda2 through inhibition of STAT1 (show STAT1 ELISA Kits) phosphorylation.
Studies indicate that the type III interferons (IFNs) or IFN-lambdas consists of four members: IFN-lambda1 (IL-29 (show IL29 ELISA Kits)), IFN-lambda2 (IL28A), IFN-lambda3 (IL-28B (show IL28B ELISA Kits)) and IFN-lambda4.
Results showed no association between genotypes and alleles of IL28A, IL28B (show IL28B ELISA Kits) or IL29 (show IL29 ELISA Kits) polymorphisms and Hepatitis C virus infection.
this study provides evidence for potential IL-28A participation in Behcet's diseaseand its value as a therapeutic agent.
Interferon (show IFNA ELISA Kits) regulatory factor (IRF)-3 (show IRF3 ELISA Kits) and -7 are the key transcriptional factors for the induction of IL-28A and IL-28B (show IL28B ELISA Kits) genes, whereas NF-kappaB (show NFKB1 ELISA Kits) is an additional requirement for the induction of the IL-29 (show IL29 ELISA Kits) gene.
The results show that IL-28A/IL-28AR1 dyad-induced wound healing migration requires NF-kappaB (show NFKB1 ELISA Kits)-mediated MMP-9 (show MMP9 ELISA Kits) expression by MAPK (show MAPK1 ELISA Kits) activation.
IL-28 genotype was not associated with response to interferon (show IFNA ELISA Kits) treatment (OR for GT/GG vs. TT, 0.881 (95%CI 0.388 - 2.002); P = 0.762; OR for CT/CC vs. TT, 0.902 (95%CI 0.458 - 1.778); P = 0.766).
p38 MAPK (show MAPK14 ELISA Kits) pathway mediates IL-28A-induced cell migration through MMP-9 (show MMP9 ELISA Kits) expression by activating NF-kappaB (show NFKB1 ELISA Kits) and AP-1 (show FOSB ELISA Kits) binding motifs.
Elevated expression of inflammatory cytokines (IL-5 (show IL5 ELISA Kits), IL-20 (show IL20 ELISA Kits), and IL-28A) is associated with bladder cancer development.
Plasmacytoid dendritic cells are major producers of IFN-lambda2 (a type III interferon (show IFNA ELISA Kits)) in response to viral stimulation.
Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
, interferon lambda-2
, interleukin 28A
, cytokine Zcyto20
, interferon lambda 2
, interferon-lambda 2
, interleukin 28A (interferon, lambda 2)