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Interleukin 31 Proteins (IL31)

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. Additionally we are shipping Interleukin 31 Antibodies (116) and Interleukin 31 Kits (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL31 386653 Q6EBC2
IL31 76399 Q6EAL8
IL31 690028  
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Top Interleukin 31 Proteins at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 100 μg Log in to see 4 to 6 Days
$638.00
Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$173.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 5 Days
$522.50
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$841.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 2 to 3 Days
$861.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 11 Days
$300.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 7 to 9 Days
$328.21
Details

IL31 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine) , ,
,
Rat (Rattus)

More Proteins for Interleukin 31 (IL31) Interaction Partners

Human Interleukin 31 (IL31) interaction partners

  1. While serum TSLP (show TSLP Proteins) levels were unaffected by concomitant allergies and atopic comorbidities, serum levels of IL-31, IL-33 (show IL33 Proteins) and sST2 (show SSTR2 Proteins) were affected to a small extent. We found a positive correlation between TSLP (show TSLP Proteins), IL-31 and IL-33 (show IL33 Proteins), and an inverse relationship between IL-33 (show IL33 Proteins) and sST2 (show SSTR2 Proteins)

  2. Suggest that IL-31 gene may play a role in the development of systemic lupus erythematosus.

  3. High IL31 expression is associated with Endometrial Cancer.

  4. In a CML (show BCR Proteins) patient with pruritus receiving imatinib mesylate, IL-31 and IL-33 (show IL33 Proteins) serum levels were significantly higher than controls. Imatinib could cause keratinocyte injury, the release of IL-33 (show IL33 Proteins), and the consequent interaction with its receptor on mast cells, inducing IL-31 secretion. The IL-31/IL-33 (show IL33 Proteins) axis may be involved in the pathogenesis of skin side effects related to imatinib mesylate treatment.

  5. Distinct polymorphic variants of the IL-31 gene may be involved in the patho-genesis of mastocytosis, and IL-31 may be involved in the induction of pruritus in patients with mastocytosis.

  6. Serum/pleural fluid IL-31 levels are elevated in tuberculous pleural effusion.

  7. both SCF (show KITLG Proteins) and IL-31 play an important role in mediating inflammation and enhancing severity of atopic asthma.

  8. IL-31 affects keratinocyte differentiation in multiple ways and the IL-1 (show IL1A Proteins) cytokine network is a major downstream effector of IL-31 signaling in deregulating the physical skin barrier.

  9. Oncostatin M (show OSM Proteins) and interleukin-31: Cytokines, receptors, signal transduction and physiology.

  10. The results of our analyses regarding serum levels and receptor expression do not suggest a central role of IL-31 in Mycosis fungoides/Sezary syndrome pathogenesis.

Mouse (Murine) Interleukin 31 (IL31) interaction partners

  1. Oncostatin M (show OSM Proteins) and interleukin-31: Cytokines, receptors, signal transduction and physiology.

  2. IL-31 upregulates IL-31RA (show IL31RA Proteins) expression in DRG neuron cell bodies, and cutaneous-injected IL-31-induced itching is enhanced by DRG IL-31RA (show IL31RA Proteins) expression in mice

  3. our results suggest a functional cooperation between NFAT1 (show NFAT1 Proteins) and JunB (show JUNB Proteins) in mediating IL-31 gene expression in CD4 (show CD4 Proteins)(+) T cells

  4. Data not only illustrate various functions that cysteines perform during IL-31 biosynthesis and secretion, but also highlight their potential roles in cytokine effector functions.

  5. IL-31 may be involved in promoting the dermatitis and epithelial responses that characterize allergic and non-allergic diseases

  6. IL-31 interaction with IL-31 receptor (IL-31R) is identified in an acute model of T helper cell type 2 inflammation in the lung.

  7. these data provide the first evidence of a function for IL-31-IL-31R interactions in limiting the magnitude of type 2 inflammatory responses within the intestine.

Interleukin 31 (IL31) Protein Profile

Protein Summary

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004

Gene names and symbols associated with Interleukin 31 Proteins (IL31)

  • interleukin 31 (IL31)
  • interleukin 31 (Il31)
  • 1700013B14Rik protein
  • IL-31 protein
  • IL31 protein

Protein level used designations for Interleukin 31 Proteins (IL31)

interleukin 31 , interleukin-31 , IL-31

GENE ID SPECIES
701655 Macaca mulatta
744097 Pan troglodytes
100144624 Sus scrofa
386653 Homo sapiens
76399 Mus musculus
690028 Rattus norvegicus
100302725 Canis lupus familiaris
101903065 Bos taurus
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