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The protein encoded by IL37 is a member of the interleukin 1 cytokine family. Additionally we are shipping Interleukin 37 Proteins (22) and Interleukin 37 Kits (20) and many more products for this protein.
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IL37 itself reduced IL1beta (show IL1B Antibodies), IL6 (show IL6 Antibodies) and IL8 (show IL8 Antibodies) production in osteoarthritis chondrocytes, indicating that IL37 is able to induce a counter-regulatory anti-inflammatory feedback loop in chondrocytes. In addition, IL37 dampens catabolic enzyme expression.
this study shows that IL-37 could decrease both NF-kappaB (show NFKB1 Antibodies) and ICAM-1 (show ICAM1 Antibodies) expression upon TLR2 (show TLR2 Antibodies) activation in human coronary artery endothelial cells, and that this effect may be due to its inhibition on NF-kappaB (show NFKB1 Antibodies)
Results show that elevated plasma IL-37 level and its associations with anti-Sm, anti-RNP (show RNPC3 Antibodies) and C3 in systemic lupus erythematosus patients suggest that IL-37 may be implicated in this disease.
CCL22 (show CCL22 Antibodies) and IL-37 with a co-localization in the A549 cells inhibited the proliferation
These fi ndings suggest that elevation of HLA-G (show HLAG Antibodies) and IL-37 in hepatitis C virus may play an important role in response to combined therapy with interferon (show IFNA Antibodies)-apha and ribovirin.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
, IL-1 zeta
, IL-1F7b (IL-1H4, IL-1H, IL-1RP1)
, IL-1X protein
, IL1F7 (canonical product IL-1F7b)
, interleukin 1 family member 7
, interleukin 1, zeta
, interleukin-1 homolog 4
, interleukin-1 superfamily z
, interleukin-1-related protein