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IL-6 signal transducing molecule [RGD, Feb 2006].. Additionally we are shipping IL6ST Kits (8) and IL6ST Proteins (3) and many more products for this protein.
Showing 10 out of 21 products:
The expression of IL-6 (show IL6 Antibodies), IL-6R and gp130 transcripts were detected very early, increased during the first week of life and were predominantly expressed in the head, epidermis and neuromasts of the anterior and posterior lateral line system.
IL-6 (show IL6 Antibodies)/gp130 (show LRPPRC Antibodies) signalling in the osteoclast is not essential for normal bone resorption in vivo, but maintains both trabecular and periosteal bone formation in male mice by promoting osteoblast activity through the stimulation of osteoclast-derived coupling factors and osteotransmitters
gp130 (show LRPPRC Antibodies)-mediated adipose tissue lipolysis promotes hepatic steatosis and insulin (show INS Antibodies) resistance.
differences exist in the expression of receptors utilized by the IL-6 (show IL6 Antibodies)/gp130 (show LRPPRC Antibodies) family of cytokines in astrocytes and microglia, and (2) the findings provide a molecular basis for the differential response to oncostatin M (show OSM Antibodies) by astrocytes versus microglia
Deregulation of gp130 (show LRPPRC Antibodies)/STAT3 (show STAT3 Antibodies) signalling augments the acute phase reponse and macrophage infiltration during atherosclerosis without impacting on the development of aortic plaques.
Significant differential expression (both increases and decreases) of multiple IL-6 (show IL6 Antibodies)/gp130 (show LRPPRC Antibodies) cytokines, such as LIF (show LIF Antibodies), oncostatin-M (show OSM Antibodies), and ciliary neurotrophic factor (show CNTF Antibodies), occurred after Muller cell ablation
GP130 (show LRPPRC Antibodies) signaling collaborated with MYC (show MYC Antibodies) to induce MM and was responsible and sufficient for directing the plasma cell phenotype.
gp130 (show LRPPRC Antibodies), a co-receptor for IL-6 (show IL6 Antibodies) cytokines, triggers activation of YAP (show YAP1 Antibodies) and Notch (show NOTCH1 Antibodies), transcriptional regulators that control tissue growth and regeneration, independently of the gp130 (show LRPPRC Antibodies) effector STAT3 (show STAT3 Antibodies)
osteocytic gp130 (show LRPPRC Antibodies) signaling is required for normal trabecular bone mass and proper cortical bone composition.
PGF2alpha inhibits adipocyte differentiation by means of an IL-11 (show IL11 Antibodies) mediated autocrine negative feedback loop, that acts via gp130 (show LRPPRC Antibodies) to block adipogenesis through the essential actions of the STAT1 (show STAT1 Antibodies) transcription factor.
Osteocytic gp130 (show LRPPRC Antibodies) is required to maintain PTH1R (show PTH1R Antibodies) expression in the osteoblast lineage, and for the stimulation of osteoblast differentiation that occurs in response to PTH (show PTH Antibodies).
IL-6sR and gp130 (show ANPEP Antibodies), but not IL-6R alpha (show IL6R Antibodies), play important roles in regulation of granulosa cell survival
IL-15 (show IL15 Antibodies) alone, similarly to IL-18 (show IL18 Antibodies), has no significant ability for regulation of both soluble IL-6 (show IL6 Antibodies) receptors, sIL (show PMEL Antibodies)-6R and sgp130, released by human neutrophils.
IL-6 signal transducing molecule
interleukin-6 receptor subunit beta
, interleukin 6 signal transducer
, IL-6 receptor subunit beta
, IL-6R subunit beta
, interleukin-6 signal transducer
, membrane glycoprotein 130
, oncostatin-M receptor subunit alpha
, glycoprotein 130