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Interleukin 6 Signal Transducer Proteins (IL6ST)

IL-6 signal transducing molecule [RGD, Feb 2006].. Additionally we are shipping IL6ST Antibodies (21) and IL6ST Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL6ST 16195 Q00560
Rat IL6ST IL6ST 25205  
IL6ST 4827  
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Top IL6ST Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag,Fc Tag 100 μg Log in to see 2 to 3 Days
$319.00
Details
HOST_HEK-293 Cells Mouse Fc Tag 100 μg Log in to see 11 Days
$319.00
Details

IL6ST Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human

Top referenced IL6ST Proteins

  1. Mouse (Murine) IL6ST Protein expressed in HEK-293 Cells - ABIN2181397 : Tanaka, Hara, Copeland, Gilbert, Jenkins, Miyajima: Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit. in Blood 1999 (PubMed)
    Show all 3 references for ABIN2181397

  2. Human IL6ST Protein expressed in HEK-293 Cells - ABIN2181395 : Saito, Yoshida, Hibi, Taga, Kishimoto: Molecular cloning of a murine IL-6 receptor-associated signal transducer, gp130, and its regulated expression in vivo. in Journal of immunology (Baltimore, Md. : 1950) 1992 (PubMed)
    Show all 3 references for ABIN2181395

More Proteins for Interleukin 6 Signal Transducer (IL6ST) Interaction Partners

Zebrafish Interleukin 6 Signal Transducer (IL6ST) interaction partners

  1. The expression of IL-6 (show IL6 Proteins), IL-6R and gp130 transcripts were detected very early, increased during the first week of life and were predominantly expressed in the head, epidermis and neuromasts of the anterior and posterior lateral line system.

Mouse (Murine) Interleukin 6 Signal Transducer (IL6ST) interaction partners

  1. IL-6 (show IL6 Proteins)/gp130 (show LRPPRC Proteins) signalling in the osteoclast is not essential for normal bone resorption in vivo, but maintains both trabecular and periosteal bone formation in male mice by promoting osteoblast activity through the stimulation of osteoclast-derived coupling factors and osteotransmitters

  2. gp130 (show LRPPRC Proteins)-mediated adipose tissue lipolysis promotes hepatic steatosis and insulin (show INS Proteins) resistance.

  3. differences exist in the expression of receptors utilized by the IL-6 (show IL6 Proteins)/gp130 (show LRPPRC Proteins) family of cytokines in astrocytes and microglia, and (2) the findings provide a molecular basis for the differential response to oncostatin M (show OSM Proteins) by astrocytes versus microglia

  4. Deregulation of gp130 (show LRPPRC Proteins)/STAT3 (show STAT3 Proteins) signalling augments the acute phase reponse and macrophage infiltration during atherosclerosis without impacting on the development of aortic plaques.

  5. Significant differential expression (both increases and decreases) of multiple IL-6 (show IL6 Proteins)/gp130 (show LRPPRC Proteins) cytokines, such as LIF (show LIF Proteins), oncostatin-M (show OSM Proteins), and ciliary neurotrophic factor (show CNTF Proteins), occurred after Muller cell ablation

  6. GP130 (show LRPPRC Proteins) signaling collaborated with MYC (show MYC Proteins) to induce MM and was responsible and sufficient for directing the plasma cell phenotype.

  7. gp130 (show LRPPRC Proteins), a co-receptor for IL-6 (show IL6 Proteins) cytokines, triggers activation of YAP (show YAP1 Proteins) and Notch (show NOTCH1 Proteins), transcriptional regulators that control tissue growth and regeneration, independently of the gp130 (show LRPPRC Proteins) effector STAT3 (show STAT3 Proteins)

  8. osteocytic gp130 (show LRPPRC Proteins) signaling is required for normal trabecular bone mass and proper cortical bone composition.

  9. PGF2alpha inhibits adipocyte differentiation by means of an IL-11 (show IL11 Proteins) mediated autocrine negative feedback loop, that acts via gp130 (show LRPPRC Proteins) to block adipogenesis through the essential actions of the STAT1 (show STAT1 Proteins) transcription factor.

  10. Osteocytic gp130 (show LRPPRC Proteins) is required to maintain PTH1R (show PTH1R Proteins) expression in the osteoblast lineage, and for the stimulation of osteoblast differentiation that occurs in response to PTH (show PTH Proteins).

Pig (Porcine) Interleukin 6 Signal Transducer (IL6ST) interaction partners

  1. IL-6sR and gp130 (show ANPEP Proteins), but not IL-6R alpha (show IL6R Proteins), play important roles in regulation of granulosa cell survival

Human Interleukin 6 Signal Transducer (IL6ST) interaction partners

  1. IL-15 alone, similarly to IL-18, has no significant ability for regulation of both soluble IL-6 receptors, sIL-6R and sgp130, released by human neutrophils.

IL6ST Protein Profile

Protein Summary

IL-6 signal transducing molecule

Gene names and symbols associated with IL6ST

  • interleukin 6 signal transducer (il6st)
  • interleukin 6 signal transducer (LOC100349330)
  • interleukin 6 signal transducer (Il6st)
  • interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST)
  • neutrophil migration (NM)
  • 5133400A03Rik protein
  • AA389424 protein
  • Ac1055 protein
  • BB405851 protein
  • CD130 protein
  • D13Ertd699e protein
  • GP130 protein
  • Il-6rb protein
  • NCR protein

Protein level used designations for IL6ST

interleukin-6 receptor subunit beta , interleukin 6 signal transducer , IL-6 receptor subunit beta , IL-6R subunit beta , IL-6R-beta , IL-6RB , interleukin-6 signal transducer , membrane glycoprotein 130 , oncostatin-M receptor subunit alpha , glycoprotein 130

GENE ID SPECIES
100006778 Danio rerio
100349330 Oryctolagus cuniculus
16195 Mus musculus
25205 Rattus norvegicus
395684 Gallus gallus
403545 Canis lupus familiaris
100037294 Sus scrofa
4827 Homo sapiens
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