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Interleukin 6 Signal Transducer Proteins (IL6ST)

IL-6 signal transducing molecule [RGD, Feb 2006].. Additionally we are shipping IL6ST Antibodies (43) and IL6ST Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL6ST 16195 Q00560
Rat IL6ST IL6ST 25205  
Human IL6ST IL6ST 4827  
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Top IL6ST Proteins at

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Mouse His tag Mouse gp130, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 11 Days

IL6ST Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Top referenced IL6ST Proteins

  1. Mouse (Murine) IL6ST Protein expressed in HEK-293 Cells - ABIN2181397 : Tanaka, Hara, Copeland, Gilbert, Jenkins, Miyajima: Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit. in Blood 1999 (PubMed)
    Show all 3 references for ABIN2181397

More Proteins for Interleukin 6 Signal Transducer (IL6ST) Interaction Partners

Zebrafish Interleukin 6 Signal Transducer (IL6ST) interaction partners

  1. The expression of IL-6 (show IL6 Proteins), IL-6R and gp130 transcripts were detected very early, increased during the first week of life and were predominantly expressed in the head, epidermis and neuromasts of the anterior and posterior lateral line system.

Mouse (Murine) Interleukin 6 Signal Transducer (IL6ST) interaction partners

  1. C2C12 myotubes possesses a mechanism for regulating IL-6R and gp130 (show LRPPRC Proteins) expression following lipoic acid treatment or heat shock.

  2. Results suggest that the protective role of gp130 (show LRPPRC Proteins)-dependent STAT3 (show STAT3 Proteins) activation in experimental colitis involves the expansion and activation of mucosal myeloid-derived suppressor cells.

  3. IL-6 (show IL6 Proteins)/gp130 (show LRPPRC Proteins) signalling in the osteoclast is not essential for normal bone resorption in vivo, but maintains both trabecular and periosteal bone formation in male mice by promoting osteoblast activity through the stimulation of osteoclast-derived coupling factors and osteotransmitters

  4. gp130 (show LRPPRC Proteins)-mediated adipose tissue lipolysis promotes hepatic steatosis and insulin (show INS Proteins) resistance.

  5. differences exist in the expression of receptors utilized by the IL-6 (show IL6 Proteins)/gp130 (show LRPPRC Proteins) family of cytokines in astrocytes and microglia, and (2) the findings provide a molecular basis for the differential response to oncostatin M (show OSM Proteins) by astrocytes versus microglia

  6. Deregulation of gp130 (show LRPPRC Proteins)/STAT3 (show STAT3 Proteins) signalling augments the acute phase reponse and macrophage infiltration during atherosclerosis without impacting on the development of aortic plaques.

  7. Significant differential expression (both increases and decreases) of multiple IL-6 (show IL6 Proteins)/gp130 (show LRPPRC Proteins) cytokines, such as LIF (show LIF Proteins), oncostatin-M (show OSM Proteins), and ciliary neurotrophic factor (show CNTF Proteins), occurred after Muller cell ablation

  8. GP130 (show LRPPRC Proteins) signaling collaborated with MYC (show MYC Proteins) to induce MM and was responsible and sufficient for directing the plasma cell phenotype.

  9. gp130 (show LRPPRC Proteins), a co-receptor for IL-6 (show IL6 Proteins) cytokines, triggers activation of YAP (show YAP1 Proteins) and Notch (show NOTCH1 Proteins), transcriptional regulators that control tissue growth and regeneration, independently of the gp130 (show LRPPRC Proteins) effector STAT3 (show STAT3 Proteins)

  10. osteocytic gp130 (show LRPPRC Proteins) signaling is required for normal trabecular bone mass and proper cortical bone composition.

Pig (Porcine) Interleukin 6 Signal Transducer (IL6ST) interaction partners

  1. IL-6sR and gp130 (show ANPEP Proteins), but not IL-6R alpha (show IL6R Proteins), play important roles in regulation of granulosa cell survival

Human Interleukin 6 Signal Transducer (IL6ST) interaction partners

  1. IL-15 alone, similarly to IL-18, has no significant ability for regulation of both soluble IL-6 receptors, sIL-6R and sgp130, released by human neutrophils.

IL6ST Protein Profile

Protein Summary

IL-6 signal transducing molecule

Gene names and symbols associated with IL6ST

  • interleukin 6 signal transducer (il6st)
  • interleukin 6 signal transducer (LOC100349330)
  • interleukin 6 signal transducer (Il6st)
  • interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST)
  • neutrophil migration (NM)
  • 5133400A03Rik protein
  • AA389424 protein
  • Ac1055 protein
  • BB405851 protein
  • CD130 protein
  • D13Ertd699e protein
  • GP130 protein
  • Il-6rb protein
  • NCR protein

Protein level used designations for IL6ST

interleukin-6 receptor subunit beta , interleukin 6 signal transducer , IL-6 receptor subunit beta , IL-6R subunit beta , IL-6R-beta , IL-6RB , interleukin-6 signal transducer , membrane glycoprotein 130 , oncostatin-M receptor subunit alpha , glycoprotein 130

100006778 Danio rerio
100349330 Oryctolagus cuniculus
16195 Mus musculus
25205 Rattus norvegicus
395684 Gallus gallus
403545 Canis lupus familiaris
100037294 Sus scrofa
4827 Homo sapiens
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