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anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) Antibodies

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Additionally we are shipping Internexin Neuronal Intermediate Filament Protein, alpha Kits (8) and Internexin Neuronal Intermediate Filament Protein, alpha Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
INA 9118 Q16352
INA 226180 P46660
INA 24503 P23565
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Top anti-Internexin Neuronal Intermediate Filament Protein, alpha Antibodies at antibodies-online.com

Showing 10 out of 121 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of INA (arrow) using rabbit polyclonal INA Antibody (Center) (ABIN390240). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the INA gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human brain tissue reacted with INA antibody (Center) (ABIN390240), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mammalian Mouse Un-conjugated IHC (fro), IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$357.50
Details
Human Chicken Un-conjugated IHC (fro), IF, WB 0.1 mL Log in to see 6 to 8 Days
$357.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details
Human Chicken Un-conjugated IF, WB   0.1 mL Log in to see 6 to 8 Days
$368.50
Details
Mouse Mouse Un-conjugated IF, IHC (p), WB INA Antibody  western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the INA antibody detected the INA protein (arrow). Confocal immunofluorescent analysis of INA Antibody  with brain tissue followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti NF66/alpha Internexin Polyclonal Antibody, Unconjugated (ABIN739830) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Mammalian Mouse Un-conjugated IF, IHC, WB 100 μL Log in to see 6 to 11 Days
$412.86
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$369.79
Details

INA Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Internexin Neuronal Intermediate Filament Protein, alpha Antibodies

  1. Human Polyclonal INA Primary Antibody for IHC (fro), IF - ABIN372587 : Rajasalu, Teesalu, Janmey, Uibo: Demonstration of natural autoantibodies against the neurofilament protein alpha-internexin in sera of patients with endocrine autoimmunity and healthy individuals. in Immunology letters 2004 (PubMed)
    Show all 5 references for ABIN372587

  2. Mammalian Monoclonal INA Primary Antibody for IHC (fro), IF - ABIN371820 : Pachter, Liem: alpha-Internexin, a 66-kD intermediate filament-binding protein from mammalian central nervous tissues. in The Journal of cell biology 1985 (PubMed)
    Show all 3 references for ABIN371820

  3. Human Polyclonal INA Primary Antibody for EIA, IHC (p) - ABIN358797 : Armstrong, Cairns: Topography of alpha-internexin-positive neuronal aggregates in 10 patients with neuronal intermediate filament inclusion disease. in European journal of neurology : the official journal of the European Federation of Neurological Societies 2006 (PubMed)
    Show all 3 references for ABIN358797

  4. Human Polyclonal INA Primary Antibody for IF, WB - ABIN488084 : Josephs, Holton, Rossor, Braendgaard, Ozawa, Fox, Petersen, Pearl, Ganguly, Rosa, Laursen, Parisi, Waldemar, Quinn, Dickson, Revesz: Neurofilament inclusion body disease: a new proteinopathy? in Brain : a journal of neurology 2003 (PubMed)
    Show all 2 references for ABIN488084

  5. Human Polyclonal INA Primary Antibody for WB - ABIN871738 : Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. in Science (New York, N.Y.) 2007 (PubMed)

  6. Human Polyclonal INA Primary Antibody for IHC (p), WB - ABIN390240 : Cairns, Zhukareva, Uryu, Zhang, Bigio, Mackenzie, Gearing, Duyckaerts, Yokoo, Nakazato, Jaros, Perry, Lee, Trojanowski: alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. in The American journal of pathology 2004 (PubMed)

More Antibodies against Internexin Neuronal Intermediate Filament Protein, alpha Interaction Partners

Human Internexin Neuronal Intermediate Filament Protein, alpha (INA) interaction partners

  1. Gonadotropinomas, null cell pituitary adenomas, and thyrotropinomas exhibit high levels of intracellular INA protein indicating neuronal transdifferentiation.

  2. alpha-Internexin was expressed in 53% of 350 pancreatic neuroendocrine tumors. Reduced expression of alpha-internexin was significantly associated with advanced stage metastases, recurrence and shorter overall survival.

  3. High INA expression is associated with grade II gliomas.

  4. INA may provide additional biologic information relevant to delineation of both pancreatic neuroendocrine neoplasms (NEN) tumor phenotypes and clinical behavior.

  5. the importance of alpha-internexin and NF-L (show NEFL Antibodies) in regulating the conformations of NF-M (show NEFM Antibodies) and NF-H (show NEFH Antibodies)

  6. alpha-internexin expression in neuroblastoma (show ARHGEF16 Antibodies)

  7. The discovery of alpha-internexin in the cytoplasmic inclusions implicates novel mechanisms of pathogenesis in inclusion diseeae and other neurological diseases with pathological accumulations of IFs.

  8. Abnormal neuronal intermediate filament inclusions of alpha-internexin have been identified as the pathological hallmark of neuronal intermediate filament inclusion disease

  9. Expression of the 2 markers, alpha-internexin and peripherin (show PRPH Antibodies), in a small round cell tumor strongly favors the diagnosis of neuroblastoma (show ARHGEF16 Antibodies).

  10. Alpha-Internexin (INA) expression appears to be a simple, reliable prognostic marker and a surrogate marker of 1p19q codeletion.

Mouse (Murine) Internexin Neuronal Intermediate Filament Protein, alpha (INA) interaction partners

  1. Neurofilament light chain (NFL (show NEFL Antibodies)) and neuronal intermediate filament protein (show GFAP Antibodies) alpha-internexin accumulate in axon swellings in the spinal white matter in superoxide dismutase (SOD)-1 (show SOD1 Antibodies) mouse.

  2. Therefore, the cre transgene driven by mouse alpha-internexin promoter, described here, provides a useful animal model to specifically manipulate genes in the developing nervous system.

  3. Alpha-internexin coassembles with all 3 neurofilament proteins into a single network of filaments. All of them are functionally interdependent. It is a fourth subunit of neurofilaments in the adult CNS.

  4. abnormal accumulation of neuronal IFs in the swelling axons and abnormal translocation of alpha-internexin in the nuclei of the spinal motor neurons from dystonia musculorum mice may not directly cause cell death of the spinal motor neurons

  5. RE1 silencing transcription factor (REST) plays a contributory role in the neuron-specific expression of the alpha-internexin, NF-H (show NEFH Antibodies) and NF-M (show CEBPB Antibodies) genes

Internexin Neuronal Intermediate Filament Protein, alpha (INA) Antigen Profile

Protein Summary

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.

Gene names and symbols associated with INA

  • zgc:65851 (zgc:65851) antibody
  • internexin neuronal intermediate filament protein, alpha (ina-A) antibody
  • internexin neuronal intermediate filament protein, alpha (ina-b) antibody
  • internexin neuronal intermediate filament protein, alpha (ina-a) antibody
  • low molecular weight neuronal intermediate filament (nif) antibody
  • internexin neuronal intermediate filament protein, alpha (INA) antibody
  • internexin neuronal intermediate filament protein, alpha a (inaa) antibody
  • internexin neuronal intermediate filament protein, alpha (ina) antibody
  • internexin neuronal intermediate filament protein, alpha (Ina) antibody
  • AV028420 antibody
  • cb126 antibody
  • CTDSPL antibody
  • INA antibody
  • ina-a antibody
  • ina-b antibody
  • Inexa antibody
  • Intlaa antibody
  • MGC53005 antibody
  • MGC69277 antibody
  • MGC82496 antibody
  • NEF5 antibody
  • NF-66 antibody
  • Nf66 antibody
  • sb:cb126 antibody
  • si:ch211-67n3.6 antibody
  • TXBP-1 antibody
  • xefiltin antibody
  • xina antibody
  • XNIF antibody

Protein level used designations for INA

internexin neuronal intermediate filament protein, alpha , intermediate filament protein , low molecular weight neuronal intermediate filament , 66 kDa neurofilament protein , alpha-Inx , alpha-internexin , neurofilament 5 (66kD) , neurofilament-66, tax-binding protein , neurofilament-66 , internexin, alpha

GENE ID SPECIES
321113 Danio rerio
378565 Xenopus laevis
379168 Xenopus laevis
446639 Xenopus laevis
448000 Xenopus (Silurana) tropicalis
450709 Pan troglodytes
555251 Danio rerio
100101732 Xenopus (Silurana) tropicalis
100599632 Nomascus leucogenys
9118 Homo sapiens
226180 Mus musculus
24503 Rattus norvegicus
532236 Bos taurus
486869 Canis lupus familiaris
100153400 Sus scrofa
101085925 Felis catus
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