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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Additionally we are shipping Internexin Neuronal Intermediate Filament Protein, alpha Kits (6) and Internexin Neuronal Intermediate Filament Protein, alpha Proteins (4) and many more products for this protein.
Showing 10 out of 124 products:
Cow (Bovine) Monoclonal INA Primary Antibody for ICC, IF - ABIN152486
Donner, Teshima: Peripheral medulloepithelioma: an immunohistochemical, ultrastructural, and cytogenetic study of a rare, chemotherapy-sensitive, pediatric tumor. in The American journal of surgical pathology 2003
Show all 31 references for ABIN152486
Human Polyclonal INA Primary Antibody for ICC, IF - ABIN152485
Ganns, Schrödl, Neuhuber, Brehmer: Investigation of general and cytoskeletal markers to estimate numbers and proportions of neurons in the human intestine. in Histology and histopathology 2005
Show all 8 references for ABIN152485
Human Polyclonal INA Primary Antibody for IHC (fro), IF - ABIN372587
Rajasalu, Teesalu, Janmey, Uibo: Demonstration of natural autoantibodies against the neurofilament protein alpha-internexin in sera of patients with endocrine autoimmunity and healthy individuals. in Immunology letters 2004
Show all 5 references for ABIN372587
Mammalian Monoclonal INA Primary Antibody for IHC (fro), IF - ABIN371820
Pachter, Liem: alpha-Internexin, a 66-kD intermediate filament-binding protein from mammalian central nervous tissues. in The Journal of cell biology 1985
Show all 3 references for ABIN371820
Human Polyclonal INA Primary Antibody for EIA, IHC (p) - ABIN358797
Armstrong, Cairns: Topography of alpha-internexin-positive neuronal aggregates in 10 patients with neuronal intermediate filament inclusion disease. in European journal of neurology : the official journal of the European Federation of Neurological Societies 2006
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Human Polyclonal INA Primary Antibody for ICC, IF - ABIN4280014
Mulder, Björling, Jonasson, Wernérus, Hober, Hökfelt, Uhlén: Tissue profiling of the mammalian central nervous system using human antibody-based proteomics. in Molecular & cellular proteomics : MCP 2009
Show all 2 references for ABIN4280014
Human Monoclonal INA Primary Antibody for IHC (p), IHC - ABIN152556
Yao, Sumners, ORourke, Sun: Angiotensin II increases GABAB receptor expression in nucleus tractus solitarii of rats. in American journal of physiology. Heart and circulatory physiology 2008
Human Polyclonal INA Primary Antibody for WB - ABIN871738
Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. in Science (New York, N.Y.) 2007
Human Polyclonal INA Primary Antibody for IHC (p), WB - ABIN390240
Cairns, Zhukareva, Uryu, Zhang, Bigio, Mackenzie, Gearing, Duyckaerts, Yokoo, Nakazato, Jaros, Perry, Lee, Trojanowski: alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. in The American journal of pathology 2004
Gonadotropinomas, null cell pituitary adenomas, and thyrotropinomas exhibit high levels of intracellular INA protein indicating neuronal transdifferentiation.
alpha-Internexin was expressed in 53% of 350 pancreatic neuroendocrine tumors. Reduced expression of alpha-internexin was significantly associated with advanced stage metastases, recurrence and shorter overall survival.
High INA expression is associated with grade II gliomas.
INA may provide additional biologic information relevant to delineation of both pancreatic neuroendocrine neoplasms (NEN) tumor phenotypes and clinical behavior.
the importance of alpha-internexin and NF-L (show NEFL Antibodies) in regulating the conformations of NF-M (show NEFM Antibodies) and NF-H (show NEFH Antibodies)
alpha-internexin expression in neuroblastoma (show ARHGEF16 Antibodies)
The discovery of alpha-internexin in the cytoplasmic inclusions implicates novel mechanisms of pathogenesis in inclusion diseeae and other neurological diseases with pathological accumulations of IFs.
Abnormal neuronal intermediate filament inclusions of alpha-internexin have been identified as the pathological hallmark of neuronal intermediate filament inclusion disease
Expression of the 2 markers, alpha-internexin and peripherin (show PRPH Antibodies), in a small round cell tumor strongly favors the diagnosis of neuroblastoma (show ARHGEF16 Antibodies).
Alpha-Internexin (INA) expression appears to be a simple, reliable prognostic marker and a surrogate marker of 1p19q codeletion.
Neurofilament light chain (NFL (show NEFL Antibodies)) and neuronal intermediate filament protein (show GFAP Antibodies) alpha-internexin accumulate in axon swellings in the spinal white matter in superoxide dismutase (SOD)-1 (show SOD1 Antibodies) mouse.
Therefore, the cre transgene driven by mouse alpha-internexin promoter, described here, provides a useful animal model to specifically manipulate genes in the developing nervous system.
Alpha-internexin coassembles with all 3 neurofilament proteins into a single network of filaments. All of them are functionally interdependent. It is a fourth subunit of neurofilaments in the adult CNS.
abnormal accumulation of neuronal IFs in the swelling axons and abnormal translocation of alpha-internexin in the nuclei of the spinal motor neurons from dystonia musculorum mice may not directly cause cell death of the spinal motor neurons
RE1 silencing transcription factor (show REST Antibodies) (REST) plays a contributory role in the neuron-specific expression of the alpha-internexin, NF-H (show NEFH Antibodies) and NF-M (show CEBPB Antibodies) genes
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.
internexin neuronal intermediate filament protein, alpha
, intermediate filament protein
, low molecular weight neuronal intermediate filament
, 66 kDa neurofilament protein
, neurofilament 5 (66kD)
, neurofilament-66, tax-binding protein
, internexin, alpha