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anti-Intestinal Cell (MAK-Like) Kinase (ICK) Antibodies

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. Additionally we are shipping ICK Kits (8) and ICK Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ICK 22858 Q9UPZ9
ICK 56542 Q9JKV2
ICK 84411 Q62726
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Top anti-ICK Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ICK Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using ICK Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells treated with starved 24h, using ICK (Phospho-Tyr159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with PBS 10uM 60', using ICK (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB ICK polyclonal antibody (A01), Lot # 051103JC01 Western Blot analysis of ICK expression in Y-79 . ICK polyclonal antibody (A01), Lot # CAO0060412QCS1. Western Blot analysis of ICK expression in NIH/3T3. 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details

ICK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ICK Antibodies

  1. Human Polyclonal ICK Primary Antibody for IF, IHC - ABIN1534198 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)

  2. Human Polyclonal ICK Primary Antibody for ELISA, WB - ABIN564945 : Vallesi, Di Pretoro, Ballarini, Apone, Luporini et al.: A novel protein kinase from the ciliate Euplotes raikovi with close structural identity to the mammalian intestinal and male-germ cell kinases: characterization and functional implications in the ... in Protist 2010 (PubMed)

More Antibodies against ICK Interaction Partners

Human Intestinal Cell (MAK-Like) Kinase (ICK) interaction partners

  1. findings suggest that increased ICK expression/activity in response to protein deprivation likely provides a novel protective mechanism to limit apoptosis and support compensatory mucosal growth under nutritional stress.

  2. the expressions of ICK/MAK (show MAK Antibodies)/MOK (show MOK Antibodies) proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  3. In glioblastoma cells with deregulated high levels of CCRK (show CDK20 Antibodies), its depletion restores cilia through ICK and an ICK-related kinase MAK (show MAK Antibodies), thereby inhibiting glioblastoma cell proliferation.

  4. High ICK expression is associated with prostate cancer.

  5. an important role for ICK in modulating the activity of mTORC1 through phosphorylation of Raptor (show RPTOR Antibodies) Thr (show TRH Antibodies)-908.

  6. ICK may play a role in the development of multiple organ systems. R272Q has been associated with endocrine-cerebro-osteodysplasia and may explain loss of function since the R272Q mutant fails to localize at the nucleus and has diminished kinase activity

  7. ICK plays an important role in the regulation of proliferation and differentiation of intestinal epithelial cells. ICK may control G1 cell cycle progression by regulating expression of cell cycle regulators cyclin D1 (show CCND1 Antibodies), c-Myc (show MYC Antibodies) and p21Cip1 (show CDKN1A Antibodies).

  8. ICK and FBX9 (show FBXO9 Antibodies) are divergently transcribed from a bidirectional promoter that is GC-rich (show RELB Antibodies) and contains a CpG island.

  9. PP5 (protein phosphatase 5)and CCRK (cell cycle-related kinase (show CDK20 Antibodies)) are yin-yang regulators of T157 phosphorylation. ICK interacts with and phosphorylates human Scythe (show BAT3 Antibodies), an essential regulator of proliferation and apoptosis during mammalian development.

  10. ICK is the prototype for a new group of MAPK (show MAPK1 Antibodies)-like kinases requiring dual phosphorylation at TDY (show SRY Antibodies) motifs.

Mouse (Murine) Intestinal Cell (MAK-Like) Kinase (ICK) interaction partners

  1. findings suggest that increased ICK expression/activity in response to protein deprivation likely provides a novel protective mechanism to limit apoptosis and support compensatory mucosal growth under nutritional stress.

  2. the expressions of ICK/MAK (show MAK Antibodies)/MOK proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  3. Data indicate that ciliary defects caused by a lack of functional intestinal cell kinase (ICK) leads to abnormal Sonic hedgehog (Shh (show SHH Antibodies)) signaling, resulting in congenital disorders such as endocrine-cerebro-osteodysplasia (ECO) syndrome .

  4. ICK is a Kif3a (show KIF3A Antibodies) kinase and essential for proper ciliogenesis in development by regulating ciliary transport at the tip of cilia.

  5. ICK and FBX9 (show FBXO9 Antibodies) are divergently transcribed from a bidirectional promoter that is GC-rich (show RELB Antibodies) and contains a CpG island.

ICK Antigen Profile

Protein Summary

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

Gene names and symbols associated with ICK

  • intestinal cell (MAK-like) kinase (ICK) antibody
  • intestinal cell (MAK-like) kinase (ick) antibody
  • intestinal cell kinase (Ick) antibody
  • 2210420N10Rik antibody
  • AI848300 antibody
  • ECO antibody
  • ICK antibody
  • LCK2 antibody
  • Mrk antibody

Protein level used designations for ICK

intestinal cell (MAK-like) kinase , intestinal cell kinase , serine/threonine-protein kinase ICK-like , MAK-related kinase , hICK , laryngeal cancer kinase 2 , serine/threonine protein kinase , serine/threonine-protein kinase ICK , mICK , MRK , heart serine-threonine protein kinase

GENE ID SPECIES
421896 Gallus gallus
462772 Pan troglodytes
100014080 Monodelphis domestica
100056645 Equus caballus
100225015 Taeniopygia guttata
100401851 Callithrix jacchus
100451338 Pongo abelii
100498050 Xenopus (Silurana) tropicalis
100544019 Meleagris gallopavo
100552302 Anolis carolinensis
100582867 Nomascus leucogenys
22858 Homo sapiens
506286 Bos taurus
481843 Canis lupus familiaris
100511822 Sus scrofa
56542 Mus musculus
84411 Rattus norvegicus
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