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anti-Iron-Responsive Element Binding Protein 2 (IREB2) Antibodies

RNA-binding proteins that bind iron-responsive elements (IREs) [RGD, Feb 2006].. Additionally we are shipping IREB2 Kits (15) and IREB2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IREB2 64602 Q811J3
IREB2 64831 Q62751
IREB2 3658 P48200
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Top anti-IREB2 Antibodies at antibodies-online.com

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB IREB2 Antibody (Center) (ABIN656586) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of Hela cells using IREB2 Antibody (Center) Cat.-No AP52232PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with IREB2 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rabbit Un-conjugated GS, ICC, IF, IHC, IHC (p), WB Western Blot: IRP2 Antibody [ABIN151305] - Detection of IRP2 in RAW 264.7 lysate using ABIN151305. Lane 1: Lot B Lane 2: Lot C Raw macrophages (mouse) were either left untreated (lane 1) or treated overnight with 100mM DFO (lane 2) or 100mM hemin (lane 3). Proteins extracts were subjected to western blotting using IRP2 or b-actin antibodies diluted 1:500 in TBS-Tween. 0.025 mL Log in to see 5 to 7 Days
$178.50
Details
Human Rabbit Un-conjugated ICC, IF, WB 0.1 mL Log in to see 5 to 7 Days
$391.13
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

IREB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-IREB2 Antibodies

  1. Human Polyclonal IREB2 Primary Antibody for FACS, IHC (p) - ABIN656586 : Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. in Molecular human reproduction 2010 (PubMed)
    Show all 5 references for ABIN656586

  2. Human Polyclonal IREB2 Primary Antibody for EIA, FACS - ABIN952944 : Hansen, Xiao, Rice, Bracci, Wrensch, Sison, Chang, Smirnov, Patoka, Seldin, Quesenberry, Kelsey, Wiencke: Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans. in Human molecular genetics 2010 (PubMed)
    Show all 5 references for ABIN952944

  3. Human Polyclonal IREB2 Primary Antibody for EIA, IHC (p) - ABIN453972 : Wang, Di, DAgostino, Torti, Torti: Excess capacity of the iron regulatory protein system. in The Journal of biological chemistry 2007 (PubMed)

  4. Dog (Canine) Polyclonal IREB2 Primary Antibody for WB - ABIN2778884 : Zumbrennen, Hanson, Leibold: HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells. in Biochimica et biophysica acta 2008 (PubMed)

More Antibodies against IREB2 Interaction Partners

Mouse (Murine) Iron-Responsive Element Binding Protein 2 (IREB2) interaction partners

  1. The Irp2(-/-) mice develop microcytic anemia, erythropoietic protoporphyria (show FECH Antibodies) and a progressive neurological disorder, indicating that Irp2 has important functions in the nervous system and erythropoietic homeostasis

  2. Irp2 mRNA transcription is promoted by circadian clock genes, including BMAL1 (show ARNTL Antibodies), and the CLOCK heterodimer.

  3. Irp2 increased mitochondrial iron loading and levels of cytochrome c oxidase, which led to mitochondrial dysfunction and subsequent experimental COPD.

  4. IRP1 (show ACO1 Antibodies) and IRP2 mutant mice rapidly succumb to systemic infection with Salmonella Typhimurium, a pathogenic bacterium that multiplies within macrophages, with increased bacterial burdens in liver and spleen.

  5. aged Irp2-/- mice show marked iron deposition in white matter and in oligodendrocytes while iron content is significantly reduced in neurons. mice show impairments in locomotion, exploration, motor coordination/balance and nociception .

  6. misregulation of iron metabolism from loss of Irp2 causes lower motor neuronal degeneration with significant spinal cord axonopathy

  7. A wide network of mRNAs and proteins with iron-dependent regulation, IRP (show WNT2 Antibodies)-dependent regulation, or both.

  8. The FBXL5 (show FBXL5 Antibodies)-IRP2 axis is integral to control of iron metabolism in vivo.

  9. Iron regulatory protein 1 (show ACO1 Antibodies) outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide.

  10. Mice lacking both IRP2 in their hepatocytes suffer from mitochondrial iron deficiency and dysfunction associated with alterations of the ISC and heme biosynthetic pathways, leading to liver failure and death.

Human Iron-Responsive Element Binding Protein 2 (IREB2) interaction partners

  1. The current results revealed that there was significant association between IREB2 gene rs2568494 polymorphism with susceptibility to Chronic Obstructive Pulmonary Disease.

  2. This study confirms that the IREB2 variants contribute to an increased risk of lung cancer, whereas FAM13A predisposes to increased susceptibility to chronic obstructive pulmonary disease.

  3. IREB2 - candidate gene for Chronic Obstructive Pulmonary Disease identified by Genome-wide association studies.

  4. Irp2 expression is increased in airway epithelial cells exposed to cigarette smoke.

  5. IRP2 can regulate the expression of TfR (show TFRC Antibodies) and Fn by changing its own protein expression and thereby regulate iron metabolism.

  6. Genetic variants near IREB2 and GALC (show GALC Antibodies) likely contribute to genetic susceptibility to PAE associated with COPD (show ARCN1 Antibodies).

  7. Haplotypes of IREB2 carrying major alleles of rs2568494 (G), rs2656069 (A), rs10851906 (A), rs965604 (C) and minor alleles of rs1964678 (T), rs12593229 (T) showed negative correlation with lung function amongst South Indian male smokers with COPD (show ARCN1 Antibodies).

  8. Ascorbate-induced up-regulation of cellular ferroportin (show SLC40A1 Antibodies) levels was associated with increased levels of the iron regulatory protein IRP2, and the hypoxia-inducible factor HIF2alpha (show EPAS1 Antibodies).

  9. dysregulation of IRP2 is an early nodal point underlying altered iron metabolism in breast cancer and may contribute to poor outcome of some patients with breast cancer

  10. IREB2 polymorphisms were associated with chronic obstructive pulmonary disease in non-smoking Chinese Han subjects

IREB2 Antigen Profile

Protein Summary

RNA-binding proteins that bind iron-responsive elements (IREs)

Gene names and symbols associated with IREB2

  • iron-responsive element binding protein 2 (IREB2) antibody
  • iron-responsive element binding protein 2 (ireb2) antibody
  • iron-responsive element binding protein 2 (LOC100341900) antibody
  • iron responsive element binding protein 2 (Ireb2) antibody
  • ACO3 antibody
  • D9Ertd85e antibody
  • DKFZp468N047 antibody
  • im:7153062 antibody
  • IREB2 antibody
  • IREBP2 antibody
  • IRP2 antibody
  • IRP2AD antibody

Protein level used designations for IREB2

iron-responsive element binding protein 2 , IRP2 , iron regulatory protein 2 , Iron-responsive element-binding protein 2 , iron-responsive element-binding protein 2-like , IRE-BP 2 , iron-responsive element-binding protein 2 , iron-regulatory protein 2

GENE ID SPECIES
467731 Pan troglodytes
539404 Bos taurus
652982 Danio rerio
100012608 Monodelphis domestica
100050493 Equus caballus
100082579 Ornithorhynchus anatinus
100174315 Pongo abelii
100341900 Oryctolagus cuniculus
100380628 Salmo salar
100385776 Callithrix jacchus
100580664 Nomascus leucogenys
64602 Mus musculus
64831 Rattus norvegicus
3658 Homo sapiens
414584 Xenopus laevis
475134 Canis lupus familiaris
100153993 Sus scrofa
427490 Gallus gallus
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