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IRX3 is a member of the Iroquois homeobox gene family (see IRX1\; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Additionally we are shipping IRX3 Proteins (5) and many more products for this protein.
Showing 10 out of 91 products:
Human Polyclonal IRX3 Primary Antibody for WB - ABIN2775581
Lewis, Ross, Strickland, Snyder, Daniel: Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast. in Cell and tissue research 1999
Human Polyclonal IRX3 Primary Antibody for IHC (p), WB - ABIN658470
Ragvin, Moro, Fredman, Navratilova, Drivenes, Engström, Alonso, de la Calle Mustienes, Gómez Skarmeta, Tavares, Casares, Manzanares, van Heyningen, Molven, Njølstad, Argenton, Lenhard, Becker: Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. in Proceedings of the National Academy of Sciences of the United States of America 2010
Cow (Bovine) Polyclonal IRX3 Primary Antibody for WB - ABIN2779862
Sun, Hafler, Kaing, Kitada, Ligon, Widlund, Yuk, Stiles, Rowitch: Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. in Developmental biology 2006
This is the first study to reveal that genetic variants of both FTO and IRX3 genes are in high linkage disequilibrium (LD) and are associated with obesity risk in North Indians.
Strategies to pharmacologically regulate Irx3 function in adult endothelial cells may provide new therapies for angiogenesis.
data suggest that IRX3 is a functional long-range target of obesity-associated variants within FTO (show FTO Antibodies) and represents a novel determinant of body mass and composition
IRX3 function may have a direct functional relationship to both obesity and type 2 diabetes.
barH-like homeobox-2 (show BARHL2 Antibodies) gene barhl2 (show BARHL2 Antibodies) acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal (show CAD Antibodies) forebrain signaling center induced by Sonic Hedgehog (show SHH Antibodies)
Irx3 is transcriptionally induced by the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway during anteroposterior patterning of the neural axis.
Irx3 is the first gene known to be necessary and sufficient to specify nephron segment fate in vivo.
Irx3 is necessary for the postnatal maturation of the VCS (show EDC4 Antibodies), possibly via its interactions with Tbx5 (show TBX5 Antibodies) and Nkx2.5 (show NKX2-5 Antibodies).
Irx3 and Irx5 (Irx3/5) are essential in the initiating limb bud to specify progenitors of the femur, tibia, and digit 1.
postnatal Irx3 activity can be repressed by Irx5 (show IRX5 Antibodies)
Irx3 is critical for efficient conduction in this specialized tissue by antithetically regulating two gap junction-forming connexins
Irx3 signal is restricted to the somatic cell component of XX gonads and is present at a discreet period of ovarian development that ends at birth.
IRX3 is a member of the Iroquois homeobox gene family (see IRX1\; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998
iroquois homeobox protein 3
, iroquois-class homeodomain protein IRX-3
, Iroquois related homeobox 3
, homeodomain protein IRXB1
, iroquois-class homeodomain protein IRX-1
, Iroquois homeobox protein 3
, homeobox transcription factor iroquois 3
, iroquois type homeobox
, iroquois-class homeodomain protein irx-3