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anti-Islet Cell Autoantigen 1, 69kDa (ICA1) Antibodies

ICA1 encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. Additionally we are shipping Islet Cell Autoantigen 1, 69kDa Proteins (14) and Islet Cell Autoantigen 1, 69kDa Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ICA1 15893 P97411
ICA1 81024  
ICA1 3382 Q05084
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Top anti-Islet Cell Autoantigen 1, 69kDa Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ICA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ICA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ICA1 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). This demonstrates the ICA1 antibody detected the ICA1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ICA1 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Mouse Rabbit Un-conjugated WB Anti- ICA1 Picoband antibody, Western blotting All lanes: Anti ICA1  at 0.5ug/ml Lane 1: Rat Brain Tissue Lysate at 50ug Lane 2: Mouse Pancreas Tissue Lysate at 50ug Predicted bind size: 55KD Observed bind size: 55KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB ICA1 Antibody (N-term)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ICA1 antibody detected the ICA1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB Human, Heart: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB ICA1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

ICA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Islet Cell Autoantigen 1, 69kDa Antibodies

  1. Human Monoclonal ICA1 Primary Antibody for ELISA, WB - ABIN396747 : Jin, Birlea, Fain, Mailloux, Riccardi, Gowan, Holland, Bennett, Wallace, McCormack, Kemp, Gawkrodger, Weetman, Picardo, Leone, Taïeb, Jouary, Ezzedine, van Geel, Lambert, Overbeck, Spritz: Common variants in FOXP1 are associated with generalized vitiligo. in Nature genetics 2010 (PubMed)
    Show all 5 references for ABIN396747

  2. Chicken Polyclonal ICA1 Primary Antibody for WB - ABIN2785861 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

More Antibodies against Islet Cell Autoantigen 1, 69kDa Interaction Partners

Mouse (Murine) Islet Cell Autoantigen 1, 69kDa (ICA1) interaction partners

  1. ICA69 deficiency promoted formalin-induced long-lasting pain hypersensitivity.

  2. direct link between compromised thymic ICA69 expression and autoimmunity against multiple ICA69-expressing organs, and identify a potential novel mechanism for the development of multi-organ autoimmune diseases.

  3. C-terminal domain of ICA69 interacts with PICK1 (show PICK1 Antibodies) and acts on trafficking of PICK1 (show PICK1 Antibodies)-PKCalpha (show PKCa Antibodies) complex and cerebellar plasticity.

  4. PICK1 (show PICK1 Antibodies) and ICA69 are key regulators of the formation and maturation of insulin (show INS Antibodies) granules.

  5. polymorphisms within the NOD Ica1 core promoter may determine AIRE (show AIRE Antibodies)-mediated down-regulation of ICA69 expression in medullary thymic epithelial cells.

  6. ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide

Human Islet Cell Autoantigen 1, 69kDa (ICA1) interaction partners

  1. C-terminal domain of ICA69 interacts with PICK1 (show PICK1 Antibodies) and acts on trafficking of PICK1 (show PICK1 Antibodies)-PKCalpha (show PKCa Antibodies) complex and cerebellar plasticity.

  2. Novel association was found between intraocular pressure and a common variant at 7p21 near to GLCCI1 (show GLCCI1 Antibodies) and ICA1.

  3. polymorphisms within the NOD Ica1 core promoter may determine AIRE (show AIRE Antibodies)-mediated down-regulation of ICA69 expression in medullary thymic epithelial cells.

  4. ICA69 as a novel Rab2 (show RAB2A Antibodies) effector and its role in regulating the early transport of insulin (show INS Antibodies) secretory granule proteins

Islet Cell Autoantigen 1, 69kDa (ICA1) Antigen Profile

Protein Summary

This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with ICA1

  • islet cell autoantigen 1, 69kDa (ica1) antibody
  • islet cell autoantigen 1, 69kDa (ICA1) antibody
  • Islet cell autoantigen 1 (ica69) antibody
  • islet cell autoantigen 1 (ica1) antibody
  • islet cell autoantigen 1 (Ica1) antibody
  • 69kDa antibody
  • DKFZp469G0321 antibody
  • ICA1 antibody
  • Ica69 antibody
  • ICAp69 antibody
  • MGC52730 antibody
  • MGC83241 antibody
  • zgc:92566 antibody

Protein level used designations for ICA1

islet cell autoantigen 1, 69kDa , Islet cell autoantigen 1 , islet cell autoantigen 1-like , 69 kDa islet cell autoantigen , ICAp69 , islet cell autoantigen 1, 69 kDa , islet cell autoantigen p69 , p69 , diabetes mellitus type I autoantigen , islet cell autoantigen 1 , islet cell autoantigen 1 isoform

GENE ID SPECIES
379786 Xenopus laevis
463264 Pan troglodytes
549616 Xenopus (Silurana) tropicalis
695889 Macaca mulatta
100171501 Pongo abelii
100380590 Salmo salar
100402491 Callithrix jacchus
100511342 Sus scrofa
100585518 Nomascus leucogenys
437003 Danio rerio
15893 Mus musculus
81024 Rattus norvegicus
414587 Xenopus laevis
420581 Gallus gallus
3382 Homo sapiens
475242 Canis lupus familiaris
535346 Bos taurus
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