Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) ELISA Kits

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Additionally we are shipping Isocitrate Dehydrogenase 3 (NAD+) beta Antibodies (79) and Isocitrate Dehydrogenase 3 (NAD+) beta Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse IDH3B IDH3B 170718  
Anti-Human IDH3B IDH3B 3420 O43837
Anti-Rat IDH3B IDH3B 94173 Q68FX0
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More ELISA Kits for Isocitrate Dehydrogenase 3 (NAD+) beta Interaction Partners

Human Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) interaction partners

  1. Human NAD-dependent isocitrate dehydrogenase (IDH) is a heterotetrameric mitochondrial enzyme with 2alpha:1beta:1gamma subunit ratio subunits shich share 40-52% identity in amino acid sequence.

  2. IDPm (show IDH2 ELISA Kits) activity appears to be modulated through enzymatic glutathionylation and deglutathionylation during oxidative stress

  3. active sites of the human NAD-IDH are shared between alpha and gamma subunits and between alpha and beta subunits

  4. Asp192 is needed for optimal affinity of IDH (show IDH1 ELISA Kits) beta subunit (show POLG ELISA Kits) for nicotinamide-adenine dinucleotide (NAD) substrate, but is not critical for catalysis.

  5. Homozygous for loss-of-function mutations in IDH3B is associated with retinitis pigmentosa.

  6. The point mutations of isocitrate dehydrogenase (show IDH1 ELISA Kits) are essentially unique to gliomas.

Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) Antigen Profile

Antigen Summary

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with IDH3B

  • isocitrate dehydrogenase 3 (NAD+) beta (IDH3B) antibody
  • isocitrate dehydrogenase 3 (NAD+) beta (idh3b) antibody
  • isocitrate dehydrogenase 3 (NAD+) beta (Idh3b) antibody
  • isocitrate dehydrogenase 3 (NAD+) beta (Idh3B) antibody
  • C78231 antibody
  • H-IDHB antibody
  • IDH1 antibody
  • IDH3 antibody
  • IDH3B antibody
  • MGC79028 antibody
  • RP46 antibody
  • zgc:86647 antibody

Protein level used designations for IDH3B

isocitrate dehydrogenase 3 (NAD+) beta , isocitrate dehydrogenase 3, beta subunit , isocitrate dehydrogenase [NAD] subunit beta, mitochondrial-like , N14A tumor-related protein , isocitrate dehydrogenase 3 beta , NAD(+)-specific ICDH subunit beta , NAD+-specific ICDH , NAD+-specific isocitrate dehydrogenase b subunit , NAD+-specific isocitrate dehydrogenase beta , isocitrate dehydrogenase [NAD] subunit beta, mitochondrial , isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta subunit , isocitric dehydrogenase subunit beta , NAD(+)-dependent isocitrate dehydrogenase subunit 3 , NAD(+)-isocitrate dehydrogenase subunit 1 , mitochondrial NAD+isocitrate dehydrogenase 3 beta variant 2

281842 Bos taurus
443821 Xenopus laevis
458048 Pan troglodytes
100144949 Xenopus (Silurana) tropicalis
100403538 Callithrix jacchus
170718 Mus musculus
3420 Homo sapiens
94173 Rattus norvegicus
613338 Bos taurus
415247 Danio rerio
733641 Sus scrofa
100172344 Pongo abelii
426573 Gallus gallus
477177 Canis lupus familiaris
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