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May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Additionally we are shipping JKAMP Antibodies (19) and JKAMP Kits (5) and many more products for this protein.
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synergistic function of Jnk1 (show MAPK8 Proteins) in haematopoietic cells and hepatocytes might be relevant for the development of chronic liver injury
Expression of DP, a receptor largely retained in the ER, promoted proteasome recruitment by JAMP.
JAMP is an important component for coordinated clearance of misfolded proteins from the endoplasmic reticulum.
RNF5 associates with JAMP in the ER membrane. This association results in Ubc13 (show UBE2N Proteins)-dependent RNF5-mediated noncanonical ubiquitination of JAMP.
Identification and functional characterization of the mouse J (show MAPK8 Proteins)amp ortholog.
JAMP is a membrane-anchored regulator of the duration of JNK1 (show MAPK8 Proteins) activity in response to diverse stress stimuli [JAMP, a Jun N-terminal kinase (show MAPK8 Proteins) 1 (JNK1)-associated membrane protein]
May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (By similarity).
JNK-associated membrane protein
, JNK1-associated membrane protein
, Jun N-terminal kinase 1-associated membrane protein
, medulloblastoma antigen MU-MB-50.4
, medulloblastoma antigen MU-MB-50.4 homolog