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JRK is the human homolog of the mouse jerky gene. Additionally we are shipping JRK Antibodies (3) and many more products for this protein.
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Jerky has a role in epilepsy and consists of tandemly arranged helix-turn-helix/homeodomain-like motifs and binds specific sets of mRNAs
JRK protein associates with a specific chromosomal centromeric locus in the cell cycle G(2) phase.
This gene is the human homolog of the mouse jerky gene. The encoded protein has similarity to several nuclear regulatory proteins, including centromere protein B, suggesting that it might function as a DNA-binding protein. Insertional inactivation of this gene in transgenic mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene, making this gene a strong candidate for CAE. Two transcript variants encoding different isoforms have been found for this gene.
jerky protein homolog
, jerky protein