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Has low protease activity towards poly-ubiquitin chains (in vitro). Additionally we are shipping Josephin Domain Containing 1 Antibodies (14) and many more products for this protein.
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Human JOSD1 Protein expressed in Escherichia coli (E. coli) - ABIN1098419
Weeks, Grasty, Hernandez-Cuebas, Loll: Crystal structure of a Josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activity. in The Journal of biological chemistry 2011
The gain of function studies indicated that Josephin domain containing 1 activate NR5A1 (show NR5A1 Proteins) gene expression.
JosD1, a membrane-associated DUB whose activity is regulated by ubiquitination, helps regulate membrane dynamics, cell motility, and endocytosis.
Has low protease activity towards poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme.
Josephin domain containing 1
, josephin domain-containing protein 1
, josephin domain-containing 1