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Jumonji Domain Containing 5 (JMJD5) ELISA Kits

JMJD5 likely encodes a histone lysine demethylase. Additionally we are shipping Jumonji Domain Containing 5 Antibodies (62) and Jumonji Domain Containing 5 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human JMJD5 JMJD5 79831 Q8N371
Anti-Mouse JMJD5 JMJD5 77035 Q9CXT6
Anti-Rat JMJD5 JMJD5 308976 Q497B8
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More ELISA Kits for Jumonji Domain Containing 5 Interaction Partners

Human Jumonji Domain Containing 5 (JMJD5) interaction partners

  1. Data suggest that JMJD5 partially accumulates on mitotic spindles during mitosis; depletion of JMJD5 results in significant mitotic arrest, spindle assembly defects, and sustained activation of spindle assembly checkpoint.

  2. These results suggest that direct interaction of JMJD5 with HBx facilitates hepatitis B virus replication through the hydroxylase activity of JMJD5.

  3. Suggest JMJD5 as a potential oncogene (show RAB1A ELISA Kits) in colon carcinogenesis.

  4. results reveal that JMJD5 is a novel binding partner of p53 (show TP53 ELISA Kits) and it functions as a positive modulator of cell cycle and cell proliferation mainly through the repression of p53 (show TP53 ELISA Kits) pathway.

  5. we provide genetic and biochemical evidence that the JMJD5/CDKN1A (p21 (show CDKN1A ELISA Kits)) axis is essential to maintaining the short G1 phase which is critical for pluripotency in human embryonic stem cells

  6. RCCD1 and KDM8 form a histone demethylase (show MBD2 ELISA Kits) complex.

  7. These results reveal that the N-terminal domain is essential for the nuclear localization of JMJD5 and its normal enzymatic function towards substrates in the nucleus

  8. Comparison of the structure of JMJD5 with that of FIH (show CASR ELISA Kits), a well characterized protein hydroxylase, reveals that human JMJD5 might function as a protein hydroxylase.

  9. JMJD5 has a role in regulating PKM2 nuclear translocation and reprogramming HIF-1alpha (show HIF1A ELISA Kits)-mediated glucose metabolism

  10. The study reports high-resolution crystal structures of the human JMJD5 catalytic domain in complex with the substrate 2-oxoglutarate (2-OG) and the inhibitor N-oxalylglycine (NOG (show NOG ELISA Kits)).

Mouse (Murine) Jumonji Domain Containing 5 (JMJD5) interaction partners

  1. Data suggest that Jmjd5 partially accumulates on mitotic spindles during mitosis; depletion of Jmjd5 results in significant mitotic arrest, spindle assembly defects, and sustained activation of spindle assembly checkpoint.

  2. Collectively, these data indicate that JMJD5 is essential during embryonal development and a repressor of p53 (show TP53 ELISA Kits) expression. The latter suggests that JMJD5 has oncogenic activity and accordingly JMJD5 is upregulated in leukemias and breast cancer.

  3. Results suggest that Jmjd5 physiologically moderates embryonic cell proliferation through the epigenetic control of Cdkn1a (show CDKN1A ELISA Kits) expression.

Jumonji Domain Containing 5 (JMJD5) Antigen Profile

Antigen Summary

This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with JMJD5

  • jumonji domain containing 5 (JMJD5) antibody
  • jumonji domain containing 5 (PTRG_02386) antibody
  • jumonji domain containing 5 (MCYG_00400) antibody
  • jumonji domain containing 5 (CC1G_13927) antibody
  • jumonji domain containing 5 (PGTG_16928) antibody
  • lysine (K)-specific demethylase 8 (kdm8) antibody
  • jumonji domain containing 5 (KDM8) antibody
  • lysine (K)-specific demethylase 8 (KDM8) antibody
  • lysine (K)-specific demethylase 8 (Kdm8) antibody
  • 3110005O21Rik antibody
  • Jmjd5 antibody
  • RGD1304823 antibody
  • zgc:91962 antibody
  • zgc:173863 antibody

Protein level used designations for JMJD5

jumonji domain containing 5 , JmjC domain-containing protein 5 , Jumonji domain-containing protein 5 , lysine-specific demethylase 8 , jmjC domain-containing protein 5 , jumonji domain-containing protein 5

GENE ID SPECIES
416583 Gallus gallus
6340528 Pyrenophora tritici-repentis Pt-1C-BFP
9225437 Arthroderma otae CBS 113480
9378880 Coprinopsis cinerea okayama7130
10528643 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100158649 Xenopus (Silurana) tropicalis
608058 Canis lupus familiaris
507905 Bos taurus
79831 Homo sapiens
77035 Mus musculus
436936 Danio rerio
308976 Rattus norvegicus
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