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Jun Dimerization Protein 2 Proteins (JDP2)

Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Additionally we are shipping JDP2 Antibodies (19) and JDP2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
JDP2 122953 Q8WYK2
JDP2 81703 P97875
JDP2 116674 Q78E65
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Top JDP2 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,348.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,370.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 9 to 11 Days
$229.85
Details

JDP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Jun Dimerization Protein 2 (JDP2) Interaction Partners

Human Jun Dimerization Protein 2 (JDP2) interaction partners

  1. Preeclamptic plasma induces transcription modifications involving the AP-1 (show FOSB Proteins) transcriptional regulator JDP2 in endothelial cells.

  2. Results suggest that JDP2 is an integral component of the Nrf2-MafK complex and that it modulates antioxidant and detoxification programs by acting via the ARE.

  3. the recruitment of multiple HDAC (show HDAC3 Proteins) members to JDP2 and ATF3 (show ATF3 Proteins) is part of their transcription repression mechanism.

  4. The molecular mechanisms that underlie the action of JDP2 in cellular aging and replicative senescence by mediating the dissociation of polycomb repressive complexes from the p16(Ink4a)/Arf locus are discussed.

  5. JDP2 is crucial to triggering reactivation from latency to lytic replication

  6. JDP2 expression was downregulated in pancreatic carcinoma & this correlated with metastasis & decreased post-surgery survival.

  7. c-Jun dimerization protein 2 inhibits cell transformation and has a role as a tumor suppressor gene

  8. JDP2 is a cellular survival protein whose presence is necessary for normal cellular function

  9. JDP2 acts as a repressor and could be functionally associated with HDAC3 (show HDAC3 Proteins) to inhibit CHOP (show DDIT3 Proteins) transcription

  10. IRF2 (show IRF2 Proteins)-BP1 (show DLX4 Proteins) is a JDP2-binding protein enhancing the polyubiquitination of JDP2 and represses ATF2 (show ATF2 Proteins)-mediated transcriptional activation from a CRE-containing promoter.

Mouse (Murine) Jun Dimerization Protein 2 (JDP2) interaction partners

  1. High JDP2 expression in the bone marrow contributes to metastatic spread in the lung.

  2. results suggest a negative feedback loop between JDP2 and p53 (show TP53 Proteins), and a direct link between JDP2 and a key oncogenic pathway

  3. Tbx3 (show TBX3 Proteins) plays an important role in osteoclastogenesis at least in part by regulating CSF1 (show CSF1 Proteins)-dependent expression of JDP2.

  4. Using transgenic mice overexpressing the AP-1 (show JUN Proteins) inhibitor JDP2, a central role of AP-1 (show JUN Proteins) in the induction of hypertrophy and apoptosis in cardiomyocytes is demonstrated.

  5. Jdp2 transcriptionally regulates the Trp53 (show TP53 Proteins) promoter, via an atypical AP-1 (show JUN Proteins) site, and Jdp2 expression negatively regulates Trp53 (show TP53 Proteins) expression levels; a genetic mechanism for tumour formation in the context of Trp53 (show TP53 Proteins) heterozygosity

  6. the recruitment of multiple HDAC (show HDAC3 Proteins) members to JDP2 and ATF3 (show ATF3 Proteins) is part of their transcription repression mechanism.

  7. Jdp2 plays pivotal roles in in vivo bone homeostasis and host defense by regulating osteoclast and neutrophil differentiation.

  8. JDP2 phosphorylation by JNK (show MAPK8 Proteins) results in rapid JDP2 destabilization and reduced expression levels following various cell stimuli

  9. transcription of the gene for cyclin-A2 (show CCNA2 Proteins) appears to be a direct target of JDP2 in the suppression of cell proliferation

  10. JDP2 expression may play a critical role in liver cancer development.

Zebrafish Jun Dimerization Protein 2 (JDP2) interaction partners

  1. the kinase fragment of DCLK (show DCLK2 Proteins) is translocated into the nucleus upon hyperosmotic stresses and the kinase efficiently phosphorylates JDP2, a possible target in the nucleus, with the aid of histones

JDP2 Protein Profile

Protein Summary

Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

Gene names and symbols associated with JDP2

  • Jun dimerization protein 2 (JDP2)
  • Jun dimerization protein 2 (Jdp2)
  • Jun dimerization protein 2 (jdp2)
  • fk87c02 protein
  • JDP2 protein
  • Jundm2 protein
  • Jundp2 protein
  • TIF protein
  • wu:fk87c02 protein
  • zgc:92851 protein

Protein level used designations for JDP2

Jun dimerization protein 2 , jun dimerization protein 2 , progesterone receptor co-activator , c-Jun dimerization protein 2

GENE ID SPECIES
423363 Gallus gallus
453048 Pan troglodytes
531476 Bos taurus
122953 Homo sapiens
81703 Mus musculus
116674 Rattus norvegicus
436766 Danio rerio
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