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Junctophilin 1 Proteins (JPH1)

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Additionally we are shipping Junctophilin 1 Antibodies (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
JPH1 56704 Q9HDC5
JPH1 57339 Q9ET80
Rat JPH1 JPH1 297748  
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Top Junctophilin 1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

JPH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Junctophilin 1 (JPH1) Interaction Partners

Human Junctophilin 1 (JPH1) interaction partners

  1. Results show that JPH1 and GDAP1 (show GDAP1 Proteins) share a common pathway and depend on each other; therefore, JPH1 can contribute to the phenotypical consequences of GDAP1 (show GDAP1 Proteins) mutations.

  2. This study suggests that genetic variants of JPH1 may modulate the effect of smoking on carotid plaque burden.

  3. This study demonstrates that both JP1 and JP2 (show JPH2 Proteins) in skeletal muscle undergo Ca2 (show CA2 Proteins)+-dependent proteolysis by endogenous proteases when the intracellular Ca2 (show CA2 Proteins)+ is raised within the physiological range for a sustained period

  4. JP1 and JP2 (show JPH2 Proteins) can facilitate the assembly of DHPR (show QDPR Proteins) with other proteins of the excitation-contraction coupling machinery

Mouse (Murine) Junctophilin 1 (JPH1) interaction partners

  1. This study demonstrates that both JP1 and JP2 (show JPH2 Proteins) in skeletal muscle undergo Ca2 (show CA2 Proteins)+-dependent proteolysis by endogenous proteases when the intracellular Ca2 (show CA2 Proteins)+ is raised within the physiological range for a sustained period

  2. JP1 gene is expressed during the whole process of cardiogenesis, while JP1 protein only appears during the early stage.

  3. JP1 and JP2 (show JPH2 Proteins) can facilitate the assembly of DHPR (show QDPR Proteins) with other proteins of the excitation-contraction coupling machinery

  4. an important fraction of resting plasmalemmal Ca(2 (show CA2 Proteins)+) permeability is mediated by the Orai1 (show TMEM132A Proteins) pathway, which contributes to the control of [Ca(2 (show CA2 Proteins)+)](rest) and resting Ca(2 (show CA2 Proteins)+) stores and that this pathway is defective in JP1 KO myotubes

  5. Skeletal muscle JP1/2 damage is significantly associated with early (0-3 days) strength deficits after performance of eccentric contractions.

  6. Abnormal junctional membrane structures in cardiac myocytes in transgenic mice expressing junctophilin type 1.

  7. We report a novel Junctophilin subtype, JP-4 (show JPH4 Proteins), encoded in the human (chromosome 14q11.1) and mouse (chromosome 14C1-2) genomes. JP-4 (show JPH4 Proteins) shares characteristic structural features with other JP subtypes, and is found in the brain.

  8. Junctophilins support the Ca(2 (show CA2 Proteins)+)-mediated communication between voltage-gated Ca(2 (show CA2 Proteins)+) channels, which modulates the excitability of Purkinje cells and is fundamental to cerebellar long-term depression and motor functions.

Junctophilin 1 (JPH1) Protein Profile

Protein Summary

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family.

Gene names and symbols associated with Junctophilin 1 Proteins (JPH1)

  • junctophilin 1 (JPH1)
  • junctophilin 1a (jph1a)
  • junctophilin 1 (jph1)
  • junctophilin 1 (Jph1)
  • mitsugumin72/junctophilin type1 (MG72/JP1)
  • bZ1M12.3 protein
  • ENSMUSG00000054314 protein
  • JP-1 protein
  • Jp1 protein
  • Jph1 protein
  • si:rp71-1m12.3 protein

Protein level used designations for Junctophilin 1 Proteins (JPH1)

junctophilin 1 , junctophilin-1 , junctophilin 1a , junctophilin-1-like , junctophilin type 1 , junctophilin type1 , mitsugumin72 , JP-1 , mg72 , mitsugumin-72

GENE ID SPECIES
420190 Gallus gallus
536811 Bos taurus
561691 Danio rerio
100145273 Xenopus (Silurana) tropicalis
100481708 Ailuropoda melanoleuca
100547979 Meleagris gallopavo
100561435 Anolis carolinensis
100600957 Nomascus leucogenys
56704 Homo sapiens
487001 Canis lupus familiaris
57339 Mus musculus
297748 Rattus norvegicus
100147894 Danio rerio
100008611 Oryctolagus cuniculus
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