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K(lysine) Acetyltransferase 2A (KAT2A) ELISA Kits

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. Additionally we are shipping K(lysine) Acetyltransferase 2A Antibodies (90) and K(lysine) Acetyltransferase 2A Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KAT2A KAT2A 2648 Q92830
Anti-Mouse KAT2A KAT2A 14534 Q9JHD2
Anti-Rat KAT2A KAT2A 303539  
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More ELISA Kits for K(lysine) Acetyltransferase 2A Interaction Partners

Human K(lysine) Acetyltransferase 2A (KAT2A) interaction partners

  1. Suggest lysine acetyltransfer as a potential regulator of platelet actin dynamics, and potential roles for lysine acetylation in the molecular coordination of platelet activation and function.

  2. Data uncover GCN5 as a negative regulator of C/EBPalpha (show CEBPA ELISA Kits) and demonstrate the importance of C/EBPalpha (show CEBPA ELISA Kits) acetylation in myeloid differentiation.

  3. GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 (show STAT3 ELISA Kits) and AKT (show AKT1 ELISA Kits) Signaling Pathways

  4. results thus demonstrate that the catalytic activity of GCN5 is stimulated by subunits of the ADA2a (show TADA2A ELISA Kits)- or ADA2b-containing HAT (show MGEA5 ELISA Kits) modules and is further increased by incorporation of the distinct HAT (show MGEA5 ELISA Kits) modules in the ATAC (show XCL1 ELISA Kits) or SAGA holo-complexes

  5. GCN5 plays a positive role in human colon cancer development, and its suppression holds a great therapeutic potential in antitumor therapy

  6. our results represent the first work demonstrating that GCN5 and PCAF (show KAT2B ELISA Kits) exhibit different functions and antagonistically regulate the XBP-1S-mediated transcription.

  7. Gcn5 and PCAF (show KAT2B ELISA Kits) repress IFN-beta (show IFNB1 ELISA Kits) production in an enzymatic activity-independent and non-transcriptional manner: by inhibiting the innate immune signaling kinase TBK1 (show TBK1 ELISA Kits) in the cytoplasm.

  8. The antifibrotic effects of SIRT1 (show SIRT1 ELISA Kits) in systemic sclerosis were due in part to decreased expression and function of the acetyltransferase p300 (show EP300 ELISA Kits).

  9. DDIT3 (show DDIT3 ELISA Kits) and KAT2A cooperatively up-regulate TNFRSF10A (show TNFRSF10A ELISA Kits) and TNFRSF10B (show TNFRSF10B ELISA Kits).

  10. HBXIP promotes the migration of breast cancer cells through modulating microtubule acetylation mediated by GCN5.

Mouse (Murine) K(lysine) Acetyltransferase 2A (KAT2A) interaction partners

  1. In addition to reducing atrogene expression, surprisingly inhibiting NF-kappaB (show NFKB1 ELISA Kits) with IkappaBalpha (show NFKBIA ELISA Kits)-SR or by GCN5 knockdown in these muscles also enhanced AKT (show AKT1 ELISA Kits) and mechanistic target of rapamycin (mTOR (show FRAP1 ELISA Kits)) activities, which also contributed to the reduction in atrophy.

  2. Gcn5 and PCAF (show KAT2B ELISA Kits) repress IFN-beta (show IFNB1 ELISA Kits) production in an enzymatic activity-independent and non-transcriptional manner: by inhibiting the innate immune signaling kinase TBK1 (show TBK1 ELISA Kits) in the cytoplasm.

  3. GCN5 and HDAC1 (show HDAC1 ELISA Kits) are the crucial enzymes that regulating epigenetic reprogramming; we observed dynamic changes in the expression levels of GCN5 and HDAC1 (show HDAC1 ELISA Kits) during embryo development

  4. In conclusion, these data establish Kat2a as a novel and essential regulator of hippocampal memory consolidation.

  5. Study reveals that Gcn5/PCAF (show KAT2B ELISA Kits) facilitate adipogenesis through regulation of PPARgamma (show PPARG ELISA Kits) expression and regulate brown adipogenesis by influencing Prdm16 (show PRDM16 ELISA Kits) expression.

  6. Sirt6 interacts with and modifies GCN5, enhancing GCN5's activity.

  7. Data support a model in which p23 and GCN5 regulate diverse multistep pathways by controlling the longevity of protein-DNA complexes.

  8. Data have defined an important role for GCN5 in NSC and provided evidence that GCN5 is an important Myc (show MYC ELISA Kits) transcriptional cofactor in vivo.

  9. In the absence of PU.1, there is decreased association of Gcn5 and p300/CBP associated factor and increased association of histone deacetylases at the interleukin (Il)9 locus in T helper (Th)9 cells.

  10. GCN5 as a new negative regulator of transactivation by E1A and suggest that its KAT activity is required for optimal virus replication.

K(lysine) Acetyltransferase 2A (KAT2A) Antigen Profile

Antigen Summary

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009

Gene names and symbols associated with KAT2A

  • K(lysine) acetyltransferase 2A (KAT2A) antibody
  • K(lysine) acetyltransferase 2A (kat2a) antibody
  • K(lysine) acetyltransferase 2A (Kat2a) antibody
  • 1110051E14Rik antibody
  • AW212720 antibody
  • Gcn5 antibody
  • Gcn5l2 antibody
  • hGCN5 antibody
  • KAT2A antibody
  • mmGCN5 antibody
  • PCAF-b antibody

Protein level used designations for KAT2A

histone acetyltransferase KAT2A , general control of amino acid synthesis 5-like 2 , GCN5 general control of amino-acid synthesis 5-like 2 , general control of amino acid synthesis protein 5-like 2 , K(lysine) acetyltransferase 2A , GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 , General control of amino acid synthesis, yeast, homolog-like 2 , STAF97 , histone acetyltransferase GCN5 , hsGCN5 , lysine acetyltransferase 2A , GCN5 general control of amino acid synthesis-like 2 , PCAF-B/GCN5 , general control of amino acid synthesis, yeast homolog-like 2 , general control of amino acid synthesis-like 2

GENE ID SPECIES
552646 Apis mellifera
374232 Gallus gallus
454677 Pan troglodytes
490971 Canis lupus familiaris
100176452 Ciona intestinalis
100597293 Nomascus leucogenys
2648 Homo sapiens
14534 Mus musculus
303539 Rattus norvegicus
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