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K(lysine) Acetyltransferase 6B Proteins (KAT6B)

The protein encoded by KAT6B is a histone acetyltransferase and component of the MOZ/MORF protein complex. Additionally we are shipping KAT6B Antibodies (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KAT6B 23522 Q8WYB5
Mouse KAT6B KAT6B 54169 Q8BRB7
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Top KAT6B Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$365.64
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KAT6B Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for K(lysine) Acetyltransferase 6B (KAT6B) Interaction Partners

Human K(lysine) Acetyltransferase 6B (KAT6B) interaction partners

  1. KAT6B sequence variants are being reported in the Say-Barber-Biesecker type of blepharophimosis mental retardation syndromes (SBBS) and in the more severe genitopatellar syndrome.

  2. This study shown MYST4 to be the risk factor for attention deficit/hyperactivity disorder.

  3. Homozygous deletions of KAT6B and the loss of its mRNA occur in SCLC cell lines and primary tumors. KAT6B loss enhances cancer growth. Restoration induces tumor suppressor-like features involving a new type of histone H3 Lys23 acetyltransferase activity.

  4. The relationship between MYO1C (show MYO1C Proteins) and KAT6B suggests that the two are interacting in chromatin remodelling for gene expression in human masseter muscle. This is the nuclear myosin1 (NM1 (show MYO1C Proteins)) function of MYO1C (show MYO1C Proteins).

  5. Similar to those observed in other genetic disorders resulting from KAT6B mutations.

  6. The study showed that markers rs11001178 (MYST4) showed weak associations.

  7. KAT5 (show KAT5 Proteins) and KAT6B regulate prostate cancer cell growth through PI3K (show PIK3CA Proteins)-AKT (show AKT1 Proteins) signaling.

  8. MORF double PHD (show PDC Proteins) finger binds to Histone H3 (show HIST3H3 Proteins) in a manner that is enhanced by acetylation of the lysine residues K9 and K14 (show KRT14 Proteins)

  9. Our results confirm the implication of KAT6B mutations in typical SBBYS syndrome and emphasize the importance of genotype-phenotype correlations at the KAT6B locus.

  10. These data suggest that the tandem of plant homeodomain 1/2 fingers play a role in MOZ and MORF histone acetyltransferase association with histon H3 regions enriched in acetylated marks.

Cow (Bovine) K(lysine) Acetyltransferase 6B (KAT6B) interaction partners

  1. MYST4 may contribute to important and specific acetylation events occurring during gametes and embryo development

Mouse (Murine) K(lysine) Acetyltransferase 6B (KAT6B) interaction partners

  1. Data indicate that Myst4, Jmjd2b, Aof1 (show KDM1B Proteins) genes are regulated by H3K9me under hyperinsulinemia/hyperglycemia.

  2. Data show that H3 acetylation by Myst4 is important for neural, craniofacial, and skeletal morphogenesis, mainly through its ability to specifically regulating the MAPK (show MAPK1 Proteins) signaling pathway.

  3. Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors.

  4. MORF4 has a role in cellular aging, and MRG15 (show MORF4L1 Proteins) associates with both histone deacetylases and histone acetyl transferase (show HAT1 Proteins) complexes [review]

KAT6B Protein Profile

Protein Summary

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KAT6B

  • K(lysine) acetyltransferase 6B (kat6b)
  • K(lysine) acetyltransferase 6B (KAT6B)
  • K(lysine) acetyltransferase 6B (Kat6b)
  • AI507552 protein
  • B130044K16Rik protein
  • GTPTS protein
  • id:ibd5103 protein
  • mKIAA0383 protein
  • Morf protein
  • MOZ2 protein
  • MYST-4 protein
  • Myst4 protein
  • qkf protein
  • querkopf protein
  • si:dkey-24f15.3 protein
  • ZC2HC6B protein

Protein level used designations for KAT6B

histone acetyltransferase MYST4 , MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4 , MOZ-related factor , MYST histone acetyltransferase (monocytic leukemia) 4 , MYST-4 , histone acetyltransferase KAT6B , histone acetyltransferase MORF , histone acetyltransferase MOZ2 , monocytic leukemia zinc finger protein-related factor , MYST histone acetyltransferase monocytic leukemia 4 , histone acetyltransferase querkopf , monocytic leukemia , protein querkopf

GENE ID SPECIES
568932 Danio rerio
423734 Gallus gallus
23522 Homo sapiens
479254 Canis lupus familiaris
535403 Bos taurus
54169 Mus musculus
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