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anti-K(lysine) Acetyltransferase 8 (KAT8) Antibodies

KAT8 encodes a member of the MYST histone acetylase protein family. Additionally we are shipping K(lysine) Acetyltransferase 8 Kits (4) and K(lysine) Acetyltransferase 8 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KAT8 310194 Q5XI06
KAT8 84148 Q9H7Z6
KAT8 67773 Q9D1P2
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Top anti-K(lysine) Acetyltransferase 8 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MYST1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ICC, IHC, ELISA, WB 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-HMOF/MYST1(C-term) Pab (ABIN387971) in K562 cell line lysates (35 µg/lane). HMOF/MYST1(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with HMOF/MYST1 antibody (C-term) (ABIN387971), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MYST1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$378.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated DB, ICC Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-MYST1 antibody. 50 μg Log in to see 7 to 9 Days
$285.71
Details

KAT8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-K(lysine) Acetyltransferase 8 Antibodies

  1. Human Polyclonal KAT8 Primary Antibody for EIA, IHC (p) - ABIN356666 : Rea, Xouri, Akhtar: Males absent on the first (MOF): from flies to humans. in Oncogene 2007 (PubMed)
    Show all 3 references for ABIN356666

  2. Human Monoclonal KAT8 Primary Antibody for ICC, IHC - ABIN1724671 : Neal, Pannuti, Smith, Lucchesi: A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF. in Biochimica et biophysica acta 2000 (PubMed)
    Show all 3 references for ABIN1724671

  3. Human Monoclonal KAT8 Primary Antibody for IF, IHC (p) - ABIN1108370 : Sterner, Berger: Acetylation of histones and transcription-related factors. in Microbiology and molecular biology reviews : MMBR 2000 (PubMed)
    Show all 2 references for ABIN1108370

  4. Human Polyclonal KAT8 Primary Antibody for WB - ABIN2783663 : Pfister, Rea, Taipale, Mendrzyk, Straub, Ittrich, Thuerigen, Sinn, Akhtar, Lichter: The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma. in International journal of cancer. Journal international du cancer 2008 (PubMed)

More Antibodies against K(lysine) Acetyltransferase 8 Interaction Partners

Human K(lysine) Acetyltransferase 8 (KAT8) interaction partners

  1. MOF is highly enriched in induced pluripotent stem cells (iPSCs), and MOF expression is upregulated during the reprogramming process. The ectopic expression of MOF promotes reprogramming. MOF affects Wdr5 (show WDR5 Antibodies) and endogenous Oct4 (show POU5F1 Antibodies) expression.

  2. Along with the PHF20 (show PHF20 Antibodies)/MOF complex, G9a (show EHMT2 Antibodies) links the crosstalk between ERalpha (show ESR1 Antibodies) methylation and histone acetylation that governs the epigenetic regulation of hormonal gene expression.

  3. Data found downregulation of hMOF in gastric cancer cells and tissues. Declined hMOF expression, but not high level of HDAC4 (show HDAC4 Antibodies), may account for global histone H4K16ac suggesting that loss of hMOF expression may be involved in gastric cancer progression.

  4. EZH2 (enhancer of zeste homolog 2 (show EZH2 Antibodies)) was up-regulated in human oral tongue squamous cell carcinoma tissues and its level positively correlated with level of hMOF.

  5. Mutant MOF-T392A expression abrogates DSB repair in S/G2 (show STRN3 Antibodies) phase cells. MOF-T392A has delayed 53BP1 (show TP53BP1 Antibodies) dissociation and decreased DNA association.

  6. Results show the expression of hMOF mRNA and protein was significantly downregulated in ovarian epithelial cancer tissues, and patients with high hMOF levels showed improved survival as compared to those with low hMOF levels.

  7. The histone acetyltransferase (show HAT Antibodies) hMOF suppresses hepatocellular carcinoma growth by targeting the expression of SIRT6 (show SIRT6 Antibodies).

  8. Functional interactions of MYST1 with androgen receptor (show AR Antibodies) and NF-KB are critical for prostate cancer progression.

  9. hMOF was overexpressed in human non-small cell lung cancer and was a predictor of poor survival.

  10. low expression of hMOF was strongly correlated with tumor differentiation and survival of patients with gastric cancer. While in patients with renal cell carcinoma (show MOK Antibodies), downregulation of hMOF was connected to ccRCC and tissues with T1 tumor status.

Mouse (Murine) K(lysine) Acetyltransferase 8 (KAT8) interaction partners

  1. STAT5B (show STAT5B Antibodies) and MOF work as negative regulators in adipogenesis.

  2. NSL and MSL HAT (show HAT Antibodies) complexes differentially regulate specific sets of expressed genes in mESCs and during differentiation

  3. cardiac-specific MOF overexpression protected mice from transverse aortic constriction-induced cardiac hypertrophy, with reduced radios of heart weight/body weight, decreased left ventricular wall thickness and increased fractional shortening.

  4. Mof plays a critical role in T-cell differentiation and that depletion of Mof in T cells reduces T-cell numbers and, by an undefined mechanism, induces genomic instability in B cells through bystander mechanism.

  5. Depletion of MOF in mouse embryonic stem cells causes a specific decrease in expression of a subset of X-linked genes.

  6. the histone acetyltransferase Mof plays an essential role in the maintenance of ESC self-renewal and pluripotency

  7. PHF20 (show PHF20 Antibodies) is not required for maintaining the global H4K16 acetylation levels or locus specific histone acetylation but instead works downstream in transcriptional regulation of MOF target genes

  8. Purkinje cells (PC)-specific deletion of the mouse males absent on the first (mMof) gene (Cre(-)), which encodes a protein that specifically acetylates histone H4 (show HIST1H4H Antibodies) at lysine 16 (H4K16ac) and influences ATM (show ATM Antibodies) function, is critical for PC longevity.

  9. Msl1 interacts with Msl3 as an extended chain forming an extensive hydrophobic interface, whereas the Msl1-MOF interface involves electrostatic interactions between the HAT domain and a long helix of Msl1.

  10. Data show that loss of Mof leads to reduction of histone H4 (show HIST1H4H Antibodies) K16 (show KRT16 Antibodies) acetylation, cell cycle arrest, chromosome aberration, defects in DNA damage repair, and complete loss of Mdc1 (show MDC1 Antibodies) response to DNA damage.

K(lysine) Acetyltransferase 8 (KAT8) Antigen Profile

Protein Summary

This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KAT8

  • MYST histone acetyltransferase 1 (myst1) antibody
  • K(lysine) acetyltransferase 8 (kat8) antibody
  • K(lysine) acetyltransferase 8 (MYST1) antibody
  • MYST histone acetyltransferase 1 (MYST1) antibody
  • MYST histone acetyltransferase 1 (LOC100341732) antibody
  • K (lysine) acetyltransferase 8 (Kat8) antibody
  • K(lysine) acetyltransferase 8 (KAT8) antibody
  • K(lysine) acetyltransferase 8 (Kat8) antibody
  • 2010203C02Rik antibody
  • 5830450F21Rik antibody
  • D7Ertd629e antibody
  • hMOF antibody
  • MOF antibody
  • MYST1 antibody
  • wu:fb22g02 antibody
  • wu:fj22d09 antibody
  • ZC2HC8 antibody
  • zgc:66387 antibody

Protein level used designations for KAT8

MYST histone acetyltransferase 1 , histone acetyltransferase KAT8 , K(lysine) acetyltransferase 8 , probable histone acetyltransferase MYST1-like , MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 , MYST protein 1 , MYST-1 , lysine acetyltransferase 8 , probable histone acetyltransferase MYST1 , histone acetyltransferase MYST1 , ortholog of Drosophila males absent on the first (MOF) , histone acetyltransferase Myst1

GENE ID SPECIES
548988 Xenopus (Silurana) tropicalis
100003790 Danio rerio
100019305 Monodelphis domestica
100064910 Equus caballus
100341732 Oryctolagus cuniculus
100387289 Callithrix jacchus
100435717 Pongo abelii
100522367 Sus scrofa
100593658 Nomascus leucogenys
310194 Rattus norvegicus
84148 Homo sapiens
67773 Mus musculus
479777 Canis lupus familiaris
100125883 Bos taurus
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