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KH-Type Splicing Regulatory Protein Proteins (KHSRP)

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]\; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010].. Additionally we are shipping KHSRP Antibodies (61) and KHSRP Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KHSRP 8570 Q92945
KHSRP 16549 Q3U0V1
KHSRP 171137 Q99PF5
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Top KHSRP Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,101.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KHSRP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for KH-Type Splicing Regulatory Protein (KHSRP) Interaction Partners

Human KH-Type Splicing Regulatory Protein (KHSRP) interaction partners

  1. Khsrp as a highly regulated RBP (show RBP4 Proteins) in response to genotoxic stress.

  2. Functional analysis of selected regulated proteins revealed that knockdown of HNRPD (show HNRNPD Proteins), PHB2 (show PHB2 Proteins) and UB2V2 (show UBE2V2 Proteins) can increase HCMV replication, while knockdown of A4 and KSRP resulted in decreased HCMV replication.

  3. The ability of KSRP to integrate different levels of gene expression is required for proper immune response. [Review]

  4. subcellular localization of KSRP is regulated by competing interactions with DDX1 (show DDX1 Proteins) or 14-3-3 (show YWHAQ Proteins)

  5. KSRP induces enhanced processing of pri- and pre-miR (show MLXIP Proteins)-155 in cystic fibrosis (show S100A8 Proteins) lung epithelial cells.

  6. Enterovirus 71 infection cleaved FBP2, which altered its function when its carboxyl terminus was cleaved.

  7. Binding of the human KSRP protein to let-7 miRNA precursors positively regulates their processing to mature let-7, thereby contributing to control of cell proliferation, apoptosis and differentiation

  8. The role of KSRP in mRNA decay and microRNA precursor maturation.

  9. RACK1 (show GNB2L1 Proteins) binds to KH-type splicing regulatory protein (KSRP), a member of the Dicer (show DICER1 Proteins) complex, and is required for the recruitment of mature miRNAs to the RNA-induced silencing complex (RISC).

  10. KHSRP was identified as being involved in the regulation of rpL3 (show RPL3 Proteins) gene expression via alternative pre-mRNA splicing.

Mouse (Murine) KH-Type Splicing Regulatory Protein (KHSRP) interaction partners

  1. KSRP is critical in governing hepatic lipid metabolism through controlling Per2 (show PER2 Proteins) expression

  2. KSRP modulation of GAP-43 (show GAP43 Proteins) mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

  3. This study reveals the in vivo function of KSRP in controlling brown-like transformation of subcutaneous/inguinal white adipose tissue through post-transcriptional regulation of miR (show MLXIP Proteins)-150 expression.

  4. This study reveals a novel in vivo function of KSRP in controlling adipose lipolysis through posttranscriptional regulation of miR (show MLXIP Proteins)-145 expression.

  5. KSRP is required to maintain P19 cells in undifferentiated state and that its inactivation can orient cells towards neural differentiation.

  6. Our results outline a critical role for KSRP in regulating pro-inflammatory mediators and have implications for a wide range of CNS inflammatory and autoimmune diseases.

  7. We have identified a post-transcriptional regulatory network active during mouse pituitary development in which the expression of the hormone alphaGSU (show CGA Proteins) is increased by let7b/c through downregulation of KSRP

  8. data suggest that miR (show MLXIP Proteins)-27b targets KSRP and modulates iNOS (show NOS2 Proteins) mRNA stability following C. parvum infection, a process that may be relevant to the regulation of epithelial anti-microbial defense in general

  9. PI3K/AKT (show AKT1 Proteins) signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis.

  10. function of KSRP in innate immunity by negatively regulating interferon (show IFNA Proteins) production

KHSRP Protein Profile

Protein Summary

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997

Gene names and symbols associated with KHSRP

  • KH-type splicing regulatory protein (KHSRP)
  • KH-type splicing regulatory protein (khsrp)
  • KH-type splicing regulatory protein (LOC100356263)
  • KH-type splicing regulatory protein (Khsrp)
  • 6330409F21Rik protein
  • Fbp2 protein
  • fc94c12 protein
  • Fubp2 protein
  • KHSRP protein
  • Ksrp protein
  • Marta1 protein
  • VgRBP71 protein
  • wu:fb25b12 protein
  • wu:fc10e10 protein
  • wu:fc94c12 protein
  • zgc:163038 protein

Protein level used designations for KHSRP

KH-type splicing regulatory protein , KH-type splicing regulatory protein (FUSE binding protein 2) , FUSE binding protein 2 , far upstream element-binding protein 2 , fc10e10 , FUSE-binding protein 2 , KH type-splicing regulatory protein , p75 , KSRP , MAP2 RNA trans-acting protein 1 , MAP2 RNA trans-acting protein MARTA1 , zipcode-binding protein 2

GENE ID SPECIES
455640 Pan troglodytes
485022 Canis lupus familiaris
702544 Macaca mulatta
100158419 Xenopus laevis
100170586 Xenopus (Silurana) tropicalis
100356263 Oryctolagus cuniculus
573145 Danio rerio
100065608 Equus caballus
8570 Homo sapiens
16549 Mus musculus
171137 Rattus norvegicus
374140 Gallus gallus
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