KH-Type Splicing Regulatory Protein Proteins (KHSRP)

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]\; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010].. Additionally we are shipping KHSRP Antibodies (68) and KHSRP Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KHSRP 8570 Q92945
KHSRP 16549 Q3U0V1
KHSRP 171137 Q99PF5
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Top KHSRP Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,101.17
Details

KHSRP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for KH-Type Splicing Regulatory Protein (KHSRP) Interaction Partners

Human KH-Type Splicing Regulatory Protein (KHSRP) interaction partners

  1. mechanistic evidence that KSRP promotes the down-regulation of Spry4 (show SPRY4 Proteins) by a previously unidentified mechanism, i.e. post-transcriptional mRNA regulation.

  2. The interaction between the KLHL12 (show KLHL12 Proteins) and the C-terminal domain of KHSRP contributed to KHSRP ubiquitination, leading to downregulation of enterovirus internal ribosome entry sites-mediated translation in infected cells.

  3. The miRNA biogenesis factors, DDX17 (show DDX17 Proteins) and KHSRP, regulate the protein level of Ago2 (show EIF2C2 Proteins) in human cells.

  4. Results show that KHSRP protein is highly expressed in osteosarcoma cells and provide evidence for its important roles in regulatory controls of osteosarcoma pathogenesis.

  5. High FBP2 expression is associated with doxorubicin resistance in breast cancer .

  6. Further analyses indicated that KHSRP was involved in miR-26a maturation and inhibited the expression of PTEN in small cell lung cancer cells

  7. The expression of KSRP in liver epithelial cells controlled by mir (show MLXIP Proteins)-27b.

  8. Khsrp as a highly regulated RBP (show RBP4 Proteins) in response to genotoxic stress.

  9. Functional analysis of selected regulated proteins revealed that knockdown of HNRPD (show HNRNPD Proteins), PHB2 (show PHB2 Proteins) and UB2V2 (show UBE2V2 Proteins) can increase HCMV replication, while knockdown of A4 and KSRP resulted in decreased HCMV replication.

  10. The ability of KSRP to integrate different levels of gene expression is required for proper immune response. [Review]

Mouse (Murine) KH-Type Splicing Regulatory Protein (KHSRP) interaction partners

  1. IFN-gamma (show IFNG Proteins) production was increased in spleen cells of KSRP(-/-) mice.

  2. Resveratrol causes a shift from the mesenchymal-specific forms of these factors to the respective epithelial forms and increases the expression of the RNA-binding proteins KHSRP and hnRNPA1 (show HNRNPA1 Proteins).

  3. KSRP is critical in governing hepatic lipid metabolism through controlling Per2 (show PER2 Proteins) expression

  4. KSRP modulation of GAP-43 (show GAP43 Proteins) mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

  5. This study reveals the in vivo function of KSRP in controlling brown-like transformation of subcutaneous/inguinal white adipose tissue through post-transcriptional regulation of miR (show MLXIP Proteins)-150 expression.

  6. This study reveals a novel in vivo function of KSRP in controlling adipose lipolysis through posttranscriptional regulation of miR (show MLXIP Proteins)-145 expression.

  7. KSRP is required to maintain P19 cells in undifferentiated state and that its inactivation can orient cells towards neural differentiation.

  8. Our results outline a critical role for KSRP in regulating pro-inflammatory mediators and have implications for a wide range of CNS inflammatory and autoimmune diseases.

  9. We have identified a post-transcriptional regulatory network active during mouse pituitary development in which the expression of the hormone alphaGSU (show CGA Proteins) is increased by let7b/c through downregulation of KSRP

  10. data suggest that miR (show MLXIP Proteins)-27b targets KSRP and modulates iNOS (show NOS2 Proteins) mRNA stability following C. parvum infection, a process that may be relevant to the regulation of epithelial anti-microbial defense in general

KHSRP Protein Profile

Protein Summary

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997

Gene names and symbols associated with KHSRP

  • KH-type splicing regulatory protein (KHSRP)
  • KH-type splicing regulatory protein (khsrp)
  • KH-type splicing regulatory protein (LOC100356263)
  • KH-type splicing regulatory protein (Khsrp)
  • 6330409F21Rik protein
  • Fbp2 protein
  • fc94c12 protein
  • Fubp2 protein
  • KHSRP protein
  • Ksrp protein
  • Marta1 protein
  • VgRBP71 protein
  • wu:fb25b12 protein
  • wu:fc10e10 protein
  • wu:fc94c12 protein
  • zgc:163038 protein

Protein level used designations for KHSRP

KH-type splicing regulatory protein , KH-type splicing regulatory protein (FUSE binding protein 2) , FUSE binding protein 2 , far upstream element-binding protein 2 , fc10e10 , FUSE-binding protein 2 , KH type-splicing regulatory protein , p75 , KSRP , MAP2 RNA trans-acting protein 1 , MAP2 RNA trans-acting protein MARTA1 , zipcode-binding protein 2

GENE ID SPECIES
455640 Pan troglodytes
485022 Canis lupus familiaris
702544 Macaca mulatta
100158419 Xenopus laevis
100170586 Xenopus (Silurana) tropicalis
100356263 Oryctolagus cuniculus
573145 Danio rerio
100065608 Equus caballus
8570 Homo sapiens
16549 Mus musculus
171137 Rattus norvegicus
374140 Gallus gallus
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