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KIAA0319 encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. Additionally we are shipping KIAA0319 Antibodies (35) and many more products for this protein.
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The KIAA0319 gene is associated with both reading ability and general cognition, but in different ways. The effect on IQ appears to occur earlier in development and is transient, whereas the effect of reading ability occurs later and is moderated by antenatal maternal stress.
Markers in DYX2 genes KIAA0319 and FAM65B (show FAM65B Proteins) were associated with cortical thickness in the left developing orbitofrontal region and global fractional anisotropy, respectively. KIAA0319 and ACOT13 (show ACOT13 Proteins) were suggestively associated with overall fractional anisotropy and left pars (show EPRS Proteins) opercularis cortical thickness, respectively.
These results indicate that KIAA0319L (show KIAA0319L Proteins) is the fourth of four candidate dyslexia susceptibility genes that is involved in neuronal migration, which supports the association of abnormal neuronal migration with developmental dyslexia.
the association of DCDC2 (show DCDC2 Proteins) and KIAA0319 with Developmental dyslexia in Chinese population should be further validated
our findings suggest that KIAA0319 is associated with a reading-related cognitive skill
KIAA0319 and ROBO1 (show ROBO1 Proteins) genes, and developmental dyslexia (DD), related neuropsychological phenotypes and comorbid language and mathematical (dis)abilities in a large cohort of 493 Italian nuclear families ascertained through a proband with a diagnosis of DD.
This study demonstrated the association of developmental dyslexia with rs4504469 of KIAA0319 and not with any single-nucleotide polymorphisms of DCDC2 (show DCDC2 Proteins).
results suggested that the 931C > T variant in KIAA0319, but not the -3G > A in DYX1C1 (show DYX1C1 Proteins), was significantly associated with the risk of dyslexia
The results of this study found that KIAA0319 gene contained polymorphisms that were significantly associated with white matter volume in the left temporo-parietal region and that white matter volume influenced reading ability.
Association study of a functional genetic variant in KIAA0319 in German dyslexics.
This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, dyslexia susceptibility 2
, dyslexia-associated protein KIAA0319
, dyslexia-associated protein KIAA0319 homolog