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Functions in mitochondrial tRNA maturation. Additionally we are shipping KIAA0391 Antibodies (27) and KIAA0391 Proteins (4) and many more products for this protein.
This study presents the crystal structure of human MRPP3, which features a remarkably distorted and hence non-productive active site that authors propose will switch to a fully productive state only upon association with MRPP1 (show RG9MTD1 ELISA Kits), MRPP2 (show HSD17B10 ELISA Kits) and pre-tRNA substrate.
using a genome-wide association study, found that posttranscriptional modification of functionally important sites in mitochondrial transfer RNAs (tRNAs) is under strong genetic control, largely driven by a missense mutation in MRPP3
Inhibition of mitochondrial RNase P by beta-amyloid is an unspecific effect and is not mediated by beta-amyloid interaction with SDR5C1 (show HSD17B10 ELISA Kits).
Haplotypes in KIAA0391 and PSMA6 (show PSMA6 ELISA Kits) genes is a genetic link for myocardial infarction and coronary artery disease.
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends (By similarity).
mitochondrial RNase P protein 3
, mitochondrial RNase P subunit 3
, mitochondrial ribonuclease P protein 3
, proteinaceous RNase P