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CTIF is a component of the CBP80 (NCBP1\\\\; MIM 600469)\\/CBP20 (NCBP2\\\\; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. Additionally we are shipping KIAA0427 Antibodies (14) and KIAA0427 Proteins (3) and many more products for this protein.
association of SNPs in LCP1 (show LCP1 ELISA Kits) and CTIF with hearing
Study reveals that Ago2 (show EIF2C2 ELISA Kits), but not Ago2F2V2, inhibits the binding of CBP80 (show NCBP1 ELISA Kits)/20 to cap structure.
a new MIF4G domain-containing protein (show MIF4GD ELISA Kits), CTIF that interacts directly with CBP80 (show NCBP1 ELISA Kits) and is part of the CBP80 (show NCBP1 ELISA Kits)/20-dependent translation initiation complex [CBP80/20-dependent translation initiation factor, CTIF]
CTIF is a component of the CBP80 (NCBP1\; MIM 600469)/CBP20 (NCBP2\; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009