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Required for association of the cohesin complex with chromatin during interphase. Additionally we are shipping KIAA0892 Proteins (1) and many more products for this protein.
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Human Polyclonal KIAA0892 Primary Antibody for WB - ABIN2786102
Seitan, Banks, Laval, Majid, Dorsett, Rana, Smith, Bateman, Krpic, Hostert, Rollins, Erdjument-Bromage, Tempst, Benard, Hekimi, Newbury, Strachan: Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance. in PLoS biology 2006
Absence of Mau2 in neural crest cells causes a severe disruption of craniofacial development.
In spermatocytes, Nipbl (show NIPBL Antibodies)/Mau2 then relocalises to chromocenters, whereas in oocytes it remains bound to chromosomal axes throughout prophase to dictyate arrest.
specific novel mutations at the N-terminus of the MAU2-interacting domain of NIBPL result in markedly reduced MAU2 binding.
Human MAU-2 family member has weak similarity to yeast Scc4 and is associated with Scc2, bound to chromatin from telophase until prophase, and required for association of cohesin with chromatin during interphase
Required for association of the cohesin complex with chromatin during interphase. Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity).
, Cohesin loading complex subunit SCC4 homolog
, Protein MAU-2
, sister chromatid cohesion protein
, MAU2 chromatid cohesion factor homolog
, Scc4-like protein
, cohesin loading complex subunit SCC4 homolog
, protein MAU-2
, sister chromatid cohesion 4