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Karyopherin alpha 1 (Importin alpha 5) (KPNA1) ELISA Kits

The import of proteins into the nucleus is a process that involves at least 2 steps. Additionally we are shipping Karyopherin alpha 1 (Importin alpha 5) Antibodies (87) and Karyopherin alpha 1 (Importin alpha 5) Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse KPNA1 KPNA1 16646 Q60960
Anti-Rat KPNA1 KPNA1 288064  
Anti-Human KPNA1 KPNA1 3836 P52294
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More ELISA Kits for Karyopherin alpha 1 (Importin alpha 5) Interaction Partners

Mouse (Murine) Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. mTOR (show FRAP1 ELISA Kits) and protein phosphatase 2A catalytically control the constitutive nuclear import of latent STAT1 (show STAT1 ELISA Kits) by KPNA1, which are key modulators of STAT1 (show STAT1 ELISA Kits) expression and apoptosis.

  2. KPNA1 knockdown increased myoblast proliferation.

  3. Importin alpha (show KPNA4 ELISA Kits) binding and the nuclear import of myopodin (show SYNPO2 ELISA Kits) are regulated by the serine/threonine phosphorylation-dependent binding of myopodin (show SYNPO2 ELISA Kits) to 14-3-3 (show YWHAQ ELISA Kits). These results establish a novel paradigm for the promotion of nuclear import by 14-3-3 (show YWHAQ ELISA Kits) binding.

  4. PTH1R (show PTH1R ELISA Kits) forms a complex with the transport regulatory proteins, importin alpha(1) and importin beta (show KPNB1 ELISA Kits), and nuclear PTH1R (show PTH1R ELISA Kits) is associated with the nucleoplasm

  5. Here, we show that the expression of importin-alpha (show KPNA4 ELISA Kits) subtypes is strictly regulated during neural differentiation of mouse embryonic stem (ES) cells, and that the switching of importin-alpha (show KPNA4 ELISA Kits) subtype expression is critical for neural differentiation.

  6. Absence of importin (show KPNA4 ELISA Kits) a5 during mouse development does not significantly interfere with neuronal differentiation and brain development.

Human Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. Data show that cytoskeleton associated protein 5 (chTOG (show CKAP5 ELISA Kits)) only weakly promotes importin (show KPNA4 ELISA Kits)-regulated microtubule nucleation, but acts synergistically with TPX2 (show TPX2 ELISA Kits) protein.

  2. BIG3 (show WDR5 ELISA Kits) may block the KPNAs (KPNA1, KPNA5 (show KPNA5 ELISA Kits), and KPNA6 (show KPNA6 ELISA Kits)) binding region(s) of PHB2 (show PHB2 ELISA Kits).

  3. miR-223 downregulation promotes glomerular endothelial cell activation by upregulating importin alpha4 and alpha5 in IgA nephropathy

  4. Bel1 fragment with residues 215-223, which bears the NLS (show ALDH1A2 ELISA Kits), interacts with KPNA1, KPNA6 (show KPNA6 ELISA Kits), and KPNA7 (show KPNA6 ELISA Kits).

  5. Results indicate CTNNBL1 (show CTNNBL1 ELISA Kits) as a unique selective nuclear localization signals (NLSs)-binding protein with striking differences from karyopherin-alphas.

  6. This supports the notion that de novo mutations KPNA1 in are extremely rare in schizophrenia

  7. LRRC59 facilitates transport of cytosolic FGF1 through nuclear pores by interaction with Kpns and movement of LRRC59 along the ER and NE membranes

  8. mTOR (show FRAP1 ELISA Kits) and protein phosphatase 2A catalytically control the constitutive nuclear import of latent STAT1 (show STAT1 ELISA Kits) by KPNA1, which are key modulators of STAT1 (show STAT1 ELISA Kits) expression and apoptosis.

  9. the requirement for and the regulation of CAS (show CSE1L ELISA Kits) in the functioning of the Vpr-Impalpha complex

  10. Nucleoporin Nup50 (show NUP50 ELISA Kits) stabilizes closed conformation of armadillo (show PKP1 ELISA Kits) repeat 10 in importin (show KPNA4 ELISA Kits) alpha5.

Pig (Porcine) Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. Nsp1beta inhibits interferon-activated STAT1 (show STAT1 ELISA Kits)/STAT2 (show STAT2 ELISA Kits) signal transduction by inducing karyopherin-alpha1 degradation.

Cow (Bovine) Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. Bovine ephemeral fever rhabdovirus alpha1 protein binds bovin importin (show KPNA4 ELISA Kits) beta1 and importin 7 (show IPO7 ELISA Kits).

Xenopus laevis Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. Data show that either an excess or a lack of importin alpha (show KPNA4 ELISA Kits) blocks nuclear envelope (NE) assembly in vitro, and that it also functions in NE assembly in conjunction with nuclear localization signal-containing partner proteins.

Karyopherin alpha 1 (Importin alpha 5) (KPNA1) Antigen Profile

Antigen Summary

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with KPNA1

  • importin alpha-1 subunit (EHI_124900) antibody
  • karyopherin alpha 1 (importin alpha 5) (KPNA1) antibody
  • karyopherin (importin) alpha 1 (Kpna1) antibody
  • karyopherin alpha 1 (Kpna1) antibody
  • karyopherin alpha 1 (importin alpha 5) (kpna1) antibody
  • karyopherin alpha 7 (importin alpha 8) (kpna7) antibody
  • AW494490 antibody
  • IPOA5 antibody
  • kpna1 antibody
  • mSRP1 antibody
  • NPI-1 antibody
  • NPI1 antibody
  • RCH2 antibody
  • si:ch211-161h7.7 antibody
  • SRP1 antibody

Protein level used designations for KPNA1

importin alpha-1 subunit , Importin subunit alpha-1 , importin subunit alpha-5 , karyopherin subunit alpha-1 , NPI-1 , RAG cohort protein 2 , SRP1-beta , importin alpha-S1 , importin subunit alpha-1 , m-importin-alpha-S1 , nucleoprotein interactor 1 , importin alpha 5 , importin alpha-5 , karyopherin (importin) alpha 1 , karyopherin/importin alpha-1 , importin-alpha-S1 , recombination activating gene cohort 2 , importin alpha 1a

GENE ID SPECIES
6220066 Entamoeba histolytica HM-1:IMSS
100172964 Pongo abelii
16646 Mus musculus
288064 Rattus norvegicus
3836 Homo sapiens
478585 Canis lupus familiaris
397235 Sus scrofa
539679 Bos taurus
572542 Danio rerio
418271 Gallus gallus
398026 Xenopus laevis
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