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anti-Karyopherin alpha 4 (Importin alpha 3) (KPNA4) Antibodies

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Additionally we are shipping KPNA4 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KPNA4 16649 O35343
KPNA4 3840 O00629
KPNA4 361959  
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Top anti-KPNA4 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-KPNA4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Hela cell lysate WB Suggested Anti-KPNA4  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Hela cell lysate  KPNA4 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB The anti-Importin alpha-4 Pab (ABIN388688) is used in Western blot to detect Importin alpha-4 in Hela (left), mouse brain (middle), and HepG2 (right)cell line/tissue lysates. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185160 staining (0.5µg/ml) of Human Testis lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Figure 1: ABIN185160 (3µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. Figure 2: see Application Notes. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KPNA1 in Hela cell lysate with KPNA1 antibody at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Mouse Rat Un-conjugated ELISA, WB 200 μg Log in to see 7 to 8 Days
$434.50
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image KPNA4 antibody [C3], C-term detects KPNA4 protein by Western blot analysis. A. 30 µg Rat2 whole cell lysate/extract 7.5 % SDS-PAGE KPNA4 antibody [C3], C-term , dilution: 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using QIP1 , antibody at 1:200 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details

KPNA4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-KPNA4 Antibodies

  1. Mouse (Murine) Monoclonal KPNA4 Primary Antibody for ELISA, WB - ABIN2452037 : Yasuhara, Shibazaki, Tanaka, Nagai, Kamikawa, Oe, Asally, Kamachi, Kondoh, Yoneda: Triggering neural differentiation of ES cells by subtype switching of importin-alpha. in Nature cell biology 2007 (PubMed)
    Show all 4 references for ABIN2452037

  2. Human Polyclonal KPNA4 Primary Antibody for EIA, WB - ABIN357323 : Dvorin, Bell, Maul, Yamashita, Emerman, Malim: Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import. in Journal of virology 2002 (PubMed)
    Show all 3 references for ABIN357323

  3. Human Polyclonal KPNA4 Primary Antibody for IHC, ELISA - ABIN185160 : Seki, Tada, Katada, Enomoto: Cloning of a cDNA encoding a novel importin-alpha homologue, Qip1: discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQL. in Biochemical and biophysical research communications 1997 (PubMed)
    Show all 2 references for ABIN185160

  4. Human Polyclonal KPNA4 Primary Antibody for WB - ABIN388688 : Zhang, Dong, Zhang, He, Chen, Cao, Li, Xiao, Lu, Pan: Identification of a novel nuclear localization signal of baculovirus late expression factor 11. in Virus research 2014 (PubMed)

  5. Human Polyclonal KPNA4 Primary Antibody for EIA, WB - ABIN783731 : Moroianu: Molecular mechanisms of nuclear protein transport. in Critical reviews in eukaryotic gene expression 1997 (PubMed)

  6. Cow (Bovine) Polyclonal KPNA4 Primary Antibody for EIA, IHC (p) - ABIN374394 : Huenniger, Krämer, Soom, Chang, Köhler, Depping, Kehlenbach, Kaether: Notch1 signaling is mediated by importins alpha 3, 4, and 7. in Cellular and molecular life sciences : CMLS 2010 (PubMed)

  7. Chicken Polyclonal KPNA4 Primary Antibody for WB - ABIN2774081 : Yeung, Chen, Tsai, Zhang, Chen: Daxx contains two nuclear localization signals and interacts with importin alpha3. in Journal of cellular biochemistry 2008 (PubMed)

More Antibodies against KPNA4 Interaction Partners

Fruit Fly (Drosophila melanogaster) Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. Expression of DnaJ-1 (show DNAJB1 Antibodies) potently suppresses alpha1ACT-dependent degeneration , concomitant with decreased aggregation of the pathogenic protein. Mutating the nuclear importer karyopherin a3 also leads to reduced toxicity from pathogenic CACNA1A (show CACNA1A Antibodies)

  2. These results reveal that the nuclear transport of Notch (show NOTCH1 Antibodies) intracellular domain (Notch (show NOTCH1 Antibodies)-ICD)is mediated by the canonical Importin-alpha3/Importin-beta (show KPNB1 Antibodies) transport pathway.

  3. each Imp (show BRAP Antibodies)-alpha protein carries during Drosophila spermatogenesis distinct, albeit overlapping, functions that may involve nuclear import of proteins, microtubule organisation, and other yet unknown processes

  4. Data show that Drosophila Naked cuticle (Nkd (show NKD1 Antibodies)) engages the nuclear import adaptor Importin-alpha3 to antagonize Wnt (show WNT4 Antibodies)/beta-catenin signaling.

Arabidopsis thaliana Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. MOS6, identified by positional cloning, encodes importin alpha3, one of eight alpha importins in Arabidopsis [MOS6]

Mouse (Murine) Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. Our results showed that miR (show MLXIP Antibodies)-181 family expression was closely correlated with TCGA subtypes and patients' overall survival, indicating that miR (show MLXIP Antibodies)-181b.

  2. Loss of importin alpha 4 is associated with oxidative stress.

  3. IMPalpha4 overexpression induced a significant decrease in Oct3/4 (show POU5F1 Antibodies) protein levels compared to control transfections. IMPalpha4 protein showed a unique and striking shift in subcellular localization from the nucleus to the cytoplasm during differentiation.

  4. Expression of importin alpha3, a protein involved in p50 (show LSP1 Antibodies)/p65 (show NFkBP65 Antibodies) nuclear import, was decreased in colonic mucosa cells of (show PHB Antibodies)transgenic mice overexpressing human prohibitin.

  5. In postnatal testes, importin alpha3 and alpha4 in spermatocytes, spermatids, and Sertoli cells display cytoplasmic and nuclear localization, respectively.

Cow (Bovine) Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. These results suggest that the bovine adenovirus-3 52K protein contains a bipartite nuclear localization signal, which preferentially utilize an importin alpha3 nuclear import receptor-mediated pathway to transport the 52K protein to the nucleus.

Human Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. Our results showed that miR (show MLXIP Antibodies)-181 family expression was closely correlated with TCGA subtypes and patients' overall survival, indicating that miR (show MLXIP Antibodies)-181b.

  2. Karyopherin alpha 3 (show KPNA3 Antibodies) and karyopherin alpha 4 proteins mediate the nuclear import of methyl-CpG binding protein 2 (show MBD2 Antibodies).

  3. miR-223 downregulation promotes glomerular endothelial cell activation by upregulating importin alpha4 and alpha5 in IgA nephropathy

  4. upon DNA damage transport adaptor importin-alpha4 imports XPA into the nucleus in an ATR-dependent manner.

  5. Importin alpha3/Qip1 is involved in multiplication of mutant influenza virus with alanine mutation at amino acid 9 independently of nuclear transport function.

  6. Impalpha3 is an HIV integrase-interacting cofactor and is required for efficient HIV-1 nuclear import and replication.

  7. stress-induced accumulation of non-ubiquitinated p53 (show TP53 Antibodies) in the cytoplasm promotes interaction with importin-alpha3 and rapid import

  8. Expression of importin alpha3, a protein involved in p50 (show CD40 Antibodies)/p65 (show GORASP1 Antibodies) nuclear import, was decreased in cells overexpressing PHB (show PHB Antibodies).

  9. Our results indicate that the nuclear import of RHA is mediated by the importin-alpha3/importin-beta (show KPNB1 Antibodies)-dependent pathway and suggest that the specificity for importin may regulate the functions of cargo proteins.

  10. Daxx (show DAXX Antibodies) interacts selectively with importin alpha3 through its NLS1 and NLS2 sequences. Conversely, importin alpha3 utilizes two NLS (show ALDH1A2 Antibodies)-binding sites for Daxx (show DAXX Antibodies) interaction, suggesting that it mediates nuclear import of Daxx (show DAXX Antibodies).

KPNA4 Antigen Profile

Protein Summary

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Gene names and symbols associated with KPNA4

  • karyopherin alpha3 (Kap-alpha3) antibody
  • Importin alpha 3 (MOS6) antibody
  • importin alpha 3 (LOC100533341) antibody
  • karyopherin alpha 4 (importin alpha 3) (LOC100224013) antibody
  • karyopherin (importin) alpha 4 (Kpna4) antibody
  • karyopherin alpha 4 (importin alpha 3) (KPNA4) antibody
  • karyopherin alpha 4 (importin alpha 3) (Kpna4) antibody
  • karyopherin alpha 4 (importin alpha 3) (kpna4) antibody
  • 6 antibody
  • 0335/13 antibody
  • 1110058D08Rik antibody
  • alphaKap3 antibody
  • ATIMPALPHA3 antibody
  • CG9423 antibody
  • Dalpha3 antibody
  • dimpalpha3 antibody
  • dKap-alpha3 antibody
  • Dmel\\CG9423 antibody
  • imp-a3 antibody
  • imp-alpha3 antibody
  • IMPA-3 antibody
  • Imp alpha-3 antibody
  • impalpha3 antibody
  • imp alpha3 antibody
  • importin antibody
  • IMPORTIN ALPHA 3 antibody
  • IMPORTIN ALPHA ISOFORM 3 antibody
  • ipoa3 antibody
  • Kap-?3 antibody
  • KAP-ALPHA3 antibody
  • Kapalpha3 antibody
  • Kap alpha3 antibody
  • Kpna3 antibody
  • l(3)S033513 antibody
  • LOC100224013 antibody
  • MODIFIER OF SNC1 antibody
  • qip1 antibody
  • srp3 antibody
  • T10M13.16 antibody
  • T10M13_16 antibody

Protein level used designations for KPNA4

CG9423-PA , CG9423-PB , CG9423-PC , CG9423-PD , Importin-alpha3 , Kap-alpha3-PA , Kap-alpha3-PB , Kap-alpha3-PC , Kap-alpha3-PD , dImportin-alpha3 , importin a3 , importin alpha , importin alpha-3 , importin alpha3 , karyopherin a3 , karyopherin alpha4 , karyopherin-alpha3 , karyopherin-alpha4 , importin alpha 3 , karyopherin alpha 4 (importin alpha 3) , importin alpha Q1 , importin subunit alpha-3 , importin subunit alpha-4 , karyopherin subunit alpha-4 , qip1 , karyopherin (importin) alpha 4 , predicted role in nuclear import

GENE ID SPECIES
41158 Drosophila melanogaster
827472 Arabidopsis thaliana
100533341 Aplysia californica
100224013 Taeniopygia guttata
16649 Mus musculus
535090 Bos taurus
3840 Homo sapiens
478680 Canis lupus familiaris
361959 Rattus norvegicus
432010 Xenopus laevis
425012 Gallus gallus
Selected quality suppliers for anti-KPNA4 (KPNA4) Antibodies
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